Exam 6 Part 2 – Flashcards
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It occurs when an individual is exposed to an allergen for the first time
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All of the following are true of hypersensitivity EXCEPT...
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Found in basophils and mast cells
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The chemical mediators of anaphylaxis are...
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Bone Marrow Transplant
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Graft-versus-host disease will most likely be a complication of a(n)
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CTLs and activated macrophages
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A healthy immune system destroys cancer cells with...
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Complement fixation
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The symptoms of an immune complex reaction are due to...
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Complexes of IgM and IgG and also complement in joints
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Rheumatoid arthritis is due to deposition of...
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Sensitized T cells
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Allergic contact dermatitis is due to...
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gp120 combining with the CD4+ receptor
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Attachment of HIV to the target cell depends on...
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They can detect antibodies but not antigens
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All of the following pertain to serological tests EXCEPT...
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Antigen
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The process of desensitization to prevent allergies involves the injection of increasing amounts of...
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They involve helper T cells
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Which of the following statements about type I reactions is FALSE?
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Hemolytic disease of the newborn is an example
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Which of the following statements about type IV reactions is FALSE?
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It is used to treat some breast cancer patients
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All of the following are false regarding Herceptin EXCEPT...
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Immunotherapy
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Which of the following utilizes a combination of monoclonal antitumor antibody and immunotoxin?
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Vaccines are not effective against viral infections
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All of the following are reasons why an HIV vaccination has not been developed EXCEPT
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They express MHC II antigens
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Which of the following statements about human embryonic stem cells is FALSE?
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Endothelial cells are damaged
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In immune complex reaction shown in the figure, what is the end result of the reaction?
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T helper cells, macrophages, and dendritic cells
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HIV spikes attach to CD4+ receptors found on
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Attenuated vaccine
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Which of the following is the least likely vaccine against HIV?
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Destruction of viral ribosomes
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Chemotherapy to inhibit the progression of HIV infection utilizes all of the following mechanisms EXCEPT
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Measuring viral RNA
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During asymptomatic phase I of HIV disease, HIV infection is diagnosed by...
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IgE antibodies
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Anaphylaxis is the term for reactions caused when certain antigens combine with...
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They include any tissue transplanted from a pig
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All of the following regarding "privileged sites" are true EXCEPT
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Transplant rejections
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All of the following are considered examples of type I hypersensitivity EXCEPT
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Drug binds to platelets
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All of the following lead to drug-induced thrombocytopenic purpura. Which occurs first?
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Autoimmune diseases
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Immunodeficiencies are a result of all of the following EXCEPT
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Antibodies react to cell-surface antigens
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Which of the following describes a cytotoxic autoimmune reaction?
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Cytokines
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Symptoms of delayed cell-mediated reactions are due to...
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IgG
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Which type of response does the process of desensitization produce?
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Trypan blue enters the cells
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The following events occur if human cells expressing HLA-I are mixed with anti-HLA-I, complement, and trypan blue. What step indicates the cells are HLA-I?
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Immune complex autoimmunity
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In rheumatoid arthritis, IgM, IgG, and complement deposit in joints. This is an example of...
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Phase 3
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The number of T cells drops to below 200 cells/microliter in which phase of HIV infection?
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Lymphadenopathy
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The initial symptom of HIV infection is
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True
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True or False: Individuals who do not express CCR5 are highly resistant to infection by HIV.
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False
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True or False: Vaccines against HIV have proven to be very effective in halting the spread of disease.
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False
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True or False: All hypersensitivities involve antibody-antigen reactions.
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True
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True or False: HIV is a retrovirus with single-stranded RNA.
