USMLE Tumor Markers – Flashcards
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CEA
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1. Colorectal 2. Pancreatic Cancers 3. Gastric 4.Breast 5. Medullary thyroid ca. (visceral association + breast/thyroid)
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alpha-fetoprotein
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1. Hepatocellular 2. Nonseminomatous germ cell tumors
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beta-HCG
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1. Choriocarcinoma 2. Hyatidiform moles
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CA-125
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Ovarian cancer
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S-100
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1. Melanoma 2. Neural tumors 3. Schwannoma
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Alkaline phosphatase
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1. Bone/liver mets. 2. Paget's disease
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Bombesin
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1. Neuroblastoma 2. Lung 3. Gastric
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TRAP
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Hairy cell leukemia (B cell neoplasm)
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CA-19-9
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Pancreatic adenocarcinoma
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Calcitonin
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Medullary thyroid carcinoma
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2 tumor markers associated with pancreatic cancer?
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CA-19-9 and CEA
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2 tumor markers associated with gastric cancer?
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CEA and Bombesin
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2 tumor markers associated with medullary thyroid carcinoma?
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Calcitonin, CEA
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A neuroblastoma tumor marker?
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Bombesin
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A melanoma tumor marker?
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S-100
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2 ovarian cancer tumor markers?
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CA-125; alpha-fetoprotein for nonseminomatous germ cell tumors
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A schwannoma tumor marker?
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S-100
