Science of Diet and Nutrition – Flashcards

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What is the Zone diet?
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Balanced ratio at each meal - 30% protein - 30% fats - 40% carbs Small, frequent meals - <500 calories meal - <100 calories snack
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What is the Weight Watchers diet?
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- Portion and calorie-controlled pre-packaged meals - Heat and eat - Low in saturated, trans fats and sodium - Variety in plans: low glycemic, male or female, seniors, diabetics, etc - Access to other weight control tools such as on-line or in-person support
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What is the Ornish diet?
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- Vegetarian - 70% carbs: Complex & high fiber - 10% fats: Low saturated fats and cholesterol - 20% protein
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What is the Atkins diet?
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- High protein, Moderate fat, Low carb- => 4 phases: - Induction: 2 weeks, <20 g carbs - Ongoing weight Loss: Slow increase in carbs, up to 60 g a day until weight loss stops - Pre-maintenance: 2-3 months, Increase by 10 g carbs a week, Slower weight loss <1 # QW - Maintenance: Up to 90 g carbs, Goal weight achieved
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Describe specific diet changes (diets with modifications, foods to avoid, food to add) for prevention of cardiovascular disease and basic dosages (per day or week).
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- Avoid oxidizing factors and trans-fats - Antioxidant-rich diet - Fiber-rich diet - Low-moderate alcohol intake - Low-moderate caffeine intake - Low intake of regular soda and juices - Switch to beneficial fats
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What is the DASH diet?
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- Low sodium intake - Carbs: 55-60% - Protein: 15-20% - Fat: 25-30%
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What is the Mediterranean diet?
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- High intake of fruits, vegetables, whole grains, legumes, potatoes, nuts, seeds, some dairy (yogurt) - Moderate intake of olive oil (primary monounsaturated oil) - Low-moderate intake of high fat dairy, fish, and poultry - Little or no red meat - Eggs up to 4 times weekly - Low-moderate alcohol intake (red wine) - Seasonal and fresh foods - Daily exercise
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What is the Paleo diet?
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- Hunter-gather or stone age diet - Seasonal, fresh foods - Intake of meat, eggs, fish, vegetables, root vegetables, fruits, nuts - No grains, beans, potatoes, sugar, or dairy—some variety in suggestions
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Name supplements or functional foods that are useful for prevention of cardiovascular disease and why. Be as specific in mechanism as possible.
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- Phytosterols: lowers cholesterol and LDLs by displacing from micelles - Omega-3s/Fish oil: lowers TAGs, increases HDLs - Magnesium: regulates calcium absorption and contractility, relaxes smooth muscle, increases HDLs - Calcium: regulates smooth muscle contraction
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Name a cardio-protective spice or herb.
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- Allium family (garlic, onions) - Hot peppers - Black pepper - Tumeric - Cinnamon - Ginger - Cocoa
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Name several pairs of nutrients that need to be evaluated together when supplementing in diet.
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- calcium and magnesium - sodium and potassium
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Recognize the major therapeutic indications, toxicity and deficiency states of the following nutrients: Calcium, Sodium, Potassium, Vit. E, Vit. K, Niacin.
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- Sodium deficiency: cramping, fatigue, nausea - Sodium toxicity: hypertension, anorexia, vomiting - Potassium deficiency: cardiorespiratory difficulties, psychosis, constipation - Potassium toxicity: diarrhea, arrhythmia, paralysis, hypotension - Vit. E deficiency: rare, hemolytic anemia in infants, disruption of myelin in adults, lipid malabsorption - Vit. E toxicity: 1800 IU a day has shown prolonged blood clotting time, may interfere with Vit. K. - Vit. K deficiency: rare, hemorrhagic disease in newborn, increased bleeding, osteoporosis - Vit. K toxicity: very rare - Niacin deficiency: pellagra (dermatitis, diarrhea, dementia) - Niacin toxicity: vasodilation, nausea, liver problems
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Recognize the major therapeutic indications, toxicity and deficiency states of zinc.
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- Functions: cell growth and replication (epithelium), sexual maturation and reproduction, night vision, immune defenses, taste and appetite, cofactor for enzymes and insulin, prostate cancer prevention - Toxicity: nausea, decreased immune function, increased cholesterol (due to copper deficiency) - Deficiency: growth retardation, skin lesions, impaired wound healing, immune deficiencies, delayed sexual maturation or fertility, behavioral disturbances, decreased or lost sense of smell and taste
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Recognize the major therapeutic indications, toxicity and deficiency states of phosphorus.
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- Function: teeth, bones, nucleic acids, ATP, conjugated proteins, and buffering - Deficiency: due to starvation or large intake of antacids - Toxicity: common in carbonated beverages
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Recognize the major therapeutic indications, toxicity and deficiency states of iodine.
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- Function: thyroid hormone synthesis, BMR regulation - Deficiency: goiter, cretinism - Toxicity: Graves disease, Hashimoto's thyroiditis
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Recognize the major therapeutic indications, toxicity and deficiency states of selenium.
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- Function: glutathione peroxidase, vitamin E sparing, cancer inhibition, conversion of T4 to T3 - Deficiency: weakeness, depigmentation, muscular dystrophy, Keshan disease - Toxicity: loss of hair, nails, teeth
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Recognize the major therapeutic indications, toxicity and deficiency states of chromium.
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- Function: insulin binding, glucose stability, fat and cholesterol metabolism - Deficiency: hyperglycemia, increased TAGs
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Recognize the major therapeutic indications, toxicity and deficiency states of iron.
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- Function: hemoglobin, myoglobin, tyrosine pathway cofactor - Deficiency: anemia, pallor, glossitis, spoon nails, decreased cognition - Toxicity: hemochromatosis, CV disease
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Recognize the major therapeutic indications, toxicity and deficiency states of copper.
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- Functions: cofactor for enzymes, collagen repair, hemoglobin synthesis, anti-inflammatory, myelin synthesis, cancer prevention, cholesterol lowering, skin cancers, prevention of CVD, prevention of stomach cancer - Toxicity: excess levels can be consumed from water, pans and pipes, poor memory, depression, insomnia, joint pain, migraines, Wilson's Disease - Deficiency: liver and brain damage, anemia, neutropenia, vascular degeneration, depigmentation, hypothermia, hypotonia, inborn errors (Menkes Disease)
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Recognize the major therapeutic indications, toxicity and deficiency states of vitamin C.
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- Functions: build and maintain connective tissue, synthesizes collagen, very high concentrations in the adrenals, anti-oxidant, co-factor in tyrosine pathway, increases macrophage activity, anti-histamine effect, glucose transporter for cellular uptake, wound healing, anti-inflammatory - Toxicity: unlikely (excess excreted in urine), oral dosage over 6 g can produce diarrhea or loose stools, oxidation at high levels (prevented by taking buffered vitamin C), oxalate formation leads to kidney stones if already prone to oxalate kidney stones - Deficiency: extreme cases lead to scurvy and can be prevented with 5 mg/day (fatigue, weakness, muscle cramps, aching joints), decreased immune function, decreased glucose tolerance, adrenal fatigue
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Recognize the major therapeutic indications, toxicity and deficiency states of vitamin D.
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- Function: increased calcium absorption and resorption, increased serum calcium, cancer prevention - Toxicity: weakness, vomiting, constipation, calcification of soft tissues, kidneys, lungs and ears, 25000-60000 IU/day for 1-4 months for adults is toxic, 2000-3000 IU/day for children is toxic - Deficiency: rickets, osteomalacia, osteoporosis, psoriasis, cardiovascular disease, seasonal affective disorder, deficiency can be caused by latitude and season, aging, skin pigmentation, clothing, and sunscreen use
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Recognize the major therapeutic indications, toxicity and deficiency states of vitamin A.
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- Function: vision, anti-oxidant, immunity, development - Deficiency: blindness, hyperkeratosis, reduced immunity, diarrhea, loss of tooth enamel and bone mass - Toxicity: fatigue, vomiting, bone pain, dry hair/skin/nails, hepatosplenomegaly
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Recognize the major therapeutic indications, toxicity and deficiency states of folic acid.
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- Function: purine synthesis, RBC/WBC formation, neural tube closure - Deficiency: hypersegmented neutrophils, macrocytic RBC, poor development, glossitis - Toxicity: interference with seizure medications and chemo
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Recognize the major therapeutic indications, toxicity and deficiency states of vitamin B12.
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- Function: methylation, DNA production, cab metabolism, nervous system functioning - Deficiency: pernicious anemia - Toxicity: not likely
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Recognize the major therapeutic indications, toxicity and deficiency states of pantothenic acid.
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- Function: produce ATP in Krebs cycle, transmit nerve impulses, protein metabolism - Deficiency: uncommon - Toxicity: unlikely
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Recognize the major therapeutic indications, toxicity and deficiency states of thiamine.
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- Function: sodium transport, carb metabolism in the brain, Krebs cycle cofactor - Deficiency: mental confusion, muscle weakness, palpitations, Wet beriberi (edema), Dry berberi (muscle wasting), Wernike-Korsakoff (encephalopathy and psychosis) - Toxicity: VERY unlikely
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Recognize the major therapeutic indications, toxicity and deficiency states of biotin.
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- Function: synthesis of amino acids and fatty acids, cofactor for prebiotic bacteria, insulin synthesis and release - Deficiency: elevated glucose and cholesterol, scaling dermatitis, alopecia - Toxicity: unknown
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Describe guidelines for dupuration diet and water-only fasting.
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- Dupuration: hypoallergenic diet and supplements emphasizing liver/gallbladder health and fiber; emphasize vegetables, fruits, protein, nuts/seeds, water; eliminate caffeine, sugar, refined grains, dairy, processed protein - Water-only fasting: prepare by simplifying diet to protein, fruit, veg, whole grain, day before eat only fruit and veg, water-only during fast, end by introducing fresh fruit , then nonstarchy veg, then grains, veg, and proteins
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Name the 5 major routes of elimination in the body.
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- GI tract/ liver/ gall bladder - Kidney/ bladder - Lungs/ respiratory - Skin and lymph - Mental and emotional
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Besides diet changes in the dupuration protocol, name several other supplements, herbs, or treatments can be used to facilitate detoxification, and how they work.
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- fiber: psyllium binds endotoxins - multivitamin: supplies cofactors and antioxidants - lipotrophic: stimulates liver and gall bladder release
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Name steps to safely prepare for and cease a cleansing protocol.
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AND PIE - Abstain from GI destroying foods, drugs, alcohol - Nourish with medical foods for GI healing - Detoxification - Probiotics - Identify food sensitivities, intolerances, dysbiosis - Eliminate food sensitivities, intolerances, dysbiosis
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Name foods high in Beta-Carotene.
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ORANGE: carrots, yams, pumpkin, cantaloupe, apricots, citrus
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Name foods high in Lutein.
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GREEN: peppers, spinach, kale, lettuce, peas, egg yolk
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Name foods high in Lycopene.
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PINK: tomatoes, watermelon, grapefruit, papaya
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Name foods high in Anthocyanidins.
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PURPLE: grapes, berries, cherries, plums
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Name foods high in Isothiocyanates.
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CRUCIFEROUS: broccoli, cabbage, collards, chard, cauliflower, turnip greens
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Name foods high in Isoflavonoids.
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soy and legumes
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Name foods high in Lignans.
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whole grains, nuts, and seeds
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Name specific diet changes to decrease general cancer risk (diets with modifications, foods to avoid, food to add) and basic dosages (per day or week).
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- Garlic: stimulate WBCs - Ginger: stimulate WBCs - Cinnamon: circulatory stimulant, antioxidant - Cayenne: circulatory stimulate, antioxidant - Fermented food + probiotics: stimulate immune response by promoting GI flora balance
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Name supplements that can be used for acute immune support and why.
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- Vitamin A: increase antibodies (10,000 IU) - Vitamin C: increase WBCs (1000 mg) - Zinc: increase NK cells (15-60 mg)
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Name supplements that can be used for chronic immune support and why.
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- Vitamin D: increase WBCs (2000 IU) - Vitamin E: increase NK cells (800 IU) - Selenium: increase NK cells - Carotenoids: increase WBCs, NK cells, T-helper cells
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Name specific diet changes to manage autoimmune disorders (diets with modifications, foods to avoid, food to add) and basic dosages (per day or week).
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- Avoid allergenic foods (gluten, dairy, animal products) - Treat dysbiosis - Treat heavy metal toxicity - Anti-inflammatory diet: eliminate saturated fat; limit grains, dairy, processed meats, refined carbs, sugar, alcohol; increase fruit, veg, legumes, fish
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Identify lifestyle & health factors that increase cancer risk.
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- age, race, genes - family and medical history - environmental toxins - hormone replacement - smoking - obesity - depression - diet and alcohol
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Name supplements used for general cancer prevention and why, and give example of each category.
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- Vitamin C: antioxidant, increase immune function - Vitamin E: increase immune function - Selenium: prevents free radical damage
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Name food categories, diets, or supplements to decrease breast, lung, colon , and prostate cancer risks.
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- Prostate cancer: zinc, vitamin D, selenium, lycopene, fish oil, soy - Breast cancer: vitamin D, soy, lignans, cruciferous veg, indole-3-carbanol, calcium-d-glucarate - Lung: beta-carotene, tumeric, green tea, quercetin, fish oil - Colon: fiber, calcium, beta-carotene, vitamin D
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Identify common elements in cancer treatment approaches using diet as a main therapy.
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- remove broiled/grilled meat - lower intake of animal fat - add legumes (soy) and lycopene
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Name foods or food categories emphasized on the Gerson, macrobiotic, and acid/alkaline diets.
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- Gerson: fresh produce and juice, some grains, no meat, enemas - Macrobiotic: alkaline, whole grains, plant-based proteins, fruit and veg, occasionally fish - Acidic foods: meat, dairy, starch, nuts/seeds, sweets, caffeinated drinks - Alkaline foods: fruits, vegetables, molasses/honey, beans/legumes, spices/herbs
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Name nutrients that are infants need that are not provided in sufficient amounts in breast milk.
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- vitamin D - iron - potassium - carbohydrates
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Name the recommendation for length of breast feeding according to the WHO.
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- exclusive for 6 months - partial until 2 years
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Name when foods introduction should occur, order of food introducion, and any guidelines for proper food introduction.
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- 4-6 months: strained cereal, apples, banana, pear, avocado, sweet potato, squash, green beans - 6-8 months: apricots, peaches, plums, prunes, pumpkin, mango, carrot, peas, zucchini, parsnips, chicken, turkey, yogurt *Only introduce one new food at a time.
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Name common nutrient deficiencies in children.
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- vitamin D - iron - zinc - vitamin C
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Name caloric needs in 1st trimester PG, 2nd trimester, 3rd trimester, and lactation.
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- 1st tri PG: +0 - 2nd tri PG: +340 - 3rd tri PG: + 450 - 0-6 mths lact: + 330 - 6-12 mths lact: + 400
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Name macronutrients that are needed in higher amounts during PG.
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- protein: increase from 50 g to 75 g - fats: increase from 80 g to 90 g - carbs: increase from 160 g to 185 g
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Name micronutrients that are needed in higher amounts during PG and why.
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- vitamin B6: amino acid synthesis - iron: RBC dvlpmt - sodium: prevent water intoxication - calcium: dvlpmt - iodine: prevents cretinism - vitamin C and magnesium: prevent preeclampsia
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Name foods or nutrients to avoid or reduce in PG and lactation and why.
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- vitamin A: can be toxic - alcohol: FAS - caffeine: risk of spontaneous abortion
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Name diet changes or nutrients that are needed during lactation and why.
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- extra 500 calories - increase fluids - smaller, more frequent meals - eliminate food sensitivities - avoid alcohol and caffeine
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Recognize basic guidelines for senior nutrition.
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- males caloric intake: 2000-2800 - female caloric intake: 1600-2200 - adequate fiber and fluid intake - physical activity like walking and resistance training - half the plate veg, quarter of the plate whole grains, quarter of the plate protein
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Name common nutrient concerns in elderly adults and why.
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- vitamins B6, B12, and folic acid - vitamin D: decline in skin concentration and renal conversion, low intake - protein: increase to maintain lean body mass - calcium: low intake
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Name specific nutrients besides calcium that are involved in bone health (excess or deficiency).
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- vitamin D - phosphorus - boron - manganese
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Name a food or food category beneficial for bone health.
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- soy foods - calcium-rich foods
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Name foods, dietary patterns, or food categories detrimental to bone health.
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Decreased activity increases risk of fall and injury. Elimination of heavy metal toxicities helps preserve bone density.
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Name a change to help preserve lean muscle mass in elderly adults.
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Exercise helps reverse the trend of age-related sarcopenia, along with adequate protein intake.
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Name specific diet guidelines with the calorie-restriction diet.
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- decrease calories by 25-30% - avoid simple sugars, flour, and saturated fats - increase vegetable intake, monounsaturated fats, and omega-3-FAs - proteins should be complete and balanced, but not overly abundant
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Name nutrients or foods that may promote longevity and why.
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- CoQ10: protects mitochondria - Antioxidants: protect against atherosclerosis, diabetes, Alzheimer's - Superfoods: acai, allium, barley, buckwheat, beans/lentils, green foods, hot peppers, nuts/seeds, sprouts, yogurt/kefir
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Name nutrients or foods that may prevent dementia and why.
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- fruits, vegetables, fish - high antioxidant beverages: tea and coffee - poly- and mono-unsaturated fatty acids - Mediterranean diet - antioxidants - vitamins B6, B12, and folic acid
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Name avoidances on a vegan diet.
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Avoid meat, seafood, dairy, and any other animal products (honey, leather, etc.)
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Name possible benefits of a vegan diet.
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- lower death rates from CV disease - lower body mass index - lower LDL cholesterol - lower blood pressure - lower rates of type 2 diabetes
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Name common nutrient concerns on a vegan diet and why.
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- protein - calcium - iron - zinc - omega-3-FAs - vitamins B12 and D
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Name common nutrient concerns on a raw food diet and why.
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- protein - calcium - iron
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Name a benefit of a blood type diet.
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- weight loss - GI improvement - increased energy
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Name the general categories of the blood type diet.
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- Type O: high protein - Type A: vegetarian - Type B: balanced omnivore - Type AB: mixed diet in moderation
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Name foods or food categories emphasized on the Weston Price Diet.
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- fish and cod oil - organ and game meats - eggs - raw milk - lacto-fermented food and drink
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Name grains to avoid on a gluten-free diet.
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- wheat (durum, semolina) - barley - rye - triticale - oats
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Name grains allowed on a gluten-free diet.
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- arrowroot - buckwheat - cassava - corn - flax - millet - nut flour/butter - quinoa - rice - sorghum - soy - tapioca
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Name possible benefits of a gluten-free diet.
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- heals GI tract - protects against liver and pancreatic disease - replaces B vitamins and minerals
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Name conditions that may benefit from a gluten-free diet.
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- autism spectrum disorders - autoimmune thyroid disease - type 1 diabetes - IBS
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Recognize environmental and lifestyle factors that play a role in the development of diabetes.
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- age and race - overweight - physical inactivity - impaired fasting glucose or glucose tolerance - history of gestational diabetes - hypertension - high cholesterol - PCOS
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Recognize major complications of diabetes.
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- brain: TIA, cerebrovascular accident, cognitive impairment - heart: CAD, MI, CHF - kidney: albuminuria, kidney failure - eye: retinopathy, cataracts, glaucoma - nerves: peripheral or autonomic neuropathy - extremities: ulceration, gangrene, amputation
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Recognize lifestyle factors that may be used to manage diabetes and why.
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- adequate sleep and exercise - stress management - weight loss - treatment of underlying conditions - consistent monitoring
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Name dietary patterns that are useful for prevention of diabetes and why.
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Bernstein diet: - high protein - low carb - low glycemic - calorie restriction
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Name supplements or functional foods that are useful for treatment of diabetes and why.
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- cinnamon: decrease TAGs, LDLs, cholesterol - Konjac root (glucomannan): increases satiety - gymnema: decrease taste of sugar - fenugreek, brewer's yeast, bittermelon, prickly pear: blood glucose control
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Name supplements or functional foods that are useful for prevention of diabetes complications and why.
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- alliums, niacin, EPA/DHA: CV support - tumeric, dandelion, milk thistle: liver support - legumes: high fiber for GI and stabilize blood sugar - grape seed extract, dark berries: eye support - evening primrose oil: nervous system support
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Name the functions of thyroid.
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- production of thyroid hormone T4 - production of calcitonin for calcium regulation - control of BMR, mitochondria, cholesterol/TAGs, carb and fat metabolism, heart rate and pressure, and GI motility
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Name foods/ nutrients/categories to avoid or restrict with low thyroid function and why.
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- goitrogens (raw): cruciferous vegetables, almonds, soybeans, peanuts and pine nuts, millet, sweet potatoes - cigarette smoke
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Name foods/nutrients/categories to treat high thyroid function and why.
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- increase goitrogens to 3-4 servings daily - antioxidants - carnitine: antagonist of thyroid hormone - calcium and magnesium: CV symptoms - high dose iodine under close supervision
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Name diet changes to improve adrenal function and why.
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- decrease caffeine and sugar - increase antioxidants - protein-rich breakfast - low glycemic
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Name nutrients to improve adrenal function and why.
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- B vitamins, esp. 5 and 12 b/c depleted under chronic stress - vitamin C b/c used up by adrenals in high amounts - sodium, decrease in early stages and increase in later stages
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Name conditions associated with estrogen imbalance.
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- endometrial cancer - uterine leiomyoma - fibrocystic breast disease - breast cancer - liver cancer - CNS dysfunction - emotional changes - inflammation - fluid retention
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Name diet changes or nutrients to improve estrogen metabolism and why.
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- organic and hormone-free - moderate fat, emphasizing omega-3-FAs, olive oil, and flax - low saturated fat, sugar, alcohol, and caffeine - high fiber
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Name dietary sources of phytoestrogens.
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- alfalfa - flax seeds - sesame seeds - soy (tofu, tempeh, edamame, miso)
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Name the dosage range of dietary phytoestrogens and isoflavones recommended in an anti-estrogen diet.
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- soy: 25 g daily - isoflavones: 60 mg daily
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