Ruminant Anesthesia – Flashcards

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question
List the anesthetic agents (that she thinks are important) that have an MRL and therefore and be used in food animals (6)
answer
xylazine Detomidine Azaperone Procaine Isoflurane Various NSAIDs
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What is bloat/regurgitation of ruminants during anesthesia primarily due to?
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positioning >> won't occur unless the animal is *recumbent*
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Which sedative can make regurgitation happen more often in ruminants? Rarely?
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rarely = xylazine Often = acepromazine IF ALSO RECUMBENT
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What is the pathogenesis of bloat/regurigitation in ruminants during anesthesia?
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esophageal spincter is covered with fluid (below the fluid line) so gas is kept in
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Why is a standing cow not susceptible to bloat (in comparison to a recumbent one)
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ruminal fluid line below the esophageal sphincter
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In cattle, many procedures are performed with what level of anesthesia?
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under local anesthesia +/- sedation
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In sheep and goat, many procedures are performed with what level of anesthesia?
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general anesthesia
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If a cow dies with NSAIDs in its body, why is it such a big problem? How can you kinda skirt around it?
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NSAIDs kill birds that will eat the carcass Meloxicam however is not too toxic to vultures
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Can you use opioids in ruminants?
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yes, but it's off label
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Why is it bad to OD ruminants on opioids?
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they tend to get excited
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Which sedative agents are commonly used in adult cattle (3)? Which ones are licensed?
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xylazine = licensed Detomidine = licensed Acepromazine = NOT LICENSED
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What is the big benefit to using an a2 adrenoceptor agonist to sedate something?
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they can be reversed if necessary (eg using atipamezole)
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TQ: What sedative are cattle ESPECIALLY sensitive to and its very effective in?
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xylazine Especially in comparison to horses and dogs
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How much xylazine should you use in a cow as compared to a horse?
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1/10th of the dose *lower dose IV and epidural*
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What route is not licensed to give xylazine in cattle?
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IV
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When is the use of xylazine contraindicated in cattle? Why?
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*last trimester* of pregnancy Increases uterine contractions and vascular resistance and is abortogenic
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Xylazine has breed sensitivity issues for what spp?
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cattle, sheep, goats
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Major side effect of xylazine in cattle
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*hypoxia* >> basically it causes pulmonary edema in the lungs
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How much detomidine should you give to a cow as compared to a horse?
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same amount Doesn't have the dose sensitivity species difference that you see in xylazine
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Why is detomidine useful for standing surgery
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less hyponotic than xylazine therefore the cow is less likely to go down
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What anesthetic is better when you have a pregnant cow: xylazine or detomidine?
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detomidine - less uterine effects
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Why do you get hypoxia when using a2 in ruminants? (3)
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pulmonary cellular infiltration Pulmonary edema Positional (the least important factor)
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What sedative choice would you use in a pregnant ruminant?
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acepromazine/morphine
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What sedative choice would you use to enhance sedation in ruminants?
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acepromazine/morphine
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What major problem comes when anesthetizing ruminants after giving acepromazine/morphine?
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likely to then regurgitate
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Can you use chloral hydrate in ruminants?
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yes BUT not licensed
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What dilution and volumes of chloral hydrate do you use in ruminants?
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use as dilute as possible And infuse a large volume
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What route of administration must you give chloral hydrate?
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IV Very irritating if given outside of a vein
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What are the potential complications of using general anesthesia in a cow? (5)
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regurgitation Bloat Salivation Respiratory depression Hypoxemia
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Why is salivation a problem in the generally anesthesized cow?
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they naturally produce a lot of saliva but this time they aren't swallowing
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What level of anesthesia can cows do active regurgitation? When?
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under light anesthesia Maybe under intubation
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What are the major reasons a cow will passively regurgitate (4)
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deep anesthesia *positioning* Drug specific Disease specific = HIGH RISK IN A DA
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How long should you deprive a cow of food and water before surgery in order to *prevent regurgitation*?
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starve = 12-24 hours Withhold water = 12 hours
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What should you do if a cow regurgigates while under
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keep the head elevated (if you can) and intubate ASAP
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How can you prevent bloat in a cow during anesthesia? (3)
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withhold highly fermentable food 24 hours prior *Minimize anesthetic time* Continue monitoring post operatively
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Why are cows so prone to bloat during anesthesia?
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accumulate CO2 and methane in the rumen still But no eructations wile unconscious
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Cow bloat during anesthesia messes with what?
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ventilation >> causes hypoventilation
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How can you stop bloat during anesthesia in a cow?
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stomach tube Trochar in an emergency
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Salivation by a cow during surgery can contribute to?
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respiratory obstruction
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TQ? DO NOT administer what drug if you see a cow salivating during anesthesia? Why?
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*Atropine >> induces ileus and increases viscidity of saliva*
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How can you avoid a cow inhalaing its saliva during anesthesia?
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intubate
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Ketamine mixed with what drugs can provide a good alternative sedative for cows?
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midazolam Guaifenesin
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Why is thiopental or other hypnotics not given much to sedate cows?
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they metaboliza most hypnotic type sedatives very rapidly
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Which drug is a cow more likely to regurgitate with: ketamine or thiopental?
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thiopental
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What are the 3 ways to ET tube a cow? What things are needed with each way?
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manual palpation - 'guard' the cuff or it'll get damaged on teeth Visual = need a large and expensive laryngoscope Blind = VERY deep anesthesia
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'Triple drop' for cows? Why?
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guaifenesin/ketamine/xylazine Anesthetic maintenance
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Why do we only use 5% guaifenesin in a triple drip in cows?
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they're more sensitive to the hemolysis effects of guaifenesin than horses
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What should you still be doing during anesthetic maintenance that you did in induction?
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intubate and give oxygen
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Because cows have very shallow and fast breathing during anesthetic maintenance, what should you be prepared to do?
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change the CO2 absorber because it'll get used up very quickly
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Why is it preferable to be able to do mechanical ventilation in cows?
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spontaneous ventilation and it tends to be rapid and shallow
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How do you position a cows head during anesthesia and why?
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always keep head elevated and mouth below poll so that saliva, regurgitation drains downwards and out
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Eye position in ruminants when they're very light?
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eyes are down
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Eye position in ruminants when at a good level of anesthesia
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eyes are central
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HR, RR for cows under anesthesia
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HR = 45-80 RR = 15-30
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What is the tidal volume of cows?
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small!!! 4-6 ml/kg
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Where do you tend to measure direct BP in cows?
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auricular artery
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ETCO2 in cows
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tends to be very high
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Anesthetic drugs cause what complication in cows?
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central depression
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Due to recumbency in cows during anesthesia, what happens?
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ventilation/perfusion mismatch
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Why do cows show hypoventilation during anesthesia?
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low chest wall and pulmonary compliance Abdominal pressure on the diaphragm (esp if preggo) Expanding rumen
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Because cows are so prone to hypoventilation and/or hypoxemia during anesthesia you should be prepared to
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mechanically ventilate
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How do you place cows in anesthetic recovery?
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sternal recumbency and well supported BEFORE extubation
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How long should you maintain the ET tube in cows? NB?
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maintain ET tube in situ until chewing/swallowing starts May chew off and inhalate tube o_O Some gags can be used to prevent this from happening
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What should you give to cows while recovering from anesthesia?
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supplementary oxygen
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Goats are particularly sensitive towhat anesthetics?
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local aesthetics Or just easily overdosed
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Sheep are more likely to get pulmonary edema wih what drugs?
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xylazine or other a2 agonists
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What predisposes sheep to have a worse time during anesthesiia than cows?
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more likely to have a preexisting respiratory disease
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What anesthetic advantages to small ruminants have over cattle?
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smaller size so can keep sternal and its practicable to use propofol Many practicable IV injection sites
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IVcatheterization in goats and sheep jugulars
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goats = easy to hit BUT DON'T HIT THE CAROTID Sheep = very mobile skinn over the jugular so the catheter may pull out
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Why do you need good quality catheter for sheep and goats?
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all of their veins are very fragile
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Why are cephalic catheters in small ruminants advantageous
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non-mobile skin
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What are the main a2 agonists using in small ruminants?
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xylazine, medetomidne
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Why does our prof avoid a2 in the small rumis if possible?
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risk of pulmonary edema
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NB of using acepromazine in small rumis
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regurgitation if to be recumbent
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What benzos are used as sedatives in small rumis? Why do they work well?
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diazepam and midazaolam Benzos are so good because they almost work hynoptically
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What opioids are used as sedative agents in small rumis
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morphine, buprenorphine
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What drugs in ruminants can be used as induction agents but not maintenance agents due to their very rapid metabolism
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barbituates and propofol
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Even though mask induction is used in small rumis, what are they much more likely to do?
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regurgitate
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What is essential in order to intubate a small rumi
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laryngoscope
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What are the 2 ways you can intubate small rumis
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visual and blind
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What drugs make ET intubation in small rumis easier?
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'hypnotic' anesthesthetics rather than ketamine
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In order to intubate a small rumi, what may you need in order to place the tube into the trachea?
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a 'stiffener'
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Maitenance of anesthesia in small ruminants is achieved through
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inhalants mainly TIVA - barbituates TIVA - propofol TIVA - alfaxalone TIVA - ketamine combinations
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How should ruminants be placed during anesthetic recovery? Why?
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place in sternal recumbency in order to eructate
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Do not remove an ET tube in ruminants until
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they can maintain sternal recumbency
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Where is the best target for IV access in camelids?
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right jugular vein, high up
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Why is it difficult to thread a catheter in camelids?
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veins have valves
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Instead of hitting the jugular vein in a camelid, what might you hit instead because it's so close?
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carotid artery
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How think is a male camelids skin? Why do we care?
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up to 1 cm really hard to get IV access
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Besides the jugular, what are the next best veins to access in camels?
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cephalic or saphenous
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If you can't hit a vein in a camelid to administer anesthetics, what should you do?
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IM injection is generally a good idea
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Before nintubation of a llama/alpaca, what should you do?
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desensitize the larynx with lidocaine
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What is essential for the intubation of llamas and alpacas? why?
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intubation is difficult! need a guide wire and laryngoscope
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How long and wide should your ET tube be for a llama/alpaca?
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35-40 cm long 8-10 mm diameter wide
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Llama/alpacas are more or less sensitive to xylazine than other ruminants?
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less sensitive to xylazine
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What can you administer to improve the sedative and analgesia in llamas/alpacas?
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opioids
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During anesthesia, what problems are llamas and alpacas prone to?
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hypoxemia
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During anesthetic recovery, llamas and alpacas shhould be monitored for? what should they be given?
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monitor for respiratory obstuction supplement with oxygen
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When does rumination begin in calves/lambs/kids/creas? Therefore how do you change your anesthetic protocol?
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begins at 8-12 weeks old so therefore you shouldn't starve them for too long before that or else risk hypoglycemia
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What are the best sedatives for baby ruminants?
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diazepam/midazolam
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What gas inhalant is used for mask induction in baby ruminants?
answer
sevoflurane
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For short anesthetic procedures, what is the best combination to use for TIVA?
answer
xylazine/ketamine
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