Pulm-micro Answers – Flashcards
Unlock all answers in this set
Unlock answersquestion
| Signs of Streptococcus pneumoniae Pneumonia |
answer
| Rales, Dull Sounds CXR: Lobar Consolidation WBC: Elevated |
question
| Morphology of S. pneumoniae |
answer
| Gram (+) diplococci/laceletpairings |
question
| S. pneumoniae lab cues |
answer
| Catalase(-), Optochin Sensitive, Alpha-Hemolytic, Detergent/Bile Lysis |
question
| Diagnosis of S. pneumoniae |
answer
| Culture Latex Agglutination of Capsular Antigen Quelling Reaction |
question
| Nosocomial Pneumonias |
answer
| Staph aureus, Streptococcus pneumoniae, Pseudomonas aeruginosa, Legionella pneumoniae |
question
| Transmission of S. pneumoniae |
answer
| Endogenous or Respiratory Secretions |
question
| Suseptibility to S. pneumoniae |
answer
| Trauma, DM, Smoking, Alcohol, Chronic Lung Disease, Malignany, Chronic Antibiotics, Narcotics, Renal Failure |
question
| Pathology of S. Pneumoniae |
answer
| Inflamation, Edema and Pus Formation |
question
| Complications of S. Pneumoniae |
answer
| (#1)Otitis Media, (#1)Meningitis, Bacteremia, Sinusitis |
question
| S.pneumoniae Virulence Factors |
answer
| IgA Protease Pneumolysin Capsule: Higher density increases Virulence, 80 Serotypes, 23 cause 90% of pneumonias from S. pneumoniae |
question
| Immunity to S. pneumoniae |
answer
| Innate: C3b, Phagocytosis Adaptive: IgG(Phagocytosis), IgM(complement) |
question
| Treatment of S. pneumoniae |
answer
| Ampicillin/ B-lactams-> Fluroquinolones or Vancomycin 50% PBP Alterations |
question
| Prevention of S. pneumoniae |
answer
| Vaccine: 1)Susceptible (elder/Immunosupressed): 23 polysacciride Immunization 2)Children 7 Polysacchirides bound to protein |
question
| Strep pneumoniae Buzz Words |
answer
| Lobar Consolidation, Acute Onset, Shaking Chill, Pink/Red Sputum |
question
| Morphology of Klebsiella pneumoniae |
answer
| Gram(-) Rods |
question
| Epidemiology of K. pneumoniae |
answer
| Oral, GI |
question
| Virulence Factors of K. pneumoniae |
answer
| Capsule, endotoxin |
question
| Lab Diagnosis of K.pneumoniae |
answer
MBE, or Mackonkey agar, Biochem tests |
question
| Maconkey Agar Bacteria |
answer
| Klebsiella pneumoniae, E. cloi, Enterobacter |
question
| Presentation of K. pneumoniae Pneumonia |
answer
| Necrotizing Pneumonia with Currant Jelly Bloody Sputum |
question
| Morphology of Pseudomonas aeroginosa |
answer
| Aerobic, Motile, Gram(-) Rods |
question
| Virulence of P.aeruginosa |
answer
| Enterotoxin A: Adp-ribosylation of EF-2 Endo,Exo,Enterotoxins Hemolysin, Leucocidin, Preoteolytic Enzymes Capsule, Pilli |
question
| Epidemiology of P.aeruginosa |
answer
| Intestine, Skin, 15% of Nosocomial Pneumonias |
question
| Susceptibility to P.aeruginosa |
answer
| Extensive Burns, CF with Ventilator, Predisposition |
question
| Complications of P.aeruginosa |
answer
| Osteomyelitis, Bacteremia |
question
| Lab Characteristics of P aeruginosa |
answer
| Oxidase(+), Pneumocyanin, Pneumoverdin |
question
| Pseudomonas aeroginosa Treatment |
answer
| Susceptibility Test, followed by combo therapy |
question
| Morphology of Mycoplasm pneumoniae |
answer
| Small, Pleomorphic, coccobacillus, w/o cell wall |
question
| Mycoplasm pneumoniae Culture |
answer
| Complex Media: Sterols, Lipoprotein, 5% CO2 |
question
| Pneumonias that require a source for infection |
answer
| Legionella pneumonphila, Coxiella burnetii, Mycobacterium avium |
question
| Epidemiology of Mycoplasm pneumoniae |
answer
| 15% of Pneumonias, 50%of PAPs |
question
| Pathogenesis of M. pneumoniae |
answer
| Cytoadhesins PI with ROS prodution |
question
| Presentation of M.pneumoniae |
answer
| Nonproductive Cough,Patchy Infiltrate (CXR) 1-2wk incubation-> PAP-> 1-4wk Resolution Infectious after resolution |
question
| Lab Diagnosis of M.pneumoniae |
answer
| Antigen Serology Cold Agglutination Titer Culture: Fried Egg on Sterol,lpa,CO2 |
question
| Treatment of M.pneumoniae |
answer
| Doxacycline or Erythromycin |
question
| Morphology of Legionella pneumophila |
answer
| Gram(-) Rods |
question
| Lab Testing of L. pneumonphila |
answer
| Oxidase(+), Catalase(+) Culture on Buffered Charcoal Yeast Agar |
question
| Epidemiology of Legionella pneumonphila |
answer
| Water towers, Shower focets, Air conditioners Nosocomial, Biofilms, Amoebae Elderly |
question
| Presentation of L. pneumonphila |
answer
| Bronchitis-> Confluent Pneumonia/GI Symptoms-> Abcess-> Shock, DIC |
question
| Pathogenesis of Legionella |
answer
| Prevent Phagosome-Lysosome Fusion, Resist Oxidative Damage |
question
| Legionella with mild Walking Pneumonia |
answer
| Pontiac Fever |
question
| Transmission of Legionella |
answer
| source only |
question
| Lab Diagnosis of Legionella |
answer
| Culture BCYE EIA Urine: Picks up 80% Community strain, 20% of Nosocomial Strains Nucleic Acid: Future |
question
| Treament of Legionella |
answer
| Macrolides (Azithromycin), Fluroquinolones (Levofloxacin) |
question
| Immunity to Legionella |
answer
| IFN-gamma production |
question
| Control of Legionella |
answer
| Chlorine, Heat, Copper/silver agents |
question
| Presentation of Chlamydia Psittaci |
answer
| Bird Contact->PAP(w/ photophobia, and severe Headache) -> Consolidation -> 20% mortality |
question
| Diseases of Psittaci |
answer
| Psittacosis: Parrot Ornithosis: Non-Parrot |
question
| Diagnosis of psittaci |
answer
| Serology |
question
| Treatment of psittaci |
answer
| Tetracycline |
question
| Presentation of Chlamydia pneumoniae |
answer
| Otitis, Sinitus, PAPs |
question
| Epidemiology of C.pneumoniae |
answer
| 20% of Young Community Acquired Pneumonia |
question
| Diagnosis of C.pneumoniae |
answer
| IgG>512, IgM>16 |
question
| Epidemiology of Coxiella burnetii |
answer
| Sheep, Cows, Goats In milk, Placenta, Hydes, Feces, Urine |
question
| Presentation of burnetii |
answer
| PAPS-> Hepatitis/ Endocarditis |
question
| Disease of Coxiella burnetii |
answer
| Q Fever |
