Plagues and Pestilence 1 – Flashcards

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What is schistosomiasis?
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Bilharzia/Snail Fever/The Pharaoh's Plague
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What is the causative parasite of Bilharzia?
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Schistosoma
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Who discovered schistosomiasis? How?
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Theodor Bilharz discovered it in 1851 in blood vessels during an autopsy
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Cercariae
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A free swimming larva coming from the snail that carries Bilharzia
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Miracidium
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What hatches from the eggs that are laid by the adult schistosoma worm. Hatches in the human intestines
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Enlarged abdomen, bloody urine, fatigue
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symptoms of Bilharzia
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Three major historical bubonic plague pandemics
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Justinian Plague: 542-543

Black Death or Great Dying: 1346-1352

China: 1860s

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Effects of the black death on public health
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Origin of the word quarantine, the sick is the enemy, more power to the boards of health
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Who discovered the black death, and how?
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Alexander Yersin, identified the germ in 1894
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The scientific name for the Black Death
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Yersinia pestis
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Major scientists that developed the germ theory
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Louis Pasteur, Alexander Yersin, Robert Koch
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Causative agent of the black death
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Yersinia pestis (pathogenic bacteria)
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Rats and fleas
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Vectors of the black death
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Yersinia outer proteins
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prevent bacteria from being ingested by the host white blood cells
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Three plagues caused by Yersinia pestis;
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Bubonic, septicemic, pneumonic
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War fever, prison fever, ship fever
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Alternate names for Typhus
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Overcrowdings, low nutrition, poor hygiene practices
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Conditions associated with typhus
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headache, pink rash, chills, confusion, fever, muscle pain
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symptoms of typhus
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proved that typhus is carried/transmitted by lice
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Charles Nicolle
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Rickettsia prowasekki
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microbe that causes typhus
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What is the difference between typhus and typhoid fever?
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Typhoid fever is caused by salmonella
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light microscopy
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light passes through specimen, then through magnifying lenses
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Tetracycline/Doxycycline
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treatment for typhus today
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Anopheles
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species of mosquito that carries malaria
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What did Ronald Ross discover about malaria?
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It is transmitted by sparrows
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Causative agent of malaria
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Plasmodium species
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How can you catch malaria?
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Bitten by a mosquito
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How is malaria prevented?
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killing mosquitoes, killing larvae, education, treatment
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Anthony van Leeuwenhoek
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made the first microscope by grinding down a piece of glass
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spontaneous generation
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the belief that organisms can appear from nonliving material
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three scientists who disproved spontaneous generation
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Francisco Redi, John Tyndall and Louis Pasteur
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three domains of microbes
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bacteria, eucarya, archaea
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bacteria
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specific shapes, rigid cell walls, multiply by binary fission
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eucarya
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membrane-bound nucleus, internal organelles, single or multicellular
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archaea
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similar to bacteria in all but: cell wall makeup is different, and they are found in extreme environments
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algae
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found near surface waters, rigid cell wall, contain chlorophyll
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fungi
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gets energy from organic materials, found wherever organic materials are present, diversely single celled or multicellular
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protozoa
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single celled, larger than procaryotes, complex, nonrigid cell wall
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virus
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protein coat surrounding nucleic acid, must have host machinery to replicate, kill host cells
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viroid
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simpler and smaller than viruses, short piece of RNA
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prokaryote
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single celled organism consisting of a prokaryotic cell; members of the domain bacteria and archaea
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prokaryotic cell
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cell type characterized by the lack of a membrane-bound nucleus
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eukaryote
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organism composed of one or more eukaryotic cells
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eukaryotic cell
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cell type characterized by a membrane-bound nucleus
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capsule
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distinct thick gelatinous material that surrounds some microorganisms
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chemotaxis
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directed movement of an organism toward or away from a certain chemical
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peptidoglycan
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macromolecule that provides rigidity to the cell wall; found only in bacteria
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gram negative bacteria
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cell wall composed of a thin layer of peptidoglycan surrounded by an outer membrane
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gram positive bacteria
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cell wall composed of a thick layer of peptidoglycan
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pili
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cell surface structures that generally enable cells to adhere to certain surfaces
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resolution
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the ability of a microscope to clearly separate two objects that are very close together;
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phase-contrast microscope
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Amplifies differences between refractive indexes of cells and surrounding medium
Uses set of rings and diaphragms to achieve resolution

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interference scope
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causes specimen to appear three dimensional
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dark-field microscope
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inverts image (appears bright on a dark background)
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