Pharmacology EAQ Chapter 46 – Flashcards
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Which category of drugs is sometimes called the rubicins?
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Anthracycline drugs
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For which clinical signs should the nurse monitor in a patient receiving busulfan? Select all that apply.
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cough, shortness of breath, abnormal breath sounds
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For which potential adverse effect should the nurse monitor in a patient taking cisplatin?
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ototoxicity
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Which adverse effects are expected in a patient using bleomycin? Select all that apply.
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Pneumonitis, Pulmonary Fibrosis
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Which adverse effect is expected in a patient receiving busulfan?
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Pulmonary fibrosis
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A patient on cisplatin develops pneumonia. Which drug would be added to the prescription to promote patient safety?
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Amoxicillin
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A patient who is on doxorubicin gains 6 pounds in a week of treatment. What is the possible cause?
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Heart failure
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Which drug, referred to as nitrogen mustard, was the first antineoplastic drug invented?
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Mechlorethamine
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A patient who is on cisplatin reports hearing roaring sounds. What term does the nurse use to document this condition?
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ototoxcity
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A patient is receiving chemotherapy. Which signs and symptoms should the nurse monitor to assess myelosuppression in the patient?
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Anemia, blood loss, and thrombocytopenia
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Which process refers to the insertion of a drug molecule between the two strands of DNA molecule, blocking its transcription?
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Intercalation
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A patient is on chemotherapy with alkylating agents. Following periodic lab work, the nurse instructs the patient to use a soft-bristled toothbrush and to avoid activities that may increase risk of injury. What could be the reason behind the nurse's instructions?
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The patient has developed thrombocytopenia.
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Which drug acts an estrogen receptor modulator?
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Tamoxifen
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Which instructions are included in the basic assessment of a cancer patient who is on antineoplastic drugs? Select all that apply
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Assess the patient's medication history. Analyze baseline neurologic functions. Order laboratory reports before starting the treatment.
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Which miscellaneous antineoplastic medication is beneficial in treating chronic myeloid leukemia?
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Imatinib
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The nurse advises a patient who is on cisplatin to avoid extreme cold conditions and cold objects. Which adverse effect is the nurse trying to prevent in the patient?
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Peripheral neuropathy
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Which medication reduces the risk of renal toxicity associated with cisplatin?
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Amifostine
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For which complications should the nurse monitor in a patient receiving bevacizumab? Select all that apply.
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Proteinuria, hypokalemia, hypertension
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A patient on chemotherapy develops swollen joints and severe pain. Which diagnostic test would the provider likely order for the patient?
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Serum uric acid
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Which adverse effect is associated with anastrozole?
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Vasodilation
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The nurse will suspect which type of cancer in a patient receiving tamoxifen ?
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Breast cancer
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Which side effects would the nurse expect in a patient receiving estramustine? Select all that apply.
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Edema, anorexia, leg crramps
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A patient administered cisplatin during chemotherapy developed nephrotoxicity. Which actions should the nurse take before administering the drug?
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Hydrate the patient with intravenous fluids.
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When providing education to a patient undergoing antineoplastic drug therapy, which signs and symptoms would the nurse teach the patient that indicate an oncologic emergency that requires immediate notification of the health care provider? Select all that apply.
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Blood in urine, bleeding gums, swollen tongue, new & persistent cough
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The nurse is caring for a patient with cancer. On reviewing the patient's prescription, the nurse finds that the patient has been prescribed a cytotoxic antibiotic that causes pulmonary fibrosis. Which medication was prescribed for the patient?
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Bleomycin
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A patient treated with phenytoin 300 mg tid developed adrenal corticoid cancer and was prescribed mitotane. The primary health care provider replaces phenytoin with levetiracetam. What is the reason for doing this?
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Mitotane reduces serum phenytoin concentrations.
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The nurse is counseling a patient on antineoplastic drugs. Which instructions should the nurse emphasize during the session?
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Maintain hygienic conditions. Avoid spicy, irritating, or gas-forming foods. Perform self-assessment of blood pressure and pulse rate regularly.
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Which drug is classified as an antineoplastic hormone?
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Estramustine
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The nurse finds that a patient who had been administered carmustine intravenously (IV) has developed extravasation. Arrange the steps in the sequence that the nurse should follow to manage extravasation.
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-Stop the drug infusion immediately -Aspirate residual from the catheter -Infuse antidote after consulting guidelines -Rest the affected limb -Document the extravasation carefully
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Which drug acts through intercalation and can cause pulmonary toxicity?
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Bleomycin
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A patient who is on doxorubicin is prescribed dexrazoxane by the primary health care provider. What could be the rationale behind prescribing dexrazoxane?
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The drug protects the heart.
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Which treatment is contraindicated in patients undergoing radiation therapy?
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Administering cyclophosphamide
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On which interventions should the nurse focus for patients who have thrombocytopenia and are administered alkylating agents? Select all that apply.
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Prevent infection. Monitor urinary patterns. Prevent injuries or blood loss.
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Which antineoplastic drug works by inhibiting the action of the enzyme Bcr-abl tyrosine kinase and is used in the treatment of chronic myeloid leukemia?
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Imatinib
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Which antineoplastic drug class is effective for the treatment of both solid and hematologic malignancies?
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Alkylating agents
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A patient who was intravenously administered a cytotoxic antibiotic complains of a burning sensation and pain at the site of infusion. The nurse observes swelling at the site and immediately administers cryotherapy to the patient. The condition of the patient gradually improves. Which drug was responsible for the complications?
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Doxorubicin
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A patient is administered antineoplastic agents. The primary health care provider prescribes allopurinol to the patient after referring to the patient's blood reports. What could the reports have indicated?
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Increased uric acid levels
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A patient who is on bleomycin has a history of emphysema. Which laboratory test should be prescribed to ensure patient safety?
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Pulmonary function test
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The nurse administered carmustine intravenously to a patient, which caused extravasation. Which antidote should the nurse use to prevent tissue damage in the patient?
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Sodium Bicarbonate