Pharmacology 105 Exam #1

What is the study of the physiochemical properties of drugs and how they influence the body called?
A) Pharmacokinetics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacology
C) Pharmacodynamics

Pharmacokinetics involves the study of
A) physiologic interactions of drugs.
B) distribution rates among various body compartments.
C) interactions between various drugs.
D) adverse reactions to medications.
B) distribution rates among various body compartments

How can drugs exert their action on the body? (Select all that apply.)
A) By interacting with receptors
B) By making the cell perform a new function
C) By inhibiting the action of a specific enzyme
D) By altering metabolic chemical processes
A, C, and D)

What is an alternate name for biotransformation of a drug?
A) Absorption
B) Dilution
C) Excretion
D) Metabolism
D) Metabolism

A drug given by which route is altered by the first-pass effect?
A) Sublingual
B) Subcutaneous
C) Oral
D) Intravenous
C) Oral

Drug half-life is defined as the amount of time required for 50% of a drug to
A) be absorbed by the body.
B) exert a response.
C) be eliminated by the body.
D) reach a therapeutic level.
C) be eliminated by the body

Which action will increase the absorption of a medication administered intramuscularly?
A) Applying cold packs to the injection site
B) Lowering the extremity below the level of the heart
C) Administering the medication via the Z-track method
D) Massaging the site after injection
D) massaging the site after injection

Highly protein-bound drugs
A) increase the risk of drug-drug interactions.
B) typically provide a short duration of action.
C) must be administered with 8 ounces of water.
D) have a decreased effect in patients with a low albumin level.
A) increase the risk of drug-drug interactions

To achieve the most rapid onset of action, by which route will the health care provider administer the medication?
A) Subcutaneously
B) Intravenously
C) Intramuscularly
D) Intrathecally
B) Intravenously

Patients with renal failure would most likely have problems with drug
A) excretion.
B) absorption.
C) metabolism.
D) distribution.
A) excretion

What is the ratio between a drug’s therapeutic effects and toxic effects called?
A) Tolerance
B) Cumulative effect
C) Therapeutic index
D) Affinity
C) therapeutic index

Which factors will affect the absorption of orally administered medications? (Select all that apply.)
A) Presence of food in the stomach
B) pH of the stomach
C) Patient position upon intake of medication
D) Form of drug preparation
E) Time of day
A, B, D, E,

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