Pharmacology 105 Exam #1 – Flashcards

A drug given by which route is altered by the first-pass effect? A) Sublingual B) Subcutaneous C) Oral D) Intravenous

Drug half-life is defined as the amount of time required for 50% of a drug to A) be absorbed by the body. B) exert a response. C) be eliminated by the body. D) reach a therapeutic level.

Which action will increase the absorption of a medication administered intramuscularly? A) Applying cold packs to the injection site B) Lowering the extremity below the level of the heart C) Administering the medication via the Z-track method D) Massaging the site after injection

Highly protein-bound drugs A) increase the risk of drug-drug interactions. B) typically provide a short duration of action. C) must be administered with 8 ounces of water. D) have a decreased effect in patients with a low albumin level.

To achieve the most rapid onset of action, by which route will the health care provider administer the medication? A) Subcutaneously B) Intravenously C) Intramuscularly D) Intrathecally

Patients with renal failure would most likely have problems with drug A) excretion. B) absorption. C) metabolism. D) distribution.

What is the ratio between a drug's therapeutic effects and toxic effects called? A) Tolerance B) Cumulative effect C) Therapeutic index D) Affinity

Which factors will affect the absorption of orally administered medications? (Select all that apply.) A) Presence of food in the stomach B) pH of the stomach C) Patient position upon intake of medication D) Form of drug preparation E) Time of day