PE Chapter 12 – Flashcards

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Cardiovascular disease is the __ __ killer of both men and women in the U.S. since 1900, with the sole exception of 19__, when a pandemic flu killed more people.
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number one, 18
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More than __ million Americans- __ out of every three adults- suffers from one or more types of cardiovascular disease
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83, one
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CVD is affected by __ and __.
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heredity, lifestyle
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Chronic diseases are illnesses that are __, do not resolve __, and are rarely __ completely.
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prolonged, spontaneously, cured
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Cardiovascular disease includes diseases of the heart such as, high blood __, __ heart disease, heart __, __, and congenital cardiovascular defects.
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pressure, coronary, failure, stroke
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CVD kills __ people each year and one every __ seconds, as well as 2200 lives each week.
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815,000, 39
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__ to __ percent of people under age 40 have CVD, and for those over 40, the rate is about __ percent. After age 60, three in four people have it.
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nine, fifteen, forty
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One in three adult women has CVD, and __ women than men die from it. Only from ages __ to __ do more men have CVD.
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more, 20, 39
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55,000 more __ than __ have strokes each year.
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women, men
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The cardiovascular system is a network of __ and __ through which blood flows as it carries oxygen and nutrients to all parts of the body.
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organs, vessels
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The cardiovascular system contains the __, __, __, __, __, __.
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heart, arteries, arterioles, veins, venules, capillaries
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The heart is __-sized and contracts 100,00 times each day. It pumps the body's __ quarts of blood.
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fist, six
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The heart has four chambers: two upper ones called __, which receive blood from the rest of the body, and the lower two, called __, which pump it out again.
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atria, ventricles
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The four steps of blood in the heart: __ blood enters the __ atrium; it then goes to the right ventricle through the __ __. From here it gets to the lungs to receive oxygen. Next, it goes to the __ atrium, and from there to the left ventricle, and from there to the rest of the body via the __.
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deoxygenated, right, pulmonary artery, left, aorta
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The __ __ is in the right atrium and regulates the pace of one's heartbeat.
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sinoatrial node
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__ is thickening and hardening of the arteries, and is also the __ contributor to CVD globally. It is caused by deposits of __, __, cellular __, and the clotting material __.
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Antherosclerosis, biggest, fat, cholesterol, waste, fibrin
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Antherosclerosis is an example of __ __ disease, and the substance that builds in the arteries is called __. __, an abnormally high level of lipids in the blood, contributes to this.
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coronary artery, plaque, hyperlipidemia
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When the heart is starved for oxygen, the condition is called __.
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ischemia
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When atherosclerosis occurs in the arms, feet, calves, and legs causing nearly complete blockage, it is called __ __ disease.
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peripheral artery
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__ __ disease is the greatest killer, accounting for __ in six deaths in the US.
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coronary heart
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785,000 __ heart attacks and 470,000 __ attacks happen each year, and another 195,000 __ heart attacks (without signs and symptoms) occur each year.
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new, recurrent, silent
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__ __, or heart attack, involves a section of the heart which suffers permanent damage because its normal blood supply has been blocked.
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myocardial infarction
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Symptoms of a heart attack include __ pain or pressure, arm, neck, or jaw pain, difficulty __, excessive __, __, __, and loss of __.
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chest, breathing, sweating, nausea, vomiting, consciousness
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The __ following a heart attack is crucial. __ percent of people die in this time frame.
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hour, 40
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What to do in the event of the heart attack: __ __ as soon as the person shows any signs of a heart attack. Do not drive yourself or a family member. You may need to try __.
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call 911, CPR
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These are the types of cardiovascular disease: __, __ heart disease, __ __, __, __ heart failure, and __.
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atherosclerosis, coronary, angina pectoris, arrythmias, congestive, stroke
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Stroke warning signs include __, __, __ loss, __, and severe __.
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numbness, confusion, vision, dizziness, headache
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Hypertension is most prevalent among __ __.
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African americans
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__ __ occurs when there is not enough oxygen to supply heart muscle, resulting in chest pain or pressure. __ percent of people ages 25-45 will have it, and __ percent of men and __ percent of women experiencing symptoms by age 65.
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angina pectoris, 2, 13, 11
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To treat angina pectoris, __ __ blockers, __, and __-blockers are used.
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calcium channel, nitroglicerides, beta
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__ are an irregularity in heartbeat, which occurs when the electrical impulses in your heart do not work correctly. A fast beat is __, and a slow one is __. Irregular patterns is __. The latter is possibly fatal.
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arrythmia, tachycardia, bradycardia, fibrillation.
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Congestive heart failure is __ common, with ___ new cases each year.
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very, 670,000
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Causes of CHF include heart injury from a number of CVD risks, such as uncontrolled high __ __, __ fever, __, __ __, and other cardiovascular problems. In some cases __ treatment and __ for cancer can contribute.
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blood pressure, rheumatoid, pneumonia, heart attack, radiation, chemotherapy
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In CHF, weakened heart muscles respond poorly to strain, impairing __ __ and causing fluid backup. This causes congestion in __ __.
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blood flow, body tissues
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CHF can be treated with __ that releive fluid accumulation, drugs such as digitalis which increase the heart's pumping action, and __, which expand blood vessels.
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diuretics, vasodilators
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A stroke is also called a __ accident. They can be __ (caused by plaque formation that narrows vessels or by a clot) or __ (due to weakening of a blood vessel that causes it to bulge or rupture).
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cerebrovascular, ischemic, hemorraghic
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An __, in which a blood vessel bulges or ruptures, is the most well known of hemorrhagic strokes.
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aneurism
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Strokes are often preceded by __ __ attacks (TIA's) which cause dizziness, weakness, temporary paralysis, memory loss, blurred vision, nausea, headache, slurred speech, and other physiological reactions.
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transient ischemic
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The top number is __ blood pressure, which refers to the pressure of blood in the arteries when the heart muscle contracts, sending blood to the rest of the body. The bottom number is __ blood pressure, which is the pressure of blood on the arteries when blood is re-entering heart chambers.
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systolic, diastolic
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Hypertension is __ as likely overall in women. In those under 45, however, __ are most likely to develop it. In those 65 and older, though, it affects more women.
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twice, men, women
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When only systolic blood pressure is high, it is called __ systolic __, and this is the __ common type of high blood pressure in older Americans.
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isolated, hypertension, most
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CVD risk factors include __, __, lack of __ __, high __, and high __ __ all increase your risk. Together, they are called __ risks.
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obesity, smoking, physical exercise, cholesterol, blood pressure, cardiometabolic
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Hypertension can lead to slowing of __ function and increased __'s risk.
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cognitive, Alzheimer's
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Different names for combined cardiometabolic risks: syndrome __, insulin __ syndrome, and __ __.
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X, resistance, metabolic syndrome
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Metabolic syndrome risk factors include __ obesity, elevated __ fat, low levels of __, elevated __ __, elevated fasting __, and high levels of __-reactive __.
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abdominal, blood, hdl, blood pressure, glucose, c, protein
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__ percent of people ages 20-39 qualify for MetS, along with __ percent of those over 60.
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20, 52
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To reduce CVD, one of the most powerful modifiable risks to avoid is __. Others are to cut back on __ fat and cholesterol, monitor levels of __, __, maintain healthy __, to control __ and __.
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smoking, saturated, cholesterol, exercise, weight, diabetes, stress
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Smoking accounts for 1 out of every __ deaths, and smokers are __-__ times more likely to get CHD. It __ risk of stroke.
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5, 2-4, doubles
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__ percent of children ages 3-11 are exposed to secondhand smoke.
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60
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By smoking, a person exposes himself to __ and other harmful __ in the smoke. The former causes increased heart rate, heart output, blood pressure, and oxygen use: in other words, the __ works harder.
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nicotine, chemicals, heart
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If one stops smoking, risk __ quickly. After a year, risk of HD drops by __ percent.
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declines, 50
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One modifiable risk for heart disease is cutting back on __ and __ __.
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cholesterol, saturated fats
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__ percent of your cholesterol level is predetermined, and is produced by the __ and other cells. The other __ comes from __. It is in this latter area that improvement can be made, resulting in less risk for CVD.
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75, liver, 25, food
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A meal high in saturated or trans fats can put the body at greater risk for heart attack within __. Even a __ percent reduction in these results in __ percent less risk for heart disease.
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hours, 10, 30
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High __ levels and low __ levels puts one at risk of heart disease (cholesterol types).
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ldl, hdl
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__ are gaining attention, as they are found in people with high cholesterol and heart problems. Levels increase as people get older and heavier. When the body consumes too many calories, it accumulates in the __ __.
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triglicerides, fat cells
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A baseline cholesterol test, or __ panel, should be taken at age __ and every __ years after that. It measures LDL, HDL, trigliceride, and total cholesterol levels.
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lipid, 20, 5
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A baseline cholesterol test should be taken after a __ hour fast when the person is well __ and has avoided caffeine.
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12, rested
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Men over age 35 and women over 45 should have their lipid profile checked __.
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annually
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LDL is __ associated with CVD risk than is total cholesterol.
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more
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Body weight __ play a role in CVD, especially by straining the heart by forcing it to push blood through more __. __ fat is most dangerous, and losing even 5-10 pounds can be significant.
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does, capillaries, abdominal
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Even modest levels of low-level activity __ modify CVD risks. The more, the better! It increases __ levels and lowers __.
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can, HDL, triglicerides
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Those with diabetes are __-__ times more likely to die from heart disease. __ percent of people with diabetes do indeed die of it.
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2-4, 65
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People with diabetes may experience deterioration of blood vessels in the __ and __.
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eyes, extremities
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Hypertension is a risk for CVD: at systolic 140-159 and dystolic 90-99 indicates __ stage hypertension: above 160 systolic and 100 dystolic is __ stage.
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first, second
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Those who are stressed may turn to __, be impatient and __: these issues of unresolved stress turn out to be risk factors for CVD, resulting in three times the risk of hypertension, CHD, and sudden cardiac death.
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smoking, hostility
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Nonmodifiable risks for CVD include __, __, __, and __.
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race, heredity, age, gender
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Inflammation may play a major role in __ development. The injured vessel walls are more prone to __ formation. Several factors such as cigar smoke, high blood pressure, high LDL's, diabetes, certain forms of arthritis, and exposure to toxins can cause it.
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atherosclerosis, plaque
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Exposure to Chalmydia pneumoniae (respiratory infection) helicobacter pylori (ulcers), and cytomegalovirus (herpes) can cause __, which can contribute to heart disease. __-__ proteins are an indication of this.
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inflammation, C-reactive
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__ is an amino acid that, when present in high amounts, is related to higher incidence of CVD. __ acid may break it down, and thus is likely good for you.
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homocysteine, folic
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Heart super-foods include fish, __ oil, whole __ and __, plant __ and __, nuts, chocolate, and green tea.
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olive, grains, fiber, sterols, stanols
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African Americans are more likely to have hypertension and also have a higher risk of stroke. The rate of hypertension in African Americans is among the __ in the world.
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highest
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Common medicines used for CVD: statins, which lower __ __ levels; ace-inhibitors, which cause blood vessels to __ and thus lower blood pressure; beta-blockers, which reduce blood pressure by reducing __.
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blood cholesterol, contract, epinehrine
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Techniques for diagnosing heart disease: __ (ECG), __, __ __ tomography, __ __ imaging, ultrafast __ tomography.
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electrocardiogram, angiography, positron emission, magnetic resonance, computed
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An __ is a record of the electrical activity of the heart. It may involve a stress or nuclear stress test: this provides a good indicator of potential heart blockage or blood flow abnormalities.
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electrocardiogram
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In __ (cardiac catheterization), a needle-thin tube called a catheter is threaded through heart arteries, and a dye is injected, and an X-ray is taken to determine blockages.
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angiography
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In __ __ __, powerful magnets are used to look inside the body and help physicians identify damage from a heart attack and evaluate disease of larger blood vessels.
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magnetic resonance imaging
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In __ __ __, a super-fast form of x-ray desinged to evaluate bypass grafts, diagnose ventricular function, and measure calcium deposits, is used.
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ultrafast computed tomography
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In __ __ __, a test is used which measures the amount of calcium-containing plaque, a marker for atherosclerosis buildup.
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cardiac calcium score
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Coronary bypass surgery with a graft (CABG for short), means taking a __ __ from another area of the body (most likely the saphenous vein in the leg or internal thoracic from the chest) and implanting it to __ an area of the heart that was damaged.
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blood vessel, bypass
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Angioplasty carries __ risks than CABG. In it, a catheter is threaded through blocked arteries, then is __ to open them. A __ is then added to hold them open. Though highly effective, these can lead to inflammation and tissue growth.
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fewer, inflated, stent
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__ may help heart disease. It has protective blood-thinning qualities, but many dangerous side effects.
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aspirin
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Cancer is the __ leading cause of death in Americans of all age groups, but five-year survival rates are __ dramatically from the early 1990s
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second, up
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__ is responsible for about 30% of all cancer deaths. Poor __ and exercise habits account for another 30% of cancer deaths
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tobacco, diet
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Evidence supports that most cancers could be prevented by simple __ changes.
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lifestyle
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__ is the name given to a large group of diseases characterized by the uncontrolled growth of abnormal cells.
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Cancer
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Tumor: a __ mass of tissue that grows more rapidly than surrounding tissue and serves no purpose.
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neoplasmic
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Benign tumor: (noncancerous) mass of cells enclosed in a __ that prevents their penetration of other tissues. Generally __ unless they grow and obstruct or crowd out normal tissue.
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membrane, harmless
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__ tumor: (cancerous) mass of cells that can invade surrounding tissues through __. Every case of cancer begins as a change in a cell that allows it to grow and divide when it should not.
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malignant, metastizing
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The only way to tell between malignant and benign tumors is through __.
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biopsy
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Metastasizing cells emit claw-like protrusions that disrupt __ and __ in cells. This produces mutant cells
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RNA, DNA
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Nearly 76% of cancers are diagnosed at ages __ and over.
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55
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Lifestyle risks for cancer include exposure to environmental __ such as sunburns and chemicals; __ use; alcohol and __ use; poor __; physical __; and obesity.
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carcinogens, tobacco, drug, nutrition, inactivity
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__ use is the biggest risk for cancer: it is responsible for 1 in __ deaths, __ percent of cancer deaths, and __ percent of lung cancer deaths.
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tobacco, 5, 30, 87
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Smoking is is associated with increased risk of __ cancer types, especially lung, nasal, mouth, kidney, bladder, stomach, and acute myeloid leukemia cancers.
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15
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A high BMI (25 and up) is a strong indicator of cancer risk, especially of the __, __, cervical, and __ for women, and __ or __ cancers for men.
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breast, uterine, ovarian, prostate, stomach
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Women who gain 55 pounds after age 18 have a __ percent greater risk of breast cancer compared to those who maintain their weight.
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50
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Obesity in men puts them at a __ times higher risk for gallbladder and endometrial cancers.
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5
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Sleep disturbances, diet, or a combination of factors may weaken the body's __ system, increasing susceptibility to cancer.
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immune
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Hereditary risk factors for cancers include __ predisposition, __, and genetic __.
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genetic, oncogenes, susceptibility
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Oncogenes are typically __, but factors such as age, stress, exposure to carcinogens or viruses, and exposure to radiation.
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dormant
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Some cancers, especially __, __, colon, prostate, ovaries, and __ lung cancers, seem to run in families: in other words, people are genetically predisposed.
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breast, stomach, lungs
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The Breast Cancer Susceptability genes are __ and __.
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BRCA1, BRCA2
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These are all hormonal/reproductive factors. Early menarch, late __, not having __, Having children __ in life, recent use of __ __ pills, __ replacement therapy, and opting not to __ feed.
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menopause, children, late, birth control, hormone, breast
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__ prescribed for relieving menopausal symptoms contributes to cancer risks and to provide fewer benefits.
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estrogen
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Workplace risks account for only a small percentage of cancers: however, they must be considered. __ is one of the most potent risks, and __, chromate, and chemicals such as benzene, __, and vinyl chloride are all proven carcinogens.
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asbestos, nickel, arsenic
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Working with __ tars or __ exposes you to occupational risks of cancer.
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coal, inhalants
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Ionizing radiation increases one's risk of cancer. It can come from __-rays, __ rays, and __ radiation (UVB: the only kind proven to cause cancer). Nuclear exposures have indicated that high-level exposure to IR may cause cancer. The __ and __ are particularly vulnerable.
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X, cosmic, ultraviolet, thyroid, marrow
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Chemicals in food can contribute to cancer, such as these: __ __ (in red meat to give color and to preserve), __ (formed when the body digests the above). The former has not been banned because it kills clostridium botulism.
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sodium nitrate, nitrosamines
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Over 25% of all malignancies in the United States are caused by __, __, and __.
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viruses, bacteria, parasites
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Cell phone radiation and other, similar types of energy are __ in cancers of the neck, head, brain, and leukemia.
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suspected
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Rates of cancers related to infection are much __ in developed countries.
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higher
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__ B and C may prime the __ for cancer, stimulating cancer growth there.
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hepatitis, liver
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Nearly __ of women with cervical cancer have evidence of human papillomavirus (HPV) infection.
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all
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__ form in epithelial tissues (covering body surfaces and lining most body cavities), and are the most common type of tumor. These can effect the skin and mouth as well as mucus membranes. The mestastize through the lymph and circulatory systems and form solid tumors.
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carcinomas
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__ occur in the mesodermal or middle layers, such as bones, muscles, and connective tissues. They metastize through the blood in the early stages of disease. They are __ common but __ virulent than carcinomas. It forms solid tumors.
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sarcomas, less, more
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__ develop in the lymphatic system and metastize through it. __ disease is an example. It forms solid tumors.
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lymphomas, hodgkins
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__ is cancer in the blood-forming parts of the body, particularly the bone marrow and spleen. It is nonsolid and characterized by an increase in __ __ cells.
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leukemia, white blood
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Lung cancer is the __ cause of cancer deaths for both men and women in the United States, killing an estimated 156,940 Americans in 2011. __% of all lung cancers could be avoided if people did not smoke.
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leading, 90
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More women have died since 1987 from lung cancer than from breast cancer, despite reductions in smoking rates. There is growing concern about the number of __, particularly young __ and those of low __ status, who pick up the habit.
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youth, women, socioeconomic
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There is concern about the people who have never smoked yet represent __% of those with lung cancer: they were exposed to __ smoke, __ gas, __, __ smoke, and aerosolized oils caused by __.
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15, secondhand, radon, wood, cooking
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Symptoms of lung cancer include persistent __, blood-streaked __, chest __, and attacks of pneumonia and bronchitis.
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coughing, sputum, pain
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Treatment for lung cancer includes __, __ therapy, and __. The first is the treatment of choice if the cancer is localized.
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surgery, radiation, chemotherapy
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Survival rates for lung cancer are low after 1 year, at __ percent overall. The 5 year survival rate overall is only __ percent.
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41, 16
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Breast cancer is the __ __ cause of cancer death for women after lung cancer.
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second leading
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Incidence rates of breast cancer declined about __% between 2002 and 2003, but these did not continue even though __ use declined significantly.
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7, hormone
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Mammograms detect __ of breast cancers, but are not foolproof. This is why __-__ is recommended.
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90, self-examination
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Treatments for breast cancer include __, radical __, and combinations of __ and __. Selective estrogen-receptor modulators such as tamoxifen and raloxifene, which work by blocking __, show promise.
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lumpectomy, mastectomy, chemotherapy, radiation therapy, estrogen
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The five-year survival rates for breast cancer have risen from 80% to __% today. However, these rates vary widely depending on __ it is detected and upon whether it has __.
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98, when, spread
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The incidence of breast cancer __ with age. Family history of cancer, menstrual periods that started __ and ended __, __ after menopause, use of __ contraceptives or __ therapy, never having children or having them late in life, consuming __, and __ are all risk factors.
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increases, early, late, obesity, oral, hormone, alcohol, inactivity
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Colorectal cancers are the __ most common cancer in men and women. __% of cases are in the colon and __% in the rectum. __% are preventable.
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third, 72, 28 90
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Symptoms of colorectal cancers are nonexistent in the early stages: in later stages, they include __ in the stool, changes in __ habits, and bleeding from the rectum.
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blood, bowel,
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Only __% of Americans over 50 get the most basic test for colorectal cancers, the at-home fecal occult blood test. Colonoscopy or barium enemas are recommended for at risk populations and this age group.
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10
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Risk factors for colorectal cancers include family history, __, a family history of __, and inflammatory __ problems. Diets high in fat or low in fiber, smoking, __ lifestyle, high __ consumption, and low intake of fruits and vegetables may contribute.
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obesity, polyps, bowel, sedentary, alchohol
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These things may help prevent colorectal cancers: regular __, fruits and veggies, healthy __, and moderation in __ consumption. Milk and calcium, aspirin-like drugs, __ acid, selenium, and vitamin __ may also decrease risks.
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exercise, weight, alcohol, folic, E
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Treatment for colorectal cancers often includes __, __, and most recently __.
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radiation, surgery, chemotherapy
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Skin cancer is the most common form of cancer in the United States affecting over 1 __ people every year, or 1 in 5 adults.
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million
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The two most common forms of skin cancer are __ __ and __ __ carcinomas. They are highly curable. __ __ are very deadly.
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basal cell, squamous cell, malignant melnomas
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Basal and squamous cell carcinomas are a recurring annoyance that show up on the face, ears, neck, arms, hands, and legs. They may be __ bumps or __ patches. If they ooze, bleed, itch, or hurt, get them looked at.
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warty, scaly
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Melanomas show up as skin __ whose shape, size, and color __. They account for __% of skin cancer deaths, and the risk is ten times higher for caucasians, and is especially dangerous to __. 65-90% of these are caused by sun exposure.
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lesions, change, 75, men
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Melanomas can be identified by these ABCD characteristics: __, __ irregularity, __ (not uniform, black or bluish black, tan-deep brown, reddish black), __ (greater than 6 millimeters).
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asymmetry, border, color, diameter
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Treatment of skin cancer depends on its seriousness. In 90% of cases, __ is performed. __ (tissue destruction by heat) and __ (tissue destruction by cold), are also used. For melanomas, the nearby __ nodes may be surgically removed and radiation, and chemotherapy may be used.
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surgery, electrodessication, cryosurgery, lymph
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Risk factors for skin cancer include __ skin, light (blue, green, grey) eyes, burning __ tanning, __ readily, use no or expired sunscreen, have already had skin cancer or have a family history, and have had severe __.
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fair, before, peeling, sunburns
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The skin responds to sunlight by increasing in __ and by increasing the number of __ __ (melanocytes). This exposure kills skin cells that ward off __, priming it for cancer. It also causes wrinkling by damaging __.
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thickness, pigment cells, infection, collagens
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To avoid skin cancer, use SPF __ or greater sunscreen, and limit time outside when the sun is strongest (__-__).
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15, 10-4
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There is no such thing as a safe tan: in fact, salon lamps can emit both __ and __ rays. It also may not be calibrated correctly, leading to more or less exposure than desired.
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UVA, UVB
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Prostate cancer is the second leading cause of cancer deaths for men. 1 in __ men will be diagnosed with it, but only 1 in __ will die of it.
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6, 36
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Symptoms of prostate cancer include __ urine stream, difficulty starting or stopping, the urge to go frequently, __ in the urine, pain in the lower back, pelvis, or thighs.
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weak, blood
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Men over __ should have an annual digital rectal prostate examination, or the prostate-specific antigen test, which is a __ test. There are, however, severe limitations to the latter, as it may lead to unnecessary cancer treatments.
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40, blood
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90% of all prostate cancers are detected early, and over the past 20 years, the 5-year survival rate has increased from 67 percent to almost __ percent, and the 15-year rate is over __ percent.
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90, 76
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Chances of prostate cancer increase dramatically with age. More than 75% of diagnosis are on men over __. African American men are __ percent more likely to have prostate cancer. Those with a father or brother who has the disease have __ the risk (slightly higher for brother than father).
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65, 61, twice
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Eating more fruits and veggies, especially those with __, reduces prostate risk. To additionally reduce risk, follow __ guidelines and maintain weight.
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lycopene, dietary
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Ovarian cancer is the __ leading cause of death for women. It causes the most cancer deaths related to the reproductive system, because it often goes __ until the late stages.
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fifth, undetected
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Ovarian cancer symptoms include enlargement of the __, digestive disturbances especially in women over __, fatigue, unexplained weight loss, changes in __ habits, and __.
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abdomen, 40, bowel, constipation
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Risks for ovarian cancer: family history, not getting __, and use of __ drugs.
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pregnant, fertility
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To prevent ovarian cancer,use __ __, adhere to a low-__ diet, have __ children, and __-__.
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birth control, fat, multiple, breast-feed
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Women over __ should have a cancer-related checkup every year.
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40
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The __ cancer is diagnosed, the better. To detect it, __ __ __ (MRI), __ __ scan (CT scan) are used.
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magnetic resonance imaging, computed tomography scan
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MRI's use the vibrations of __ in the body, mapped on a computer screen, to find cancer. CT scans use __-__ to reveal a tumor's shape and more.
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atoms, X-rays
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Radiation (works by stopping cell growth and destroying malignant cells) and chemotherapy are used to treat cancer. The latter is necessary whenever the cancer has __.
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spread
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Radiation and chemotherapy, together or apart, have side effects including __, nutritional deficiencies, __ loss, and general __. Some healthy cells are destroyed in the process, and damage to cardiovascular and other systems is significant.
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nausea, hair, fatigue
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Promising areas of cancer research include __, which enhances the body's own defenses; __-__ vaccines, which combat abnormal cells; __ __ to increase the patient's immune system; and substances that block cancer-causing events along the __ __. Finally, __ __ research has proved controversial.
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immunotherapy, cancer-fighting, gene therapy, cancer pathway, stem cell
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