pathogenic bacteria – Flashcards

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Staphlococcus aures

A.Morphology

B.Cultural characteristics

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A."grape"like gram positive spheres

B.grow on simple media,yellow pigment,

can tolerate high salt,and catalase positive

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Staphylococcus aures virulance factors
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Protein A which binds to wrong end of ab,

and staph has a capsule

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Staphylococcus aures enzymes
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A.coagulase

B.Hyaluronidase

C.Staphylokinase

D.Lipase

E.Beta-lactamase

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Staphylococcus aures toxins
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A.exfoliatoxins(skin slough)

B.Hemolysisn(rbc lysis)

C.pyrogenic toxin (fever)

D.Tokic shock syndrome

E.Enterotoxins(vegas nerve)

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Staphylococcus aures infections
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A.pimples,boils,carbuncles,urinary tract,impentigo,and scaled skin

B.Systemic

C.Bacteremia(in blood)

D.Endocarditis(Heart lining, valves)

E.Pneumonia

F.Osteomyelitis

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Streptococcus pyogenes

A.morphology

B.cultural characteristics

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A.spherical,found as diplococci,gram positive,

and catalase negative

B.Require complex media

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Streptococcus pyrogenes virulance

A.protein

B.capsule

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A.protein M (stops compliment fixation

B.Made of hyaluronic acid(same as ours)

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Streptococcus pyogenes virulence

A.Toxins

B.Enzymes

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A.pyrogenic toxin(scarlet fever),

Streptolysin(lysis of rbc,wbc,platelets)

B.Streptokinase(breaks clot)

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Streptococcus pyogenes diseases
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A.Pharyngitis(strep throat)

B.Scarlet Fever

C.Pyoderma(puss filled lesions)

D.Erysipeals(in lymph nodes)

E.Necrotizing Fasciits(flesh eating bacteria)

F.Rheumatic fever(autoimmune,attacks heart valves)

G.Glomerulonephritis(type III hyper,kidney damage

 

 

 

 

 

 

 

 

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Streptococcus pneumoniae virulance

A.capsule

B.toxins

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A.capsular polysacchsride(antphagocytic)

B.Pneumolysin

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Streptococcus pneumoniae disease
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A.leading cause of bacterial pnuemonia

B.Sinusitis(sinus infection with puss)

C.Otitis media(middle ear with puss)

D.Bacteremia(in blood)

E.Endocarditis(heart lining

F.Pnuemococcal meningitis(high rate of death)

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Streptococcus agalatiae pathology
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Babies get it coming down the birth canal
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Streptococcus agalactiae disease
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Newborns can get pnuemonia,meningitis, blindness,deafness,mental retardation

mothers can get childbirth fever

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Viridians Streptococcus disease
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Dental cavities,plaque
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Streptococcus Mutans group disease
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Produce organic acids that cause tooth decay
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Bacillus Anthracis cultural characteristics
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Aerobic to faculative anaerobic, endospore former
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Bacillus anthracis disease
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A.Pulmonary anthrax

             (wool sorters disease,inflammation of

tissue seperating lungs)

B.Cutaneous Anthrax

(causes malignant pustule,can become systemic,death)

C.Enteric anthrax(rare)

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Cloristidium perfringens disease
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A.Gas gangrene

B.food poisoning(diarrhea and abdominal pain)

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All clostridium tetani morphology
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A.motile

B.small

C.terminal endospores

D.obligate anaerobe

E.gram positive

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Clostridium tetani disease
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tetanus toxin binds to ihibitory neurotransmitters,muscles cannot relax,lock jaw, you die because your diaphram cannot relax
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Clostridium botulinum disease
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A.Food borne ingest toxin, toxin blocks muscle  contraction causes flaccid paralysis,die

B.Infant, spores are ingested bacteria starts to

grow rare cause of sids

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Lactobacillus

A.morphology

B.what is it used for

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A.gram positive,rods,non spore former

B.used to make pickles,yogurt,saurekrout

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Listeria monocytogenes morphology

 

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Gram positive,nonspore forming,coccobascillus

found everywhere

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Listeria monocytogenes pathology
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affects pregnant women, newborns can cross placenta

Intracellular parasite,binds to mac or epithelial cell and induces phagocytosis, uses lysteriolysin O to break down the cell, pushes into next cell hiding from the immune system, goes to brain

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Mycobacterium tuberculosis

A.morphology

B.cultural characteristics

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A.Acid fast,slender straight or curved rod,

thick waxy cell wall

B.Shortest generation time 300 minutes

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Mycobacterium tuberculosis

pathology (primary)

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inhalation(only need 10),Macs in alveoli phagocytize but cannot digest bacilli,bascilli reproduce inside mac and kill it,cell mediated response calls more macs and cycle repeats,forms a tight ball called a tubercle,caseous necrosis in center this becomes a stale mate forms ghon complex(calcium deposit)
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Mycobacterium tuberculosis

pathology A.(secondary)B.(dissemated)

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A.Mycobacterium break out of tubercle, infection now reestablished,spreads to other parts of lungs

B.carried to other parts of the body

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Mycobacterium tuberculosis

A.treatment

B.Epidemiology

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A.Must remain on meds for six months

B.Up to one third of population infected,risk factors overcrowding and smoking,can last up to 8 months on fomites,5 percent exposed to the disease catch it,50 percent die

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Mycobacterium leprae cultural characteristics
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Grows best at 30C,on footpads of mice, not on normal media
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Mycobacterium leprae disease
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A.Tuberculoid Leprosy(minor skin infection)

B.Lepromatous Leprosy(the bad one)

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Mycobacterium avium who does it affect?
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Aids patients
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Corynebacterium diptheriae virulence factors
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Toxin-Diphtheria toxin
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Corynebacterium diptheriae pathology
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Toxins get into cell by endocytosis,stops ribosome function killing cells
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Corynebacterium diphtheriae disease

A.respitory B.cutaneous C.systemic

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A.severe signs and symptoms,local pain,fever,oozing of fluid,formation of the psuedomembrane

B.Psuedomembrane on the skin

C.toxins can be released causing death to heart and nerve cells leads to coma and death

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Neissera

A.morphology

B.cultural characteristics

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A.gram negative,bean shaped cocci with fimbrae

B.Needs Thayer-Martin agar,best with 5%c02,

very susceptible to drying out

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Neissera gonorrhoeae pathology
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sexually transmitted breaks down iga,attaches to epithelial cells and induces phagocytosis by wbc`s then carried throughout body
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Neisseria gonorrhoeae disease

A.men

B.women

C.infant

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A.painful urination,puss discharge

B.mostly asymptomatic,attach to vagina and cervix can get to fallopian tubes causing infertility,ectopic pregnancy

C.Happens coming down birth canal,called

opthalmia neonatorum causes blindness

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Neissera gonorrhoeae

A.diagnosis

B.Treatment

C.immunity

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A.gram negative diplococcal found in puss

B.very resiliant,cephalosporan

C.no vaccine,antigenic variability,can get repeatedly

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Nesseria meningitids pathology
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spread on droplets,has polysacharide capsule that keeps it from being degested, carried throughout body by wbc,contains lipid A which causes fever,vasodialation,inflamation,and shock
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Neisseria meningitiidis disease
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Flu like symptoms,convulsions,arthritis,loss of hearing,and septicemia-petechiae(skin lesions)

spread by cramped living conditions

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name the six types of enterobacteriaceae
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A.coliform(e.coli)

B.Klebsiella

C.proteus

D.Salmonella

E.shigella

F.Yersinia

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What bacteria gives you really watery sometimes bloody diarreah?
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E.coli
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E.coli pathology
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oral fecal route,pili bind to epithelial cells,can produce enterotoxins in the intestines,uti normal flora in wrong place
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What are the four strains of E.coli
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A.Enterotoxigenic (diarrhea)

B.Enteropathogenic(comes together because of pili)

C.Enteroinvasive(invades intestinal cells like shigella)

D.Enterohemorrhagic(strain #0157:h7 causes

hemolytic uremic syndrome)

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Klebsiella pneumoniae what and who
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causes pnuemonia(destroys alveoli)

Alcoholics and aids

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What are the two types of salmonella
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S.typhi and S.typhimurium
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Salmonella typhus pathology
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oral fecal route, bacteria go thru the intestines to the blood, get phagocytized but not killed, carried to the spleen,liver,bone marrow,and gall bladder back to intestines then eats hole in intestines
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S.typhimurium pathology
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causes salmonellosis,found on eggs,passes thru stomach attaches to intestines,inserts protein into cell,induces phago by intestinal cells,reproduces in cell and kills it
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What bacteria causes green diarrhea than turns mucusy
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Salmonella typhimurium
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Yersina pestis disease
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Bubonic plague(spread by flea bites,goes to lymph

nodes and causefever and pain untreated causes bacteremia,causes coagulation of blood and

leads to gas gangrene)

Pneumonic plague(Spread by droplets,infects the lungs)

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Proteus mirabilis pathology
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motile bacteria that swim up cathaters creates kidney stones
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Shigella pathology
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goes to large intestine attaches to epithelial

cells and induces phag,reproduces in cells,

invades other cells,forms abcess,

does not invade blood

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What bacteria causes fibrous diarrhea

with agonizing pain?

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Shigella
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What are the two types of spirochetes?
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Treponema(syphilis)

Borrelia(lyme disease)

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Treponema pallidum pallidum

phases

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primary forms a chancre which is small painless

and red,lesions last 3-6 weeks then go away

Secondary rash all over body which does not

itch after several weeks it goes away

Latency no signs or symptoms

Tertiary stage get gummas all over tissues

found on nerve cells and in the brain

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Borrellia burgdorferi what and how
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Lyme disease

spread by deer tick

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Borrellia burgdorferi phases
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Phase one bulls eye rash,stiff neck,and severs fatigue

Phase two Meningitis,cardiac problems

Phase three Severe arthritis that can last for years

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Chlamydia Morphology
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Extremely small, obligate intracellular parasites
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Chlamydia Life cycle
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1.Elementary body attaches to host cell,get phag,

now in inclusion body

2.Inside the cell becomes a reticulate body,

reproduce by binary fission

3.Back to elementary bodies,cause cell lysis,

release elementary bodies

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Chlamydia psittaci disease
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Inhalation of elementary bodies from birds causes a flu like disease called parrot fever
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Chlamydia trachomatis A,B,Ba,C disease
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Spread by flies,eye disease causes blindness
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Chlamydia D,E,F,G,H,I,J,K disease
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Sexually transmitted,Nongonococcal Urethritis,Asymptomatic in women,opthalmia neonaterum
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Chlamydia trachomatis L-1,L-2,L-3

disease stages

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1.starts as a painless lesion that heals quickly

2.Causes the inguinal lymph nodes

to swell forms a bubo

3.Lymph nodes burst,constriction of urethra,elephantiasis,arthritis in white males

Condoms dont help

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Vibrio cholera pathology
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Eat contaminated food,toxin gets into cells causing the secretion of electroytes,water follows,causes rice water diarrhea 20-30 times a day,lose 10 -15 liters of water a day,can cause coma and death
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What bacteria causes rice water diarrhea?
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Vibrio Cholera
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Helicobacter pylori

A.morphology

B.pathogenicity

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A.highly motile flagella, gram

negative,slightly helical

B.oral fecal route, from cats

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Heliobacter pylori disease
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Formation of peptic ulcer,burrows through mucus,kills mucus producing cells,causing a weak spot
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Psuedomonas Aeruginosa disease
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Gets into wounds of burn patients and cystic fibrouses patients,very resistant to drugs
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