Ob/gyn 1, Chapter 41 part 1 (week 6) – Flashcards
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We assess the female pelvis for
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Size Texture Vascularity Structure; Homogeneity, Endometrium, Vagina and Cervix
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What are the 3 main pathologies of the vagina
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Vaginal cuff Gartner's Duct Cyst Imperforate Hymen
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When is a vaginal cuff seen in patients
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After hysterectomy
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The upper size limit of a normal vaginal cuff is
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2.1 cm without a cervix, more if cervical remnant
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If the cuff is larger than normal or it contains a mass it should be regarded with
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Suspicion for malignancy, especially in patients with a previous history of cancer
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What is the most common cystic lesion of the vagina
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Gartner's Duct Cyst
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What are the symptoms of Gartner's Duct Cysts
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None, they are usually an incidental finding
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Solid masses of the vagina are rare, what are they
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Adenocarcinoma Rhabdomyosarcoma
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What is the most common congenital abnormality of the female genital tract, resulting in what
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Imperforate hymen, resulting in obstruction
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Obstruction of the uterus and/or the vagina may result in an accumulation of fluid in the uterus and vaginal canal. Give the classifications of fluid
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Accumulation of fluid is Hydrometra Accumulation of blood is hematometra Accumulation of pus is pyometra
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If accumulation of fluid reaches the cervix, then we add _____ to the name
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Colpos i.e. Hydrometracolpos
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What does a patient with Imperforate hymen present with
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Abdominal/pelvic pain and distension Primary amenorrhea Palpable midline pelvic mass
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What are the 5 main pathologies of the cervix
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Nabothian cysts Cervical polyps Cervical stenosis Cervical Leiomyoma Cervical Dysplasia/Carcinoma
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How is cervical pathology detected
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The tissue posterior to the cervical canal is larger than the tissue anterior to the cervical canal
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What is the most common cervical finding
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Nabothian cysts
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What is another name for Nabothian cyst
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Epithelial inclusion cyst
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What are the symptoms of Nabothian cysts
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None, they are usually an incidental finding
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What is the usual status of women who have Nabothian cysts
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Menarchal - women of reproductive age
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How are Nabothian cysts formed
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The cervical canal is lined with glandular (Nabothian) cells that normally secrete mucus. The Nabothian glands may become filled with secretions
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Describe a Nabothian cyst
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- Discrete, round, fluid-filled, anechoic structures Usually less than 2 cm - May be multiple - Sometimes have internal echoes that may be caused by hemmorrhage or infection, which should be noted
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What is cervical stenosis
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Obstruction of the cervical canal at the internal or external OS
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What are the causes of cervical stenosis
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Radiation therapy Previous cone biopsy (or any biopsy) Postmenopausal cervical atrophy Chronic infection Laser Cryosurgery Cervical CA
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What does a patient with cervical stenosis present with
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Distended, fluid-filled uterus as a result of uterine secretions, fluid, pus, or blood
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What are the clinical presentations of cervical stenosis
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In postmenopausal women - asymptomatic In menarchal women - Abnormal bleeding Oligomenorrhea or amenorrhea Cramping Dysmenorrhea Infertility
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What is another name for Leiomyoma
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Myoma, Fibroid
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How often do fibroids occur in the cervix
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A small percentage
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What can be the result of a cervical leiomyoma
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Bowel or bladder obstruction
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If a cervical leiomyoma becomes pedunculated what might happen
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It could prolapse into the vagina
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What is cervical dysplasia
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The abnormal growth of cells on the surface of the cervix
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Is cervical dysplasia cancer
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No, but it is considered to be pre-cancerous
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Cervical dysplasia is grouped into 3 catagories
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Mild Moderate severe
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How is cervical dysplasia treated
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Treatment depends on the degree of dysplasia. - Mild dysplasia may go away on its own; possibly only needing careful observation by your doctor with repeat Pap smears every 3-6 months - Treatment for moderate and severe dysplasia may include a more invasive procedure
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What causes cervical dysplasia
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All causes are not known, but most cases of severe dysplasia and cervical cancer are caused by infection of the cervix with a persistent, high-risk strain of human papilloma virus (HPV)
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What is HPV
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A very common infection that is transmitted through sexual contact.
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How many women are affected by HPV
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Over 75% of sexually active women are thought to acquire the virus at one point or another. Over 6 million people become infected with HPV every year in the US, and approximately 50% of those infected are between the ages of 15 and 25
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What happens if a women acquires HPV and is not treated
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30-50% of cases of severe cervical dysplasia may lead to invasive cancer. The risk of cancer is lower for mild dysplasia
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What is the most common type of cervical cancer
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Squamous cell carcinoma
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Who is affected by Squamous cell carcinoma
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Women of menstrual age
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What is the best method of diagnosis for Squamous cell carcinoma
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Pap smear
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What are the symptoms of squamous cell carcinoma
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It is asymptomatic until it becomes advanced and is slow growing
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What are the symptoms in advanced squamous cell carcinoma
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Abnormal vaginal bleeding Pelvic pain Abnormal vaginal discharge
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Is ultrasound the preferred method of staging of squamous cell carcinoma
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No, CT and MRI are preferred
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What are the 2 main pathologies of the uterus
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Leiomyomas Arcuate Artery Calcification
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What is the most common gynecologic tumor and how common is it
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Leiomyomas Occuring in 20-30% of women over age 30
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Who is more likely to get leiomyomas
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African-American women are twice as likely as Caucasian women
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What are other names for Leiomyomas
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Myoma Fibroid
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What are leiomyomas composed of
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Spindle shaped smooth muscle cells with variable amounts of fibrous connective tissue; encapsulated in a pseudocapsule and separates easily from the surrounding myometrium
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Are uterine leiomyomas usually found in multiples
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yes
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Why do we rarely see leiomyomas develop in post-menopausal women
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They are estrogen dependant
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When a leiomyomas vascular supply is compromised it will degenerate into several different histologic subtypes such as
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Liquefaction Necrosis Hemorrhage Calcification
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During pregnancy leiomyomas can
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Increase in size
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Leiomyomas identified in the first trimester of pregnancy are associated with
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Pregnancy loss
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Most leiomyomas tend to stabilize or decrease in size in post-menopausal women because
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Lack of estrogen stimulation
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What reasons would there be for leiomyomas to grow in post-menopausal women
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Hormone Replacement Therapy Tamoxifen Possible malignancy
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What are the clinical indications for leiomyomas
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Uterine irregularity Uterine enlargement Sensation of pelvic pressure Pain Irregular bleeding (menorrhea) including: - menorrhagia - menometrarrhagia - Infertility Interference with vaginal delivery
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Uterine locations of myomas
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Submucosal Intramural Subserosal
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What is a submucosal myoma
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Displacing or distorting the endometrial cavity causing heavy or irregular bleeding, possibly infertility, and sponaneous abortion
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What is an intramural myoma
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The most common location of a myoma Confined to the myometrium, can possibly lead to infertility
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What is a subserosal myoma
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Projecting from the peritoneal surface of the uterus Sometimes pedunculated and appear as an extrauterine mass
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What is the sonographic appearance of a uterine myoma
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- Uterine enlargement - Irregular uterine wall contour - Heterogenous myometrial texture pattern - Usually hypoechoic, but can sometimes be hyperechoic - Calcifications can appear bright and cause shadowing - Sometimes demonstrate an area of acoustic attenuation without a discrete mass
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What does the sonographer do if they see a myoma
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Measure - Long, AP, Trans Multiple myomas should be numbered as you go through Measure all dimensions for each as you go Put color on each to assess vascularity
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How are myomas treated
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Treatment depends on size, location, and clinical issues: Surgical Drug therapy Endometrial ablation and surrounding small myomas Uterine artery embolization HIFU - High intensity focused ultrasound
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Surgical treatments of myomas include
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*Myomectomy - removal of myoma (reoccurance of 20-25%) *Hysterectomy - removal of uterus (curative but irreversible)
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Drug therapy treatments of myomas include
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Pain relievers Hormone therapy to supress the myomas
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Endometrial ablation and surrounding small myoma treatments include
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Radiofrequency Microwaves Freezing Heating
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What are the causes of uterine calcifications
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Myomas Arcuate Artery Calcification
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What is the most common cause of uterine calcifications
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Myomas
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Where is an arcuate artery calcification found
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In the periphery of the uterus
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What does a uterine calcification look like
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Focal areas of increased echogenicity with shadowing