Microbiology Parasitology minimals 2012 – Flashcards

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question
Mention a worm species for which ab ano ad os auto-reinfection is characteristic in childhood!
answer
Enterobius vermicularis    
question
Mention 2 worm species that migrate through the human lungs in the larval stage!
answer
Ascaris lumbricoides
Ancylostoma duodenale
Necator Americanus
Strongyloides stercoralis
question
Which 2 protozoa may infect the human foetus transplacentally?
answer

Toxoplasma gondii

Plasmodium species

question
What is the laboratory diagnosis of malaria?
answer

Giemsa stained blood smear

Thick smear to screen for the agent

Thin smear to identify the species

question
How long is the erytrocytic cycle of Plasmodium vivax and P. ovale?
answer
48 hours
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How long is the erytrocytic cycle of Plasmodium malariae?
answer
72 hours
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What is the causative agent of malignant malaria?
answer
Plasmodium falciparum
question
Mention an antimalarial drug active against hypnozoites!
answer
Primaquin
question
How can one diagnose the African sleeping sickness disease?
answer

Giemsa stained blood smear for direct demonstration

serology can be helpful

question
What are the causative agents of African sleeping sickness?
answer
Trypanosome brucei gambiense and rhodesiense
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How can one diagnose amebic dysenetery?
answer
Microscopic demonstration E.Histoloytica cysts and trophozoites in feces
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How can one diagnose Trichomonas vaginalis infection?
answer
Direct demonstration of protozoa in wet mount of clinical specimens (vaginal, urethral or prostatic secretions)
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How can one diagnose intestinal taeniasis?
answer
Demonstration of characteristic proglottis and eggs (ova) in faeces.
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How can one diagnose Hymenolepis infection?
answer
Demonstration of eggs in feces
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How can one diagnose Ascaris infection?
answer
Demonstration of eggs in feces
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How can one diagnose trichuriasis?
answer
Demonstration of eggs in feces
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How can one diagnose Enterobius infection?
answer

Demonstration of eggs from perianal  skin (scotch tape technique)

not from feces!

question
Mention 4 tissue infecting filarial nematodes!
answer

Loa Loa

Oncocerca vulvulus

Dracunculus medinesis

Wuchereria bancrofti

question
How is human Fasciola hepatica infection acquired?
answer

By eating aquatic vegetation containing encysted larvae

(rarly by eating raw sheep liver containing adult warms)

question
What disease is caused if humans are infected per os with Taenia solium eggs?
answer
human cysticercosis (encysted larvae in brain, eyes..)
question
How is human Trichinella spiralis infection acquired?
answer
By eating raw or undercooked meat containing encysted larvae
question
Mention 2 protozoa that are susceptible to metronidazol!
answer
Entamoeba histolytica Giardia lamblia Trichomonas vaginalis
question
What are the 3 modes of transmission for human Toxoplasma gondii infection?
answer
Eating undercooked meat containing tissue cysts,
Contact with cat feces containing oocysts
Transplacental transmission
question
Mention 2 helminths whose larvae enter the human body by penetratring the intact skin!
answer
Ancylostoma duodenale
Nectar americanus
question
Which developmental form of Echinococcus granulosus can occur in humans?
answer
Hydatid cyst
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What is the definitive (ultimate) host of Echinococcus granulosus?
answer
dog
question
Which species are the causative agents of malaria?
answer
Plasmodium vivax, P. ovale, P. malariae, P. falciparum
question
What is the definitive (ultimate) host of Plasmodium species?
answer
female Anopheles mosquito
question
What are the definitive, and the intermediate hosts of Taenia saginata, respectively?
answer
definitive host: human intermediate host: cattle
question
What is the infectious form of Strongyloides stercoralis?
answer
filariform larva
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What is the infectious form of Trichuris trichiura?
answer
embryonated egg
question
Which form of Taenia saginata is infectious for humans?
answer
cysticercus (in beef)
question
Is autoreinfection possible in Ascaris lumbricoides infection? If yes, when?
answer
No, the eggs must mature in the soil for several days to become infectious (embryonated)
question
Is autoreinfection possible in Strongyloide stercoralis infection? If yes, when?
answer
yes, in immunosuppression (for example: AIDS)
question
Is autoreinfection possible in Enterobius vermicularis infection? If yes, when?
answer
yes, eggs become infectious in a few hours, ab ano ad os autoreinfection may occur. (especially in children)
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