Test Questions on Micro Exam 3 – Flashcards
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Unlock answerstransformation is the transfer of DNA from a donor to a recipient cell: |
as naked DNA in a solution |
mutations arising from chance events in the environment are known as: |
spontaneous mutations |
ultraviolet light may induce a mutation by:
|
binding together adjacent thymine molecules on the DNA molecule |
the deletion or insertion of extra nucleotides during a chromosomal replication can lead to: |
a mutation due to a shift in the reading frame |
nitrous acid can cause a mutation by: |
converting DNA's adenine to hypoxanthine |
the ames test is most useful for: |
learning whether a chemical can induce a bacterial mutation |
which of the following does NOT apply to plasmids? they are essential for the growth of the cell they are composed of DNA they multiply independently of the chromosome they may pass from cell to cell in recombination the fertility factor is a plasmid |
they are essential for the growth of the cell |
the work of Avery MacLeod and McCarty is significant;because;it: |
called attention to the;involvement;of DNA in heredity; |
during conjugation a recipient cell might be converted to a donor cell by the: |
acquisition of the F factor |
transposons are movable genetic elements that: |
carry information for protein synthesis ; can move from one position on a chromosome to another position; |
the rolling circle mechanism of DNA replication takes place during: |
bacterial conjugation |
the competence of a bacterium refers to its: |
ability to take up DNA from the;environment |
you have carried out a conjugation and discovered that the recipient cells have almost all become donors, but that no;chromosomal genes have been transfered. the male cell in the original mating was an: |
F+ cell |
avery demonstrated that pneumonia cocci could take up DNA directly ;from the medium surrounding them. this is an example of: |
transformation |
in one form of DNA transfer in bacteria, the DNA is transfered from one cell to another in a bacteriophage. if all fragments of the bacterial chromosome are transfered with equal frequency, the process is referred to as: |
specialized transduction |
transposons are movable genetic elements that: |
carry information for protein synthesis |
all of the following are true of a point mutation except: if affects a base pair it may be a change to a different nucleotide; it may be a substituted nucleotide all of the above are true |
all of the above are true |
the competence of a bacterium refers to its ability to: |
take up DNA from the environment |
mutations arising from chance events in the environment are known as: |
spontaneous mutations |
which of the following enzymes would not be involved with excision repair? |
RNA polymerase |
all of the following are true about DNA repair;mechanisms;except: DNA polymerase proofreads DNA sequences nuclease enzymes perform damage repair activities mismatch repair involves replacing long sequences of DNA damage repair involves the excision of damaged DNA and replacement with the proper nucleotides ; |
mismatch repair involves replacing long sequences of DNA |
one of the Streptococcus pneumoniae;strains used by Griffith was called smooth because the cells: |
had a capsule |
during conjugation a recipient cell might be converted to a donor cell by the: |
acquisition of the F factor |
diphtheria-causing bacteria contain a prophage that codes for toxin produced during disease. this is a consequence of the phenomenon known as: |
lysogenic conversion |
a phage that does not establish lysogeny in its host is referred to as: |
lytic |
Streptococcus pyogenes;produces a protein that, anchored in the cell wall and cell membrane, allows the bacterial cell to adhere firmly to the pharyngeal tissue. this protein is called: |
M protein |
Streptococcus pyogenes is a: |
beta-hemolytic streptococcus |
erythrogenic toxin is: |
produced by;Streptococcus pyogenes and damages the capillaries |
a 1 year-old female was hospitalized with fever, lethargy and rash. Gram-negative, oxidase-positive cocci were cultured from her cerebrospinal fluid. her symptoms were caused by: |
Neisseria meningitidis |
a Corynebacterium diphtheria infection is characterized by: |
pseudomembrane formation in the respiratory tract |
the erythrogenic toxin expressed in strains of;Streptococcus pyogenes is responsible for: |
the skin rash |
in some cases of meningococcal meningitis, hemorrhagic lesion form in the adredal glands, causing hormonal imbalance. this condition is called: |
waterhous-friderichson syndrome |
Nosocomical infections are those that: |
are usually acquired in the hospital |
all of the following are possible methods of transmission for Q fever except: inhaling airborne dust particle consuming raw milk inhaling airborne droplets consuming contaminated meat |
consuming contaminated meat |
; ; transformation |
the uptake of a free;DNA fragment from the surrounding environment and the expression of the genetic information in the recipient cell |
; ; conjugation |
a recombination process in which two live prokaryotic cells come together and the donor cell directly transfers DNA to the recipient cell |
; ; conjugation pilus |
an apparatus used by the donor (F+) cell that contacts the recipient (F-) cell during conjugation |
; ; F factor |
a plasmid that contains about 100 genes most of which are associated with plasmid DNA replication and production of the conjugation pilus; (found in F+ cells) |
; ; transduction |
form of HGT requiring a virus to carry a chromosomal DNA fragment from donor cell to recipient cell |
; ; lytic cycle |
a cycle of bacteriophage replication in which the phage DNA penetrates the cell, destroys the host chromosome, replicates itself within the cell, and then destroys (lyses) the cell as new phages are released |
; ; lysogenic cycle |
phage DNA integrates within the chromosome by recombination, doesn't cause immediate lysis of cell |
generalized transduction |
when phage with chromosomal DNA infect a cell |
specialized transduction |
when a phage carries along some donor DNA as well as phage DNA and transfers both types of DNA to a recipient cell |
Strep. throat Streptococcal pharyngitis |
Red pharyngeal lining, patches of pus, pain on swallowing, enlarge tonsils and lymph nodes (upper resp) |
Diphtheria |
Mild sore throat, slight fever swelling in neck., toxin production damages organs (upper resp) |
Pertussis-whooping cough |
Cold-like symptoms, mucus accumulates, intense spasms of coughing (upper resp) |
Meningitis |
Membrane covering brain and spinal cord (meninges) become inflamed. Primary in children under age 4. Severe headache, sudden high fever, stiff neck. (upper resp) |
Streptococcus pyogenes |
aerotolerant anaerobes, gram+ cocci in chains virulence factors: beta-hemolytic, M protein, erythogenic toxin, streptokinase & hyaluronidase |
Streptokinase |
allows streptococci to escape from a fibrin clot |
Hyaluronidase |
dissolves glue holding cells together. Hyaluroincacid is a major constituent of the interstitial space between cells. |
Alpha-hemolyticstreptococci |
turn blood agar an olive-green color Due to partial destruction of the red blood cell in the medium. |
Beta-hemolyticstreptococci |
surrounded by clear, colorless zone Due to complete destruction of red blood cells. |
M protein |
–Located in the cell wall and pili of streptococci –Encouraged adherence to pharynegealtissue –Retards phagocytosis |
Scarlet fever |
–strep throat accompanied by a skin rash due to production of erythrogenic (“red forming”) toxin
|
prophage |
viral genome integrated into cell DNA |
Lysogenic Conversion |
Cells gain new properties, for example altered surface components, when they become a lysogenof a phage |
Rheumatic fever |
characterized by fever and inflammation of the small blood vessels –Complication of untreated Streptococcal pharyngitis. |
Glomerulonephritis |
Complications like rheumatic fever where damage to kidneys arises from body’s antibodies reacting with streptococcal antigens bound to the kidney -complication of untreated Streptococcal pharyngitis |
Erysipelas –skin infection |
reddish patches on skin often with high fever. Involves lymph nodes, may have pus filled lesions. Common faces of children. -complication of untreated Streptococcal pharyngitis |
Necrotizing fasciitis |
Very rareflesh-eating disease •Streptococcusbacteria spread deep within the fascia, fibrous sheets of connective tissue surrounding muscles and binding them to one another. •There extensive damaged occurs that –involves rise in body temp, –in the host the toxin and bacteria acts as a superantigen causing the immune system to contribute to the tissue damage |
Puerperal sepsis (Childbirth fever) |
Uterus becomes infected during the birth process with Streptococcus. |
Septicemia |
“blood poisoning”when streptococci gets into and spreads throughout the body through the blood system. |
Corynebacterium diphtheriae |
–Gram + , nonspore-forming club-shaped rods. –with lysogenic corynephage that contain the genes for an exotoxin production |
Bordetella pertussis |
encapsulated Gram negative cocobacillus •Virulence factors: –non-invasive but highly destructive to ciliated epithelium; •ciliaryaction is blocked by accumulations of dense masses of these bacteria in the trachea and bronchia. –endotoxin released upon bacterial cells death, and increases host’s cytotoxinaction causing the eventual loss of ciliated cells |
A Corynebacterium dipheria infection is characterized by: |
pseudomembrane formation in the respiratory tract |
the erythrogenic toxin expressed in strains of Streptococcus pyrogenes is responsible for: |
the skin rash |
In some cases of memingococcal meningitis, hemorrhagic lesions form in the adrenal glands, causing hormonal imbalance. This condition is called: |
waterhous-friderichson syndrome |
Nosocomical infections are those that: |
are usually acquired in the hospital |
All of the following are possible methods of transmission for Q fever except: -inhaling airborne dust particles -consuming raw milk -inhaling airborne droplets -consuming contaminated meat |
consuming contaminated meat |
all of the following are bacterial diseases of the lower respiratory tract except: -tuberculosis -legionnaires' disease -psittacosis -klebsiella pneumonia -pertussis (whooping cough) |
pertussis (whooping cough) |
; ; legionnaires disease is caused by a: |
gram-negative rod |
; cases of psittacosis may be acquired by: |
contact with infected parrots or;parakeets; |
Which of the following is not a symptom of lethal pneumonia: -fluid build up in the lung cavity -reduction of oxygen intake -death of lung tissue -increased elimination of carbon dioxide |
increased elimination of carbon dioxide |
; What is the agent of primary atypical pneumonia? ; |
Mycoplasma pneumoniae ; |
; Cases of Legionnaire's disease have been linked to bacteria which:
|
accumulate in standing water |
Describe Q fever |
a rickettsial disease associated with livestock animals |
penicillin is useless for the treatment of mycoplasma pneumonia becuase the causative organism: |
have no cell wall |
Which of the following agents do not produce a toxin? -boredetella pertussin -corynebacterium diptheriae -streptococcus pyogenes -mycobacterium tuberculosis -none, all produce toxin |
mycobacterium tuberculosis |
A patient has fever, difficulty breathing, chest pains, and fluid in the alveoli. Gram-positive cocci were isolated from the sputum. The patient most likely has: |
pneumonococcal pneumonia
|
based on where in the body the infection occurs, which organism does not belong with the others? -bordetella pertusis -corynebacterium dipththeriae -mycobacterium tuberculosis -steprococcus pyogenes |
mycobacterium tuberculosis |
the diagnosis of tuberculosis is aided by: |
recovery of acid-fast rods from the sputum |
bacteriophages have been located in a lysogenic relationship with the causative organisms of:
|
diphtheria and scarlet fever
|
serratia marcescens is currently considered to be a cause of: |
meningitis |
A child suffering from repeated bouts of a violent, high-pitched cough is brought to her physician's office. The physician is likely to diagnose the infection as: |
bordetella pertussis |
Streptococcus pyogenes;causes all of the following diseases, except: -strep throat -scarlet fever -pneumonococcal pneumonia -puerperal fever |
pneumonococcal pneumonia; |
A pleomorphic organism with no cell wall that causes a type of pneumonia is: |
Mycoplasma pneumoniae |
; ; Erythrogenic toxin is produced by: ; |
Streptococcus pyrogenes;and damages the capillaries |
; an important principal criterion for the diagnosis of meningococcal meningitis is: ; |
gram-negative diplococci in spinal;fluid ; |
; A pleomorphic organism with no cell wall that causes a type of pneumonia is: |
Mycoplasma pneumoniae |
Which of the following statements about "flesh-eating" streptococcus is incorrect? -it is caused by a Group A streptococcus -is also known as necrotizing faciitis because it travels along the fascia - it causes death in high number cases -it is considered a common complication of strep throat -it involves toxemia |
it is considered a common complication of strep throat |
What is the disease where symptoms include a sore throat, fever, and swollen neck glands? Normally, an individual experiences only one case in a lifetime because the immune system produces special antibodies, called antitoxins. |
scarlet fever |
; ; The material used in the pertussis vaccine consists of: ; |
acellular chemical extracts of Bordetella pertussis |
All of the following are bacterial diseases of the lower respiratory tract except: -tuberculosis -legionnaires disease -pertussis (whooping cough) -Klebsiella;pneumonia |
pertussis (whooping cough) |
What is an organism present in air and soil that has been a concern with cooked rice that has been standing at room temperature? ; |
Bacillus cereus |
; The incubation period for staphylococcal food poisoning is shorter than that for salmonellosis because: |
staphylococcal food poisoning is due to a toxin rather than growth of bacteria |
An enormous number of cholera bacilli must be present in contaminated food for infection to be established because: |
most bacilli will be destroyed by the stomach acid |
Clostridium perfringens has received;notoriety;in recent years as an important cause of: ; |
food poisoning |
all of the following describe typhoid fever except: -the causative organism is a gram-negative rod -human carriers harbor the causative organism -ulcers may form in the tissue of the intestine -the disease is common in barnyard animals -rose spots often occur on the body surface |
the disease is common in barnyard animals |
; Brucellosis is an occupational hazard of those who: ; |
work with dairy herds |
; antibiotics are of no value treating botulism because: ; |
the person is intoxicated rather than infected |
; poultry products are a likely source of infection by: ; |
Campylobacter jejuni |
all of the following apply to Clostridium botulinum;except: -it produces a high;molecular;weight toxin -it is a gram-positive anaerobic spore forming rod -it may be involved with SIDS -it is an important cause of disease in agricultural crops -it may be the cause of limberneck in poultry |
it produces a high molecular weight toxin |
; the important consideration in treating patients who have bacterial dysentery is: ; |
replacement of lost fluids |
; The most common cause of traveler's diarrhea is: |
Eschericha coli |
No diarrhea can compare with the extensive diarrhea associated with:
|
cholera |
most gastrointestinal infections are treated with: |
penicillin |
Bacterial intoxication differ from bacterial infection of the digestive system in that intoxications:
|
have shorter incubation times |
A 38 year old mad had onset of fever, chills, nausea, and myalgia. On April 29, he had eaten raw oysters. On May 2, he was admitted to a hospital because of fever and two circular necrotic lesions on the left leg. What is most likely the cause of the illness? |
Vibrio vulnificus |
True or false: Travelers to cholera regions of the world can be immunized against cholera.
|
true |
What is one of the most heat resistant exotoxins? |
the staphylococcus enterotoxin |
All the following conditions may be caused by Clostridium botulinum except: -a wound botulism -intestinal ulcers -fodder disease -infant botulism -limberneck |
intestinal ulcers |
Which of the following pairs is incorrectly matched? -beef...E.coli -delicatessen meats...listeria -eggs...clostridium botulinum -milk...Campylobacter -oysters...Vibrio E. Oysters -- Vibrio |
eggs...clostridium botulinum |
All of the following apply to shigellosis except: -recoverers generally become carriers -the disease is caused by Gram-positive coccus -waves of intense abdominal cramps occur some cases -most cases subside without complications -the causative organism can be located in stool specimens |
the disease is caused by a Gram-positive coccus |
All the following bacteria are recognized as causes of foodborne or waterborne infections except: -Bacillus cereus -Aeromonas hydrophila -Yersinia enterocolitica -Vibrio parahaemolyticus -Yersinia pestis |
Yersinia pestis |
After recovery from typhoid fever, the carriers may harbor the organism in their: |
gall bladder |
The last pandemic of Asiatic cholera |
is going on today |
What are R factors? |
extra-chromosomal elements that contain drug-resistant genes |
Minimal heating of food to __ degrees Celsius for ten minutes will destry botulism toxin. |
90 |
Botulism toxin acts by: |
inhibiting the release of acetlcholine |
Probably the most potent toxin known is produced by: |
Clostridium botulinum |
H.pylori can be detected by which of the following methods: -stool samples -breath test -blood culture -increased urea concentrations |
breath test |
All of the following statements about staphylococcal food poisoning are true except: -suspect foods are those not cooked before eating -it can be prevented by refrideration -it can be prevented by boiling foods for 5 minutes before eating -it is treated by replacing water and electrolytes -it is characterized by rapid onset and short duration of symptoms |
it can be prevented by boiling foods for 5 minutes before eating |
Which one of the following is not known to be a method for the transmission of brucellosis? -cheese made from unpasteurized milk -splashing milk into the eye -accidental passage of fluid through skin abrasion -the bite of a tick |
the bite of a tick |
After recovery from typhoid fever, the carriers may harbor the organism in their: |
gall bladder |
One of the most important factors in controlling foodborne and waterborne disease is to: |
educate people to methods of sanitation and personal hygiene |
The antibiotic ceftriaxon is used to treat: |
typhoid fever |
What disease can be spread by household pets like ducks, tortoises and iguanas? |
Salmenella enterica serotypes |
Which one of the following is not associated with E. coli 0157:H7? -rice water stools -hemorrhagic colitis -hemolytic uremic syndrome -colonic perforation |
rice water stools |
This is the most commonly reported bacterial cause of gastroenteritis in the US. The illness affects over 2.5 million people and causes about 100 deaths each year. |
Staphylococcus aureus |
A distinguishing feature of disease caused by Brucella species is the: |
alternating periods of fever and relief |
The gastrointestinal infection caused by Vibrio vulnificus is characterized by all of the following except: -epticemia -necrotic skin lesions -increased stomach acid production -severe abdominal cramps |
increased stomach acid production |
Anthrax may be acquired by all of the following methods except: -consumption of food from vacuum sealed jars -inhalation of airborne spores -contact with infected animals -consumption of contaminated meat -contact with animal products |
consumption of food from vacuum sealed jars |
The toxins produced by Clostridium tetani: |
induce controlled contraction of the muscle |
the symptoms of tetanus are due to: |
deep puncture wounds |
Which of the following describes the Yersina pestis: -an aerobic spore forming rod -an anaerobic gram-negative rod with bipolar staining -a gram-negative rod with bipolar staining -a gram-positive aerobic coccus displaying metachromatic granules -an aerobic spore forming rod |
a gram-negative rod with bipolar staining |
The primary mode of transmission fro Rocky Mountain spotted fever is: |
bite of an infected tick |
Epidemic typhus is likely to occur where sanitation is lacking and where hygiene is poor because: |
lice flourish under these conditions |
Which of the following pairs is not correctly matched for the gram reaction? -tularemia--gram-negative -anthrax--gram-positive -lyme disease--gram-negative -bubonic plague--gram-positive -tetanus--gram positive |
bubonic plague--gram-positive |
Leptospirosis may post a threat to those who: |
work with barnyard animals or household pets |
Two forms of disease associated with Listeria monocytogenes are |
fetal damage and meningitis |
Endemic typhus may be expected to occur where there are: |
extensive populations of rodents and fleas |
Anthrax may be treated with antibiotics because: |
anthrax spores germinated into vegetative cells |
Infections of muscle tissue due to Clostridium perferingens are accompanied by: |
gas in the muscle tissue |
Clostridium perfringens exists widely in the soil and in the spore form in the: |
intestines of many humans and animals |
Endemic typhus occurs sporadically in human populations because: |
fleas are not natural parasites of humans |
The lockjaw associated with tetanus arises from: |
generalized muscle stiffness in the jaw |
All of the following pairs of diseases and modes of transmission are correct except: - scrub typhus and the mite -trench fever and the louse -bubonic plague and the flea -endemic typhus and the mite -endemic typhus and the flea |
endemic typhus and the mite |
The large joints can become stiff and swollen with arthritis as a complication of: |
lyme disease |
The flea is important in the transmission of: |
Bubonic plague |
All of the following apply to lyme disease except: -the causative organism is Borrelia bugdorferi -transmission is by the Xenopsylla flea -the disease was unknown before the 1970s -treatment is possible with penicillin or tetracycline |
transmission is by the flea |
A zoonosis is a disease: |
transferred from animals to humans |
Woolsorter's disease is another name for: |
anthrax |
; A disease caused by a spirochete is: |
leptospirosis |
All of the following diseases are caused by spore forming organisms except: -anthrax -tetanus -gas gangrene -bubonic plague |
bubonic plague |
; An antitoxin is an affective treatment for: |
tetanus |
; One of the distinctive characteristics of bacteria causing bubonic plague is: |
bipolar staining |
; A disease communicated by respiratory droplets is: |
pneumonic plague |
; The organism that causes Rocky Mountain spotted fever is: |
Rickettsia rickettsii |
The rickettsial disease which shares with plague, smallpox and cholera the distinction of having caused pandemics that have significantly reduced the human population is: |
epidemic typhus |
When it grows in the dead, anaerobic tissue of a wound, Clostridium perfringens: |
produces large amounts of gas |
; A zoonosis is a disease: |
transfered from animals to humans |
; The "second most powerful toxin known to science" is produced by: |
Clostridium tetani |
; ; Another name for tularemia is: |
rabbit fever |
; A disease spread by ticks and causing skin ulcers is: |
tularemia |
-associated with rat infestations -due to gram-negative rod which shows bipolar staining -may develop into septicemic and pneumonic stages -organs fill with bloody black fluid; |
bubonic plague |
-symptoms caused by powerful endotoxin -sometimes called woolsorter's disease -common in cows and sheep but not dogs or cats -caused by gram-positive aerobic sporeforming rod -organism used to satisfy koch's postulates |
anthrax |
-transmitted by ticks -due to a species of rickettsia -accompanied by a maculopapular rash -crusted boil like lesions on skin -diagnosis by well-felix reaction |
Rocky Mountain spotted fever |
-accompanied by contractions of the body's muscles -immunization rendered by injection of toxoid -vaccine included in the DTaP series -transmitted by anaerobic soilborne spores |
tetanus |
The organism of gonorrhea is rarely contracted: |
from a dry surface such as a toilet seat |
What disease can be transmitted to the fetus from an infected pregnant female? |
syphilis |
The organism of leprosy belongs to the same genus as: |
tubercle bacillus |
The normal microbiota of the adult vagina consist primarily of: |
lactobacillus |
What is trachoma? |
a chlamydial disease of the eyes |
All of the following are characteristic signs of secondary syphilis except: -flat wart-like skin lesions -gummae -swollen lymph glands -patchy loss of hair and eyebrows |
gummae |
Infection due to Haemophilus ducreyi may be identified by the isolation of: |
gram-negative rods from the genital papules |
Which of the following pairs is mismatched? -yaws--gram-negative cocci -gohorrhea--gram-negative cocci -chancroid--gram-negative rod -syphilis--gram-negative spirochete |
yaws--gram-negative cocci |
What is not a cause of nongonococcal urethritis? -chlamydia -mycoplasma -neisseria -ureplasma |
neisseria |
Nosocomical diseases are: |
acquired during hospitalization |
Species of Baceroides: |
inhabit the large intestines and feces of most individuals |
The chancre is a painless, circular, purplish ulcer associated with: |
primary syphilis |
Alpingitis, a possible complication of gonorrhea, is observed as a: |
blockage of the fallopian tubes |
The similarities of organisms and symptoms have led many microbiologists to believe there is a relationship between: |
yaws and syphilis |
A man had fever, malaise, and a rash on his chest, arms and feet. He also had an ulcer on his penis two months earlier. What stage of the disease is the patient in? |
secondary |
The greatest single cause of blindness in the world is: |
neonatal gororrheal optalmia |
A newborn's eyes are treated with an antibiotic when? |
always |
; What infection is caused by S. aureas? |
pimples, stys, boils, and carbuncles |
A 17-year-old male has pus-filled;cysts;on his face and upper back. Microscopic examination reveals gram-positive rods. This infection is caused by: |
Propionibacterium acnes ; Propionibacterium acnes |
Among the most common opportunistic bacteria that can cause nosocomical disease are all of the following except: -enterobacter aerogenes -mycobacterium leprae -pseudomonas aeroginosa -serratia marcescens |
Mycobacterium leprae |
Staphylococcus aureus;has been linked to all of the following conditions except: -impetigo contagiosum -toxic shock syndrome -bejel and pinta -scalded skin syndrome -boils and carbuncles |
bejel and pinta |
; ; Pseudomonas aeruginosa;is an: |
endogenous organism that causes burn infections |
; One of the difficulties in controlling gonorrhea is the fact that: |
50% of female infections may be asymptomatic |
; ; Gummas are: |
lesions, which destroy with elastic tissue and weaken major blood vessels |
; ; Chlamydia trachomatis causes: |
nongonococcal urethritis |
; Pseudomonas aeruginosa;is a severe problem in burn infections. This is due in part to the fact that: |
the bacterium has developed resistance to many antibiotics |
; Acute nectrotizing ulcerative gingicitis (NGU) is another name for: |
trench mouth |