MBG 2400 Study Cards – Flashcards

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polymorphism
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the occurrence of something in different forms among the members of a population or colony, or in the life cycle of an individual organism
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- Pleiotropy
- Epistasis
- Linkage
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Factors affecting independence and F2 ratios
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Pleiotropy
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one locus affects more than one trait
eg White cat= WW or Ww
W allele also causes deafness
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Epistasis
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alleles at one locus affect the expression of alleles at a different locus
eg. coat colour in labs
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linkage
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two or more loci are on the same chromosome
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Hardy-Weinberg Equilibrium
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seen in a LARGE, RANDOM MATING population in the ABSENCE of MIGRATION, MUTATION, and SELECTION
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different
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Do sex chromosomes have an equilibrium SIMILAR or DIFFERENT from Hardy-Weinberg?
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Female: ZW or Z-
Male: ZZ
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In Birds, which of these sex chromosomes are male? Which are femaleZW ZZ Z-
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Sex Limited Inheritance
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phenotypes can only be observed in one sex
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Sex Influenced Inheritance
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heterozygotes express one phenotype in a certain sex and another in the other sex
eg. male pattern baldness: B1B2 = baldness in male, but normal for females
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Imprinted Genes
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genes that are only expressed if they are inherited from one parent or the other
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- Migration
- Selection
- in the very long term -> Mutation
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Things that change allele frequency:
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Variability
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What changes when allele frequencies change?
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Migration
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the movement of alleles from one population to another
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Selection
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the process that determines which individuals become the parents in the next generation
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Natural Selection
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Bottlenecks, evolution, extinction, and environmental factors are examples of what kind of selection?
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Bottleneck
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an incidence that has caused the population to shrink significantly, after this major population drop, the population either adapts and recovers
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Artificial Selection
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humans deciding for plants and animals, and goal oriented reasons (eg. appearance or productivity) are examples of what kind of selection?
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Qualitative Traits
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these traits are controlled by one or a few loci and have discrete phenotypes (eg. eye colour)
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Quantitative Traits
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these traits are controlled by multiple loci and usually have continuous phenotypes (height, weight)
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Polygenic Trait
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another name for a trait controlled by multiple loci
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Variance
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a measure of how much variability there is within a population for a certain trait
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- Genotype
- Environment
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Variability in the phenotype comes from:
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Heritability is high & the parents and progeny have more similar phenotypes
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If a trait has a strong genetic influence from parents, then heritability is:
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Heritability is low & the parents and progeny may differ more
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if a trait has a weak genetic influence from parents, then heritability is:
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Traits that are HIGH
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height, weight, and growth are heritability traits that are

(High/Medium/Low)
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Traits that are MEDIUM
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milk production, some behaviours, and racing speed are heritability traits that are

(High/Medium/Low)
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Traits that are LOW
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health, fitness, and reproduction are heritability traits that are

(High/Medium/Low)
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Behaviour
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a reaction to stimuli, external or internal, that can alter an organism's response to its environment
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The Nervous System
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much of the study of behaviour in genetics focuses on the development, structure, and function of what?
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Geotaxis
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the movement toward or away from gravity
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Microarrays
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these things make it possible to measure changes in hundreds or thousands of genes in a single experiment
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Na/K pump
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The movement of an impulse in the nervous system down a neuron is powered by:
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Huntington's Disease
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inherited as an autosomal dominant disease that affects the development, structure, or function of the brain
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10
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Approximately how many years after onset of does one succumb to Huntington's disease
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Heterozygous
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You would expect a person with an autosomal dominant disease to be:
(Heterozygous/Homozygous)
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Schizophrenia
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There is a large impact of pleiotropy and epigenetic effects on this disease
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They are affected by 100s of genes
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Are autism and schizophrenia affected by one major gene? or 100s of genes
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Schizophrenia
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When one sees deletions in copy number variations the person with a disease (either autism or schizophrenia) is more likely to have:
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Autism
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When one sees duplications in copy number variations the person with a disease (either autism or schizophrenia) is more likely to have:
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Population
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a group of individuals with a common set of genes that lives in the same geographic area and actively, or potentially interbreeds
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Heterozygosity
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Most populations contain an increased degree of (heterozygosity/homozygosity)
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Domestication
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The removal of undesirable traits and breeding for desired ones
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mutation and genetic drift
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some major genetic variation is expected simply as a result of
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Natural Selection
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ants and bees having specific tasks in their colonies for who can carry each of the tasks accordingly
this is an example of
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- Directional
- Stabilizing
- Disruptive
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the three different types of selection for complex traits are:
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Directional Selection
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in this type of selection, phenotypes at one of the spectrum get selected for or against, usually as a result of changes in the environment
eg. beak size in finches increased during dry years
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Stabilizing Selection
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in this type of selection, intermediate types are favoured and both extreme phenotypes are selected against
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Disruptive Selection
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in this type of selection, both phenotypic extremes are selected for, and the intermediates are selected against
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TRUE
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mutation is the only process that creates new alleles in a gene pool
TRUE or FALSE
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FALSE
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mutation by itself plays a highly significant role in changing allele frequencies
TRUE of FALSE
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Genetic Drift
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This occurs when the number of reproducing individuals in a population is too small to ensure that all the alleles in the gene pool will be passed to the next generation in their existing frequencies
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TRUE
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A large population consists of 100 or more individuals
TRUE or FALSE
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Founder Effect (a type of Genetic Drift)
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This occurs when a population originates from a small number of individuals whose gene pool may not reflect that of the larger population from which the founders are drawn
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TRUE
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Genetic drift can arise from population bottleneck
TRUE or FALSE
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FALSE
it only changes the genotype frequency
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Non-random mating changes genotype frequency and allele frequency
TRUE or FALSE
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Positive Assortive Mating (form of non-random mating)
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similar genotypes are most likely to mate than dissimilar ones
eg. Humans tend to be attracted to others who look like themselves
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Negative Assortive Mating (form of non-random mating)
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dissimilar genotypes are more likely to mate than similar ones
eg. a cow with bad feet and legs will be mated to a bull with good feet and legs
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Inbreeding
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mating among closely related individuals
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Inbreeding
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this increases the proportion of homozygotes in a population
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Species
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A group of actually or potentially interbreeding organisms that is reproductively isolated in nature from all other such groups
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Speciation
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the formation of a new species
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Reproductive Isolating Mechanisms
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the biological barriers that prevent or reduce interbreeding between populations
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- Prezygotic Isolating Mechanisms
- Postzygotic Isolating Mechanisms
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What are the two types of reproductive isolating mechanisms
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Prezygotic Isolating Mechanisms
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This reproductive isolating mechanism prevents mating from taking place, gametes most likely won't ever meet
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Postzygotic Isolating Mechanisms
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This reproductive isolating mechanism creates a non viable zygote, either resulting in weakness, sterility, or both
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Phylogeny
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the evolutionary history of a species
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TRUE
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Neanderthals and modern humans coexisted
TRUE or FALSE
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FALSE
we have a common ancestor but Neanderthals were a separate hominid line
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Neanderthals are of the same hominid as modern humans
TRUE or FALSE
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- Deliberate hunting and harvesting
- Habitat destruction
- Accidental or deliberate introduction of invasive species
- Climate change
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Humans are accelerating the rate of species extinction, directly or indirectly due to:
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Conservation Genetics
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looks to maintaining and restoring population viability
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- Interspecific diversity
- Intraspecific diversity
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Genetic biodiversity can be split into two levels:
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Interspecific diversity
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the number of different species, this varies in diverse ecosystems
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Intraspecific Diversity
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the diversity within a species
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- Intrapopulation diversity
- Interpopulation diversity
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the two types of intraspecific diversity are:
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Intrapopulation diversity
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genetic variation occuring in individuals within a single population
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Interpopulation diversity
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variation occurring between different populations of the same species
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Naturally Rare species
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species that are naturally small in numbers, especially those who survive in unusual habitats
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Newly Rare species
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species whose numbers decline due to some sort of pressure
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- Genetic Drift
- Inbreeding
- Gene Flow
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Small population (<100) can quickly become vulnerable to factors that increase the risk of extinction, these factors include:
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Gene Flow
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this occurs by dispersal of gametes or by migration and is an important mechanism for introducing new alleles to a gene pool and increasing genetic variation
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Migration
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What is the main route for gene flow in animals?
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Cross-pollination and seed dispersal
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How does gene flow occur in plants?
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