MBG 2400 Study Cards – Flashcards
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polymorphism |
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the occurrence of something in different forms among the members of a population or colony, or in the life cycle of an individual organism |
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- Pleiotropy - Epistasis - Linkage |
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Factors affecting independence and F2 ratios |
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Pleiotropy |
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one locus affects more than one trait eg White cat= WW or Ww W allele also causes deafness |
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Epistasis |
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alleles at one locus affect the expression of alleles at a different locus eg. coat colour in labs |
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linkage |
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two or more loci are on the same chromosome |
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Hardy-Weinberg Equilibrium |
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seen in a LARGE, RANDOM MATING population in the ABSENCE of MIGRATION, MUTATION, and SELECTION |
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different |
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Do sex chromosomes have an equilibrium SIMILAR or DIFFERENT from Hardy-Weinberg? |
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Female: ZW or Z- Male: ZZ |
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In Birds, which of these sex chromosomes are male? Which are femaleZW ZZ Z- |
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Sex Limited Inheritance |
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phenotypes can only be observed in one sex |
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Sex Influenced Inheritance |
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heterozygotes express one phenotype in a certain sex and another in the other sex eg. male pattern baldness: B1B2 = baldness in male, but normal for females |
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Imprinted Genes |
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genes that are only expressed if they are inherited from one parent or the other |
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- Migration - Selection - in the very long term -> Mutation |
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Things that change allele frequency: |
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Variability |
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What changes when allele frequencies change? |
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Migration |
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the movement of alleles from one population to another |
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Selection |
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the process that determines which individuals become the parents in the next generation |
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Natural Selection |
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Bottlenecks, evolution, extinction, and environmental factors are examples of what kind of selection? |
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Bottleneck |
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an incidence that has caused the population to shrink significantly, after this major population drop, the population either adapts and recovers |
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Artificial Selection |
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humans deciding for plants and animals, and goal oriented reasons (eg. appearance or productivity) are examples of what kind of selection? |
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Qualitative Traits |
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these traits are controlled by one or a few loci and have discrete phenotypes (eg. eye colour) |
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Quantitative Traits |
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these traits are controlled by multiple loci and usually have continuous phenotypes (height, weight) |
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Polygenic Trait |
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another name for a trait controlled by multiple loci |
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Variance |
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a measure of how much variability there is within a population for a certain trait |
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- Genotype - Environment |
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Variability in the phenotype comes from: |
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Heritability is high & the parents and progeny have more similar phenotypes |
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If a trait has a strong genetic influence from parents, then heritability is: |
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Heritability is low & the parents and progeny may differ more |
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if a trait has a weak genetic influence from parents, then heritability is: |
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Traits that are HIGH |
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height, weight, and growth are heritability traits that are (High/Medium/Low) |
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Traits that are MEDIUM |
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milk production, some behaviours, and racing speed are heritability traits that are (High/Medium/Low) |
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Traits that are LOW |
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health, fitness, and reproduction are heritability traits that are (High/Medium/Low) |
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Behaviour |
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a reaction to stimuli, external or internal, that can alter an organism's response to its environment |
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The Nervous System |
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much of the study of behaviour in genetics focuses on the development, structure, and function of what? |
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Geotaxis |
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the movement toward or away from gravity |
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Microarrays |
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these things make it possible to measure changes in hundreds or thousands of genes in a single experiment |
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Na/K pump |
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The movement of an impulse in the nervous system down a neuron is powered by: |
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Huntington's Disease |
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inherited as an autosomal dominant disease that affects the development, structure, or function of the brain |
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10 |
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Approximately how many years after onset of does one succumb to Huntington's disease |
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Heterozygous |
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You would expect a person with an autosomal dominant disease to be: (Heterozygous/Homozygous) |
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Schizophrenia |
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There is a large impact of pleiotropy and epigenetic effects on this disease |
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They are affected by 100s of genes |
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Are autism and schizophrenia affected by one major gene? or 100s of genes |
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Schizophrenia |
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When one sees deletions in copy number variations the person with a disease (either autism or schizophrenia) is more likely to have: |
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Autism |
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When one sees duplications in copy number variations the person with a disease (either autism or schizophrenia) is more likely to have: |
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Population |
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a group of individuals with a common set of genes that lives in the same geographic area and actively, or potentially interbreeds |
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Heterozygosity |
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Most populations contain an increased degree of (heterozygosity/homozygosity) |
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Domestication |
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The removal of undesirable traits and breeding for desired ones |
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mutation and genetic drift |
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some major genetic variation is expected simply as a result of |
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Natural Selection |
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ants and bees having specific tasks in their colonies for who can carry each of the tasks accordingly this is an example of |
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- Directional - Stabilizing - Disruptive |
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the three different types of selection for complex traits are: |
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Directional Selection |
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in this type of selection, phenotypes at one of the spectrum get selected for or against, usually as a result of changes in the environment eg. beak size in finches increased during dry years |
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Stabilizing Selection |
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in this type of selection, intermediate types are favoured and both extreme phenotypes are selected against |
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Disruptive Selection |
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in this type of selection, both phenotypic extremes are selected for, and the intermediates are selected against |
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TRUE |
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mutation is the only process that creates new alleles in a gene pool TRUE or FALSE |
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FALSE |
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mutation by itself plays a highly significant role in changing allele frequencies TRUE of FALSE |
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Genetic Drift |
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This occurs when the number of reproducing individuals in a population is too small to ensure that all the alleles in the gene pool will be passed to the next generation in their existing frequencies |
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TRUE |
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A large population consists of 100 or more individuals TRUE or FALSE |
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Founder Effect (a type of Genetic Drift) |
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This occurs when a population originates from a small number of individuals whose gene pool may not reflect that of the larger population from which the founders are drawn |
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TRUE |
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Genetic drift can arise from population bottleneck TRUE or FALSE |
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FALSE it only changes the genotype frequency |
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Non-random mating changes genotype frequency and allele frequency TRUE or FALSE |
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Positive Assortive Mating (form of non-random mating) |
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similar genotypes are most likely to mate than dissimilar ones eg. Humans tend to be attracted to others who look like themselves |
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Negative Assortive Mating (form of non-random mating) |
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dissimilar genotypes are more likely to mate than similar ones eg. a cow with bad feet and legs will be mated to a bull with good feet and legs |
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Inbreeding |
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mating among closely related individuals |
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Inbreeding |
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this increases the proportion of homozygotes in a population |
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Species |
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A group of actually or potentially interbreeding organisms that is reproductively isolated in nature from all other such groups |
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Speciation |
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the formation of a new species |
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Reproductive Isolating Mechanisms |
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the biological barriers that prevent or reduce interbreeding between populations |
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- Prezygotic Isolating Mechanisms - Postzygotic Isolating Mechanisms |
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What are the two types of reproductive isolating mechanisms |
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Prezygotic Isolating Mechanisms |
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This reproductive isolating mechanism prevents mating from taking place, gametes most likely won't ever meet |
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Postzygotic Isolating Mechanisms |
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This reproductive isolating mechanism creates a non viable zygote, either resulting in weakness, sterility, or both |
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Phylogeny |
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the evolutionary history of a species |
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TRUE |
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Neanderthals and modern humans coexisted TRUE or FALSE |
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FALSE we have a common ancestor but Neanderthals were a separate hominid line |
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Neanderthals are of the same hominid as modern humans TRUE or FALSE |
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- Deliberate hunting and harvesting - Habitat destruction - Accidental or deliberate introduction of invasive species - Climate change |
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Humans are accelerating the rate of species extinction, directly or indirectly due to: |
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Conservation Genetics |
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looks to maintaining and restoring population viability |
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- Interspecific diversity - Intraspecific diversity |
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Genetic biodiversity can be split into two levels: |
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Interspecific diversity |
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the number of different species, this varies in diverse ecosystems |
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Intraspecific Diversity |
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the diversity within a species |
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- Intrapopulation diversity - Interpopulation diversity |
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the two types of intraspecific diversity are: |
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Intrapopulation diversity |
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genetic variation occuring in individuals within a single population |
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Interpopulation diversity |
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variation occurring between different populations of the same species |
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Naturally Rare species |
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species that are naturally small in numbers, especially those who survive in unusual habitats |
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Newly Rare species |
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species whose numbers decline due to some sort of pressure |
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- Genetic Drift - Inbreeding - Gene Flow |
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Small population (<100) can quickly become vulnerable to factors that increase the risk of extinction, these factors include: |
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Gene Flow |
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this occurs by dispersal of gametes or by migration and is an important mechanism for introducing new alleles to a gene pool and increasing genetic variation |
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Migration |
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What is the main route for gene flow in animals? |
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Cross-pollination and seed dispersal |
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How does gene flow occur in plants? |