Home Page Flashcards Itopride hydrochloride C20H27ClN2O4 structure - Flashcards

Itopride hydrochloride C20H27ClN2O4 structure – Flashcards

Flashcard maker : Sabrina Peterson

Contents

Experimental Melting Point:
Experimental Flash Point:
Experimental Gravity:
Experimental Solubility:
Safety:
Target Organs:
Bio Activity:

Molecular Formula	C₂₀H₂₇ClN₂O₄
Average mass	394.892 Da
Density
Boiling Point
Flash Point
Molar Refractivity
Polarizability
Surface Tension
Molar Volume

Experimental data
Predicted – ACD/Labs
Predicted – ChemAxon

Experimental Physico-chemical Properties
- Experimental Melting Point:
  
  191 °C LKT Labs
  [I7757]
  
  194 °C Biosynth Q-201260
  
  194-1950 °C LabNetwork LN01303528
- Experimental Flash Point:
  
  262.3 °C Biosynth Q-201260
- Experimental Gravity:
  
  262.3 g/mL Biosynth Q-201260
- Experimental Solubility:
  
  DMSO:52mg/mL MedChem Express HY-B0732
  
  Soluble in water or methanol. Sparingly soluble in acetic acid. LKT Labs
  [I7757]

Miscellaneous

Safety:

P261; P262 Biosynth Q-201260
Target Organs:

AChR antagonist;Dopamine Receptor antagonist TargetMol T1552

Bio Activity:

AChE MedChem Express HY-B0732

Itopride hydrochloride is an AChE inhibitor (acetylcholinesterase) and D2DR inhibitor. MedChem Express

Itopride hydrochloride is an AChE inhibitor (acetylcholinesterase) and D2DR inhibitor.; Target: AChE; Itopride is a gastroprokinetic benzamide derivative. MedChem Express HY-B0732

Itopride hydrochloride is an AChE inhibitor (acetylcholinesterase) and D2DR inhibitor.;Target: AChE;Itopride is a gastroprokinetic benzamide derivative. The IC50 of itopride with AChE (2.04 +/- 0.27 microM) was, however, 100-fold less than that with BuChE, whereas in the case of neostigmine with AChE (11.3 +/- 3.4 nM), it was 10-fold less. The inhibitory effect of itopride on cholinesterase (ChE) activity in guinea pig gastrointestine was much weaker than that on pure AChE. the IC50s of itopride against ChE activities were found to be about 0.5 microM. The IC50 of itopride for electric eel and guinea pig gastrointestinal AChE inhibition was 200 times and 50 times as large as that of neostigmine, respectively [1]. MedChem Express HY-B0732

Musciarinic AChR;Dopamine receptor TargetMol T1552

Neuronal Signaling MedChem Express HY-B0732

Neuronal Signaling; MedChem Express HY-B0732

Neuroscience TargetMol T1552

Predicted data is generated using the ACD/Labs Percepta Platform – PhysChem Module

No predicted properties have been calculated for this compound.

Density:
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction:
Molar Refractivity:
#H bond acceptors:
#H bond donors:
#Freely Rotating Bonds:
#Rule of 5 Violations:

ACD/LogP:
ACD/LogD (pH 5.5):
ACD/BCF (pH 5.5):
ACD/KOC (pH 5.5):
ACD/LogD (pH 7.4):
ACD/BCF (pH 7.4):
ACD/KOC (pH 7.4):
Polar Surface Area:
Polarizability:
Surface Tension:
Molar Volume:

Click to predict properties on the Chemicalize site

Itopride hydrochloride C20H27ClN2O4 structure – Flashcards

Experimental Melting Point:

Experimental Flash Point:

Experimental Gravity:

Experimental Solubility:

Safety:

Target Organs:

Bio Activity:

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