Exam 5 Geriatric & Pediatric Laboratory Assessment – Flashcards

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question
According to 2011 data from the CDC what was the leading cause of death in people 65 and older?
answer
Heart Disease
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According to 2011 data from the CDC what was the 2nd leading cause of death in people 65 and older?
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Cancer
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What "normal" changes are observed as you get older?
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-Decline in total body water (dehydration) and muscle mass
-Increased lipids and adipose tissue
-Decline in lung, heart, liver, kidney, GI, immune and endocrine functions
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As Renal Function Decreases, what happens to the risk of toxicity?
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Increases
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As Renal Function is reduced by half with patients who are 65 or older, what happens to GFR, CrCl, drug clearance?
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Decrease; risk of toxicity
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What parts of the Lipids are increased with patients who are 65 or older?
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Cholesterol & Tg
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As Cholesterol & Tg increase in patients who are 65 years or older, what does this raise the risk of?
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Atherosclerosis & CHD
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What Liver Function parts decrease as you become older?
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Albumin and protein
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As Renal Function is reduced by half with patients who are 65 or older, what happens to Plasma BUN, Cr and uric acid?
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Increase
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With Liver Function what is the result of Drug detoxification as you get older?
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Drugs/alcohol become more toxic
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With Liver Function, what happens to AST, ALT, ALP, GGT, LD as you get older?
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Increase
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As you get older what happens to pO2?
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Decreases
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As you get older what happens to pCO2?
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Increases
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As pCO2 increases as you get older you become more susceptible to what?
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Respiratory acidosis
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True or False:
Both Hyper- and hypothyroidism are common for patients who are 65 or older
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True
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What happens to the following Endocrine Function as you get older:
Testosterone
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Decreases (andropause)
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What happens to the following Endocrine Function as you get older:
Estrogen
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Decreases (menopause)
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What happens to the following Endocrine Function as you get older:
GH
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Decreases
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What happens to the following Endocrine Function as you get older:
Hypothalamus
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Shrinks, causing dehydration among other things
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For patients who are 65 and older, what does a decrease in Estrogen increase the risk of?
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Osteoporosis/CHD
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What happens to your Glucose Tolerance as you get older?
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Declines
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What happens to the Prevalance of Type 2 Diabetes as you get older?
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Increases
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When combined with high lipids, as you age, the risk of _____ increases x 20
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AMI
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True or False:
Of the 28 conditions that the Arkansas newborn screening tests none can be cured
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True
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True or False:
Of the 28 conditions that the Arkansas newborn screening tests none can be cured, but many can be controlled
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True
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Match the following information to the disease:
Decreased T4 & Increased TSH
Cretinism
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Congenital Hypothyroidism
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Match the following information to the disease:
Children 3 & under get a clinitest
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Galactosemia
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Match the following information to the disease:
Phenylalanine Defect
Guthrie Bacterial Inhibition
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PKU (phenylketonuria)
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Match the following information to the disease:
Elevated levels of immunoreactive trypsinogen
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Cystic fibrosis
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What is immunoreactive trypsinogen (IRT)?
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Enzyme secreted by the pancreas
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If the IRT is Positive, you should follow up with what?
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Genetic testing and sweat chloride
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What do Birth trauma and RDS lead to?
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respiratory acidosis and tissue hypoxia
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As Lactate Increases what happens to pCO2?
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Increases
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As Lactate Increases what happens to pO2?
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Decreases
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What is the leading cause of death in preemies?
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RDS
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What is used as a predictor for pre-term delivery?
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Fetal Fibronectin
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What is used to assess the source of jaundice in neonatal/pediatric patients?
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Bilirubin
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Physiologic jaundice of the newborn - bilirubin levels should fall to adult levels by ____ ____
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1 month
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What is the Rx for Physiologic jaundice of the newborn?
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Phototherapy
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HDN (pathologic jaundice) is caused by what?
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Overproduction of bilirubin from excess RBC lysis
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HDN is Mostly what kind of bilirubin
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Unconjugated
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With HDN, there is a risk of what after birth?
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Kernicterus
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What type of charts or tests would you perform to determine bilirubin levels in neonatal patients?
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OD 450 / Liley Graph
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With Gestational Diabetes, what is there a risk of?
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Insulin shock, RDS and macrosomia
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True or False:
Glucose levels in the newborn should be similar to adult levels
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True
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What is the most prevalent type of diabetes in the pediatric population?
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Type 1
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What is the most prevalent type of diabetes in the geriatric population?
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Type 2
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Infantile diarrhea interferes with what elements absorption?
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Calcium
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Infantile diarrhea interfering with Calcium absorption is consistent with what condition?
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Neonatal tetany
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What element is always measured in cases of seizure of unknown origin?
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Calcium
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What are the 2 Preanalytical concerns with pediatric patients?
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Instruments may not accept pediatric collection tubes
Evaporation
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Neonatal/Pediatric:
Ammonia is tied to what condition?
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Reye's Syndrome
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Neonatal/Pediatric:
Ammonia can lead to what?
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Liver disease and encephalopathy
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Neonatal/Pediatric- Ammonia is tied to which of the following:
Metabolic acidosis
Metabolic alkalosis
Respiratory acidosis
Respiratory alkalosis
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Metabolic alkalosis
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With the neonatal/pediatric population is Ammonia levels are not diagnosed in a timely manner than what can occur?
answer
High Mortality
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