Exam 4 Chemistry Review/Study Questions Part 4

question

What is the formula for the % Tf Saturation?
answer

(Total Iron / TIBC ) x 100
question

True or False:
Ferritin levels in serum will decrease BEFORE total iron content is depressed
answer

True
question

What does Total Serum Iron Measure?
answer

Iron bound to Tf
question

What is Transferrin often measured by?
answer

Nephelometry
question

What is Total Iron Binding Capacity a measure of?
answer

Capacity of transferrin to bind more iron
question

Usually Tf is what percent saturated with iron?
answer

20-50%
question

What is the formula to calculate TIBC knowing Tf?
answer

TIBC = Tf x 1.25
question

True or False:
You can not calculate TIBC if Tf<70
answer

True
question

True or False:
You can not calculate % Tf Saturation is TIBC<5
answer

True
question

Name the condition associated with the following:
Iron – Decreased
Ferritin – Decreased
Transferrin – Increased
RBC Count – Decreased
H&H – Decreased
MCHC – Decreased
Micro/Hypo
answer

IDA
question

Name the condition associated with the following:
Iron – Increased
Ferritin – Increased
Transferrin – Decreased
Hemochromatosis
answer

Iron Overload
question

Name the condition associated with the following:
Iron – Decreased
Ferritin – Normal to Increased
Transferrin – Decreased
answer

Anemia of Chronic Disease
question

What is the term used to describe hereditary iron overload disease?
answer

Hemochromatosis
question

What can you use to treat Iron Overload?
answer

Therapeutic phlebotomy or chelators
question

Which iron disorder is connected to the following:
Cancer
Hogkins
SLE
Renal failure with decreased erythropoietin
answer

Anemia of Chronic Disease
question

Given the following Determine the Iron Disease State:
Total Fe – Decreased
Ferritin – Decreased
Transferrin – Increased
TIBC – Increased
% Saturation – Decreased
answer

IDA
question

Given the following Determine the Iron Disease State:
Total Fe – Increased
Ferritin – Increased
Transferrin – Decreased
TIBC – Decreased
% Saturation – Increased
answer

Hemochromatosis
question

Given the following Determine the Iron Disease State:
Total Fe – Decreased
Ferritin – Normal to Increased
Transferrin – Decreased
TIBC – Decreased
% Saturation – Decreased
answer

Anemia of Chronic Disease
question

Match the trace element with the deficiency results:
o Hypochromic anemia
o Bone malformation
o Menke’s syndrome
o Wilson’s disease
answer

Copper
question

Match the trace element with the deficiency results:
o Impaired immunity and wound healing
o Impotence
o Growth retardation
oSensory alterations
answer

Zinc
question

Match the trace element with the deficiency results:
o Megaloblastic anemia
answer

Cobalt
question

Match the trace element with the deficiency results:
o Reduced glucose tolerance
answer

Chromium
question

Match the trace element with the deficiency results:
o Bone defects and stunted growth
o Clotting disorders
o Epilepsy
answer

Manganese
question

Match the trace element with its Functions:
Erythropoiesis
Cellular respiration
Skeletal development
Nucleic acid/protein synthesis
Collagen formatio
answer

Copper
question

Match the trace element with its Functions:
Enzyme structure
RNA/DNA synthesis
Sensory development
Growth
Wound healing
Immune response
answer

Zinc
question

Match the trace element with its Functions:
Constituent of Vit B12
Needed for folate metabolism
answer

Cobalt
question

Match the trace element with its Functions:
“Glucose Tolerance Factor”,
increases effects of insulin
answer

Chromium
question

Match the trace element with its Functions:
Enzyme activator
Reproductive function
Bone and tissue formation
answer

Manganese
question

What is the formula of the Henderson-Hasselbalch Equation?
answer

pH = pK’ + log (Buffer/Acid)
question

Define the following:
Acid
answer

Yield hydrogen ions (H+) when dissolved in H2O
Primary sources in the blood:H+, H2CO3 (carbonic acid) and pCO2
question

Define the following:
Base
answer

Yield hydroxyl ions (OH-)
Primary source in the blood: HCO3 (bicarbonate)
question

Define the following:
Buffer
answer

A system consisting of a weak acid and
a weak base that resists pH changes
question

Great quantities of H+ come from where?
answer

Cell metabolism and food digestion
question

Define the following:
Total CO2
answer

The sum of the various CO2-containing substances in plasma
question

Acidemia/acidosis = arterial pH below
answer

7.35
question

Alkalemia/alkalosis = arterial pH above
answer

7.45
question

What are the various CO2-containing substances in plasma?
answer

Dissolved CO2 gas from cellular respiration (pCO2)
Carbonic acid (H2CO3)
Bicarbonate ion (HCO3-)
question

Total CO2 = ______ mmol/L
answer

23-29
question

HCO3 = ________mmol/L
answer

22-26
question

True or False:
Bicarbonate-Carbonic Acid System is the principle buffering system
answer

True
question

Normally, the ratio of HCO3 to CO2 is _____
answer

20:1
question

A fall in the ratio of HCO3 to CO2 results in what?
answer

Acidosis
question

A rise in the ratio of HCO3 to CO2 results in what?
answer

Alkalosis
question

What 2 organs will respond to restore the 20:1 HCO3 to CO2 ratio?
answer

Lungs and/or Kidneys
question

True or False:
If plasma becomes acidic, HCO3 can diffuse out of the RBC to buffer the blood
answer

True
question

As HCO3 diffuses out of the RBC to buffer the blood, what moves in?
answer

Chloride
question

____ventilation: More CO2 is lost and blood becomes alkaline
answer

Hyperventillation
question

____ventilation: CO2 accumulates and blood becomes acidic
answer

Hypoventilation
question

True or False:
The response time to ventilation changes occurs within seconds
answer

True
question

True or False:
Tubules will excrete or retain acid (H+) or alkaline (HCO3)
answer

True
question

When H+ is retained by the kidneys, what is excreted?
answer

Na+
question

When Na+ is retained by the kidneys, what is excreted?
answer

H+
question

As H+ is excreted or Retained by the kidneys, what moves with it?
answer

K+
question

Correction of pH may take how much time when regulated by the kidneys?
answer

2-4 days
question

What is it called when:
pH has returned to normal, other 2 parameters are abnormal
answer

Fully Compensated
question

What is it called when:
the pH and 1 other parameter are abnormal
answer

Uncompensated
question

What is it called when:
All 3 parameters are abnormal
answer

Partially Compensated

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