Chapter 18 Cards Answers – Flashcards
Flashcard maker : Aiden Boyd
The compound CH3CH2NHCH3 is classified as a
Secondary amine
The compound CH3CH2NH2 is classified as a
Primary amine
Which of the following compounds is an amine?
(CH3CH2)2NH
HNCH3-benzene ring-Br
N-methyl-3-bromoaniline
Aminobenzene is properly known as
Aniline
What is the name of this compound?
CH3-NCH2CH3-CH3
CH3-NCH2CH3-CH3
Ethyldimethylamine
Name the following compound CH3-NH-CH3
Dimethyl amine
Amines contain the element
Nitrogen
In what kind of amine is the nitrogen directly bonded to two carbon atoms?
Secondary
When naming amines according to the IUPAC system, the -e in the corresponding alkane is replaced with
-amine
Aniline is a(n)
Primary aromatic amine
What prefix is used to show that a small alkyl group is attached to the nitrogen of aniline and not to the aromatic ring?
N-
How many alkyl substituents does N-ethyl-N-methylaniline have?
Two
Which of the following compounds CANNOT form hydrogen bonds with water?
CH3CH2CH3
Which of the following compounds CANNOT form hydrogen bonds with water?
(CH3CH2)3N
Which of the following represents the complete neutralization of N,N-dimethylamine?
CH3NH-CH3 + HCl -> CH3NH2+-CH3 + Cl-
When ethylamine dissolves in water, a solution of ____ is produced.
Ethylammonium hydroxide
Diethylamine and HCl react to produce
Diethylammonium chloride
What relation does the boiling point of an amine have to a similar hydrocarbon?
Higher
Amines can form ____ bonds with other molecules.
Hydrogen
What kind of amine can NOT form hydrogen bonds?
Tertiary
Amines are
Bronsted-Lowry bases
The odor of an amine can be neutralized with
Acids
Choline is a quaternary ammonium compound with a ___ charge on the nitrogen.
Positive
In what form are amine-containing drugs often administered?
Amine salt
What kind of pharmacologic activity is found in the amines Procaine and Lidocaine?
Local anesthetic
What are alkaloids?
Physiologically active nitrogen compounds derived from plants
Identify the heterocyclic amine in the choices below.
Pyrrolidine
Among the choices below, identify the heterocyclic amine found in DNA.
Purine
Nicotine, coniine, quinine, atropine,
and morphine are all examples of
and morphine are all examples of
Alkaloids
Procaine and Lidocaine were developed by modifying the structure of
Cocaine
Physiologically active nitrogen-containing compounds produced by plants are called
Alkaloids
Which of the following is NOT an alkaloid?
Diethylamine
What functional group is always found in alkaloids (such as caffeine, nicotine, and digitalis)?
Amine
Cyclic compounds that contain a nitrogen atom are called
Heterocyclic Compounds
What is the major functional group in the following compound?
O=CH3CNHCH3
O=CH3CNHCH3
Amide
What is the name of this compound?
O=CNHCH2CH3-Hexagon shape
O=CNHCH2CH3-Hexagon shape
N-ethylbenzamide
One name for this compound is O=CH3CH2-C-NH-CH2CH3
N-ethylpropanamide
Which chemical class does phenobarbital belong to?
Amide
What kind of compound is urea?
Amide
What is the chemical classification of the barbiturate sedatives?
Cyclic amides
Amines having fewer than ___ carbons are generally water soluble.
Six
Aniline is the IUPAC approved name for aminobenzene. T or F.
True
Aniline is a primary amine. T or F.
True
Ethylmethylamine is a tertiary amine. T or F.
False
The amine functional group is rarely found in pharmacologically active compounds. T or F.
False
Primary amines contain two carbon-containing groups bonded to the nitrogen atom. T or F.
False
Amines do not form hydrogen bonds. T or F.
False
Amines do not ionize in water. T or F.
False
Amines act as weak acids by accepting protons from water. T or F.
False
Amine salts are odorless and usually highly water soluble. T or F.
True
Quinine is an alkaloid used for treatment of malaria. T or F.
True
Heterocyclic amines contain a nitrogen atom in a ring. T or F.
True
Aspirin substitutes may contain amide rather than ester functional groups. T or F.
True
Amides are bases. T or F.
False
The compound CH3CH2NHCH3 is an
Amine
When acetic acid reacts with ammonia, NH3, the reaction is called amidation yields
Acetamide
What is the major functional group in the following compound?
O=CH3CNHCH3
O=CH3CNHCH3
Amide
In the formation of N-ethylacetamide, the reactants are
Acetic acid and ethylamine
The amide formed in the reaction of benzoic acid and ethylamine is
O=CNHCH2CH3-Benzene Ring
What is the name of this compound?
O=CNHCH2CH3-Benzene Ring
O=CNHCH2CH3-Benzene Ring
N-ethylbenzamide
One name for this compound is
O=CH3CH2CNHCH2CH3
O=CH3CH2CNHCH2CH3
N-ethylpropanamide
The reaction of butanoic acid and dimethylamine gives
N,N-dimethylbutanamide
Amides are derivatives of ___ and ___.
Amines and carboxylic acids
Which of the following is the reaction for the acid hydrolysis of N-methylacetamide?
O
O
||
||
CH3CNHCH3+H2O+HCl->CH3COH+CH3NH3+Cl-
O
||
||
CH3CNHCH3+H2O+HCl->CH3COH+CH3NH3+Cl-
Which of the following is the reaction for the base hydrolysis of N-ethylformamide?
O
O
||
||
HCNHCH2CH3+NaOH->HCO-Na+ + CH3CH2-NH2
O
||
||
HCNHCH2CH3+NaOH->HCO-Na+ + CH3CH2-NH2
The compound O=CH3CH2CNHCH3 is an
Amide
The correct name for O=HCNHCH2CH3 is
N-ethyl formamide
With the correct choice of acid, acid hydrolysis of acetamide could produce
Acetic acid and ammonium chloride
With the correct choice of acid, the product of the acid hydrolysis of N-methylbenzamide could be
Benzoic acid and methylammonium chloride
What pharmacologically active amine is responsible for the signs and symptoms encountered in an allergic reaction?
Histamine
Which of the following is not a neurotransmitter?
Pyridine
A neurotransmitter
Transmits a nerve impulse
In response to allergic reactions or injury to cells, the body increases the production of
Histamine
