Ch 2, 3, 4, – Flashcards

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question
Choose the correct proportion of water to body weight to be expected in a healthy male adult's body: 30% 45% 60% 70%
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60%
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Choose the correct proportion of blood (to body weight) in an adult male's body: 30% 20% 10% 4%
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4%
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Insensible fluid loss refers to water lost through? perspiration only feces only perspiration and expiration urine and feces
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perspiration and expiration
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When the osmotic pressure of the blood is elevated above normal, water would shift from the: blood into the cells interstitial compartment into the cells interstitial compartment into the blood cells into the interstitial compartment
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interstitial compartment into the blood.
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Which of the following would result from a deficit of plasma proteins? increased osmotic pressure decreased osmotic pressure increased hydrostatic pressure decreased hydrostatic pressure
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decreased osmotic pressure
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Which of the following would cause edema? decreased capillary hydrostatic pressure increased capillary osmotic pressure decraesed capillary permeability increased capillary permeability
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increased capillary permeability
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Which of the following would likely be related to an elevated hematocrit reading? fluid excess fluid deficit increased sodium level decreased erythrocytes
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fluid deficit
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Which of the following is a typical sign of dehydration? Rapid, strong pulse low hematocrit increased urine output rough oral mucosa
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rough oral mucosa
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Which of the following is the primary cation in the extracellular fluid? Sodium Potassium Calcium Iron
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Sodium
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Which of the following is a common cause of hyponatremia? Loss of the thirst mechanism Excessive sweating Excessive aldosterone secretion Prolonged period of rapid, deep respirations
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Excessive sweating
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Which of the following is a common effect of both hypokalemia and hyperkalemia? skeletal muscle twitch and cramps oliguria elavated serum pH cardiac arrythmias
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cardiac arrythmias
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Choose the correct effect of increased parathyroid hormone? increased movement of calcium ions into the bones increased activation of vitamin D increased absorption of calcium from the digestive tract decreased reaborption of calcium in the kidneys
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increased absorption of calcium from the digestive tract
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Which of the following results from hypocalcemia? Low serum phosphate levels nausea and constipation skeletal muscle twitch and spasms weak cardiac contractions
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skeletal muscle twitch and spasms weak cardiac contractions
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Which of the following causes tetany? increased permeability of nerve membranes due to low serum calcium excess calcium ions in skeletal muscle due to excess parathyroid hormone (PTH) excess calium ions inside somatic nerves as a result of neoplasms increased stimulation of the nerves in the cerebral cortex
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increased permeability of nerve membranes due to low serum calcium
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Which of the following is considered normal serum pH? 4.5-8 7.0 7.4 8
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7.4
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When many excess hydrogen ions accumulated in the blood, what happens to serum pH? The pH decreases increases remains constant varies based on metabolism
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decreases
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What is the slowest but most effective control for acid-base balance? respiratory system buffer system in the blood kidneys brain
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kidneys
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Which of the following is essential in order to maintain serum pH within normal range? Carbonic acid and bicarbonate ion must be present in equal quantities all excess carbonic acid must be excreted by the kidneys the concentration of bicarbonate ion must remain constant the ratio-of carbonic acid to bicaronate ion must be 1.20
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the ratio-of carbonic acid to bicaronate ion must be 1.20
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Which is the correct effect on the body of abnormally slow respirations? increased carbonioc acid decreased carbonic acid increased bicarbonate acid decreased bicarbonate acid
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increased carbonioc acid
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Which condition is likely to cause of metabolic acidosis? slow shallow respirations prolonged diarrhea mild vomitting excessive fluid in the body
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prolonged diarrhea
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What would a serum pH of 7.33 in a patient with kidney disease indicate metabolic alkalosis metabolic acidosis respiratory alkalosis respiratory acidosis
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metabolic acidosis
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Which serum value indicates decompensated metabolic acidosis? pH is below normal range pH is above normal range bicarbonate level decreases bicarbonate level increases
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pH is below normal range
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The direct effect of acidosis are manifested primarily in the functioning of the? Digestive system Urinary system Nervous system Respiratory system
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Nervous system
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Compensation mechanisms in the body for dehydration would include? increased antidiuretic hormone (ADH) decreased aldosterone slow, strong heart contraction peripheral vasodilation
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increased antidiuretic hormone (ADH)
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Which acid-base imbalance results from impaired expiration due to emphysema? metabolic acidosis metabolic alkalosis respiratory acidosis respiratory alkalosis
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respiratory acidosis
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An anxiety attack caused by hyperventilation leading to increased PC02 decreased PC02 respiratory acidosis metabolic acidosis
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decreased PC02
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One of the factors involved in the increased need for water in infants proportionally smaller body surface area higher metabolic rate smaller respiratory capacity greater surface area of expose mucous membranes
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higher metabolic rate
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A prolonged state of metabolic acidosis often leads to hypokalemia hyperkalemia hyponatremia hypercalcemia
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hyperkalemia
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Strenuous physical exercise on a hot day is likely to result hypokalemia hypernatremia hyperchloremia hypovolemia
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hypovolemia
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Which of the following is a manifestation of respiratory alkalosis? bradycardia and deep rapid breathing drowsiness and general lethargy increased nervous system irritability decreased urine pH
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increased nervous system irritability
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Prolonged diarrhea results in loss of fluid and bicarbonate ions, leading to metabolic acidosis increased fluid and serum bicarbonate ions, leading to metabolic acidosis loss of chloride ions only, leading to metabolic alkalosis surplus bicarbonate ions, leading to respiratory alkalosis
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loss of fluid and bicarbonate ions, leading to metabolic acidosis
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In the initial stage, vomiting results in metabolic acidosis metabolic alkalosis respiratory alkalosis None of the above
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metabolic alkalosis
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Which two ions most important for acid-base balance in the body Ka+,Na+ Cl- and HCO3- Ca+,Na+ Na+,C1-
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Cl- and HCO3-
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The biocarbonate-carbonic acid buffer system helps maintain serum pH. Balance of carbonic acid and bicarbonate ion levels are controlled by liver and pancreas lungs and kidneys lungs and plasma proteins kidneys and bone marrow
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lungs and kidneys
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Alkalosis increases irritability and spontaneous stimulation of nerves blocking normal nerve conduction increasing the permeability of nerve membranes blocking movement of calcium ions decreasing phosphate ion levels
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increasing the permeability of nerve membranes
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Hypocalcemia causes weak cardiac contractions permeability of nerve membranes increases insufficient calcium ions are available for muscle contraction low phosphate ion levels prevent muscles contraction excessive amounts of calcium are stored in cardiac muscle
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insufficient calcium ions are available for muscle contraction
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Which of the following is the primary control of serum Na+ levels ADH Aldosterone Serum H+ levels Serum K+ levels
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Aldosterone
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The control center for thirst is located in kidneys thalamus medulla hypothalamus
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hypothalamus
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Three mechanisms that control or compensate for serum pH hypothalamus, metabolic changes by the digestive system, lymphatic system filtration buffer pairs in blood, change in kidney excretion rate, change in respiration rate neural feedback, increase heart rate, decrease in calcium intake modification of water intake, increase capillary permeability, decrease in blood colume
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buffer pairs in blood, change in kidney excretion rate, change in respiration rate
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Hypokalemia refers to a condition in which the serum has very low level of this ion Sodium Phosphate Calcium Potassium
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Potassium
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In the blood and extracellular fluids, hypernatremia refers to a deficient sodium level a excess phosphate level an excess sodium level an exessively low phosphate leve
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a excess phosphate level
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Increased milk and/or antacid intake can contribute to development of "milk-alkali syndrome" which can cause Hyponatremia Hyperkalemia Hypercalcemia Hypovolemia
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Hypercalcemia
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Which of the following are considered to be the toxic effects of a drug? Additional, mild, unwanted effects Unusual, unexpected mild effects Serious, possibly life-threatening effects Reduction of the allergic response
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Serious, possibly life-threatening effects
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What is the unique, simple, and official name assigned to a specific drug for worldwide use? Trade name Chemical name Proprietary name Generic name
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Generic name
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Which is the route of administration by which the largest proportion of the drug dose is likely lost before reaching the site of action? Oral Intramuscular Sublingual Intravenous
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Oral
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Ingesting a drug with a large meal may be likely to: immediately increase the blood level of the drug. prevent gastric irritation. ensure that the total dose is absorbed into the blood. cause more rapid excretion of the drug.
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prevent gastric irritation
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What is the reaction called when two drugs interact to produce a result much greater than the sum of individual effects? Antagonism Beneficial Synergism Potentiation
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Synergism
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At which site are most drugs metabolized and prepared for excretion? Liver Kidneys Circulating blood Lymphoid tissue
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Liver
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In traditional Asian medicine, acupoints are usually located: over pain or other sensory receptors. where blood vessels branch. over joints. on designated meridians.
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on designated meridians.
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Traditional drug or surgical therapy is incorporated with nontraditional methods by: chiropractors. naturopaths. homeopaths. osteopaths.
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osteopaths.
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Contraindications printed on the label of a drug identify: those circumstances under which the drug should probably not be used. those typical side effects associated with this drug. the dosage limits associated with the use of the drug. the maximum shelf life of the medication.
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those circumstances under which the drug should probably not be used.
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After they are metabolized, most drugs are excreted through the: lungs. pancreas. kidneys. large intestine.
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kidneys.
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A drug that binds with selected specific cell receptors may: 1. stimulate activity in those cells. 2. inhibit activity in those cells. 3. change specificity and attach to other cells. 4. be disabled by macrophages. a.1, 2 b. 2, 3 c. 3, 4 d. 1, 3, 4
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a.1, 2
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A placebo may be described as a tablet or capsule: a.that does not contain an active drug. b. that contains a small amount of active drug for use in clinical trials. c. that contains a different drug to be used for its psychological effect. d. that contains high amounts of a drug to determine the maximum dose allowed.
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a.that does not contain an active drug.
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The form of therapy that involves assessment of physical function and works to restore any problems and prevent any further dysfunction using methods such as appropriate exercises and ultrasound is referred to as: a. registered massage therapy. b. naturopathy. c. physiotherapy. d. reflexology.
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c. physiotherapy.
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A medical history should include all: 1. legally prescribed drugs. 2. vitamin or mineral supplements. 3. any medication not requiring a prescription (over-the-counter items). 4. herbal treatments. a. 1 only b. 1, 3 c. 1, 2, 4 d. 1, 2, 3, 4
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d. 1, 2, 3, 4
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Antagonistic drugs may be used to: a.increase the effectiveness of selected drugs. b. prolong the action of a drug. c. act as an antidote when necessary. d. speed up the excretion of a drug.
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c. act as an antidote when necessary.
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The full course of a prescribed antimicrobial drug should be completed so as to prevent: a. undesirable side effects. b. development of resistant microbes. c. an allergic response. d. proper metabolism and excretion of drug.
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b. development of resistant microbes.
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The impulses related to acute pain are usually transmitted by: a. nociceptors. b. myelinated A delta fibers. c. unmyelinated C fibers. d. any sensory fiber with a low pain threshold.
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b. myelinated A delta fibers.
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In which structure do pain impulses ascend the spinal cord? a. Reticular formation b. Corticospinal tract c. Spinothalamic tract d. Relevant dermatome
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c. Spinothalamic tract
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According to the gate-control theory, passage of pain impulses may be naturally blocked: a. at the synapse by entry of other sensory impulses. b. by the stress response. c. by administration of morphine directly into the spinal cord. d. by referring the pain to other parts of the body.
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a. at the synapse by entry of other sensory impulses
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What is the term used to describe the degree of pain that is endured before an individual takes action? a. Pain threshold b. Referred pain c. Phantom pain d. Pain tolerance
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d. Pain tolerance
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What is the definition of endorphins? a. Neurotransmitters at the nociceptors b. Transmitters for sensory impulses c. Opiate-like blocking agents in the central nervous system d. Pain-causing chemical mediators
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c. Opiate-like blocking agents in the central nervous system
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Pain perceived in the left arm during the course of a heart attack is an example of: a. referred pain. b. phantom pain. c. chronic pain. d. subjective pain response.
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a. referred pain.
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A headache that is related to changes in cerebral blood flow is classified as a/an ________ headache. a.tension b.sinus c. migraine d. intracranial
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c. migraine
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Which of the following applies to spinal anesthesia? a. It causes analgesia with loss of consciousness. b. The drug is injected into cerebrospinal fluid (CSF) or the epidural space of the spinal cord. c. The drug stimulates release of endorphins in the spinal cord. d. The transmission of pain impulses is blocked in a small area of the body.
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b. The drug is injected into cerebrospinal fluid (CSF) or the epidural space of the spinal cord.
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Which of the following is a characteristic of acute pain but not of chronic pain? a. Depression and debilitation b. A perception of increased generalized pain and discomfort c. Fatigue and lower pain tolerance d. Severe but short term
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d. Severe but short term
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What is the role of nociceptors? They are: a. pain receptors that are stimulated by thermal, chemical, or physical means. b. spinal nerves that conduct impulses from specific areas of the skin. c. responsible for the state of arousal with pain. d. useful in localizing pain to a specific area of the body.
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a. pain receptors that are stimulated by thermal, chemical, or physical means.
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Intractable pain is best defined as: a. pain that is perceived as occurring in an amputated limb. b. severe pain that cannot be controlled by medication. c. pain perceived as coming from a source other than the actual source. d. pain coming from a specific dermatome.
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b. severe pain that cannot be controlled by medication.
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Which of the following statements is TRUE? a. The brain is more aware of pain impulses when the reticular activating system is depressed. b. Acute pain does not cause a reflex response at the spinal cord synapses. c. Young infants typically respond to pain with tachycardia and increased blood pressure. d. Chronic pain is easier to tolerate without negative effects.
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c. Young infants typically respond to pain with tachycardia and increased blood pressure.
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Ibuprofen is classified as an NSAID and is particularly useful in treating: a. severe pain. b. pain caused by inflammation. c. intracranial pain. d. pain in young infants.
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b. pain caused by inflammation.
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Which of the following analgesics acts to reduce pain at the peripheral site? a. Acetaminophen b. Morphine c. Codeine d. Intravenous general anesthesia
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a. Acetaminophen
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Cancer-related pain has been broken down into three basic categories: pain caused by the advance of the disease and resultant damage to the body, pain that is the result of a coexisting disease unrelated to the cancer, and: a. phantom pain as a result of amputation. b. pain associated with the treatment of the disease. c. pain caused by emotional stress and metabolic changes. d. pain associated with damage to the peripheral nerves.
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b. pain associated with the treatment of the disease.
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Pain that is caused by trauma or disease involving the peripheral nerves is referred to as: a. neuropathic pain. b. central pain. c. neurogenic pain. d. referred pain.
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a. neuropathic pain.
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Pain resulting from a profound, sudden loss of blood flow to an organ or tissues in a specific area of the body is referred to as: a. chronic pain. b. central pain. c. cardiovascular pain. d. ischemic pain.
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d. ischemic pain.
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Which of the following is a characteristic of chronic pain? a. It usually initiates a physiological stress response. b. It always involves a strong emotional response such as high anxiety. c. It is more difficult to diagnose and treat than is acute pain. d. It involves tissue damage to a specific organ.
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c. It is more difficult to diagnose and treat than is acute pain.
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A headache that results from pressure on the meninges surrounding the brain is referred to as a/an: a. intracranial headache. b. intrameningeal headache. c. migraine headache. d. cerebral headache.
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a. intracranial headache.
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Neutrophils: a.are phagocytic cells. b. produce histamine. c. produce antibodies. d. are elevated during an allergic response.
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a.are phagocytic cells.
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Which cells are required to process and present antigens from foreign material as the initial step in the immune response? a. Thelper cells b. Macrophages c. Eosinophils d. Monocytes
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b. Macrophages
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Humoral immunity is mediated by: a.natural killer cells. b.T lymphocytes (T cells). c. B lymphocytes (B cells). d. neutrophils.
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c. B lymphocytes (B cells).
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A secondary immune response differs from the primary immune response in that: a. it is more rapid than the primary response and results in higher antibody levels. b. it is slower than the primary response and doesnt change the antibody levels. c. it occurs at the same time as the primary response but results in a decrease in antibodies. d. it only occurs in hyperallergic reactions and results in a decrease of antibodies.
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a. it is more rapid than the primary response and results in higher antibody levels.
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Which type of immunity is provided by a vaccination? a.Active natural b.Active artificial c. Passive natural d. Passive artificial
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b.Active artificial
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When an allergen binds with IgE antibodies on mast cells, resulting in release of chemical mediators, this reaction is called: a. cytotoxic hypersensitivity. b.immune complex hypersensitivity. c. type I hypersensitivity. d. type IV hypersensitivity.
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c. type I hypersensitivity.
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The role of memory cells is to: a.change into an antibody-secreting cell following activation. b. immediately secrete antibodies following the first exposure to antigen. c. recognize the antigen and stimulate the immune response. d. bind complement to the antibody.
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c. recognize the antigen and stimulate the immune response.
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Which statement applies to contact dermatitis? a.It occurs when IgE antibodies on the skin react with the causative substance. b. It may result from ingested foods. c. Urticaria (hives) gradually spread over the body. d. A type IV reaction occurs in affected areas.
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d. A type IV reaction occurs in affected areas.
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Which of the following causes anaphylaxis? a. A severe, systemic allergic reaction b. Type III hypersensitivity c. Cell-mediated hypersensitivity d. Immune complex deposits in many tissues
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a. A severe, systemic allergic reaction
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Following a positive HIV antibodies blood test and ELISA test, what is the test commonly used for confirmation? a. Agglutination b. Double immunodiffusion test c. Western blot test d. Sedimentation rate test
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c. Western blot test
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Incompatible blood transfusions result in: a. hemolysis of erythrocytes. b. a type I immune response. c. deposits in multiple organs. d. immune deficiency.
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a. hemolysis of erythrocytes.
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An autoimmune disease is: a. excessive formation of antibodies following exposure to foreign material. b. an extreme response to normally harmless material in the environment. c. an abnormal response to ingested food and drugs. d. failure of the immune system to distinguish self from nonself.
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d. failure of the immune system to distinguish self from nonself.
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Systemic lupus erythematosus is caused by: a. a chronic allergic condition. b. development of an immune-deficient state. c. a deficiency of T lymphocytes. d. immune complex deposits of antinuclear antibodies.
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d. immune complex deposits of antinuclear antibodies.
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Distinguishing clinical features of systemic lupus erythematosus include: a. inflammation in multiple organs. b. lack of a specific diagnostic blood test. c. acute onset and nonprogressive course. d. typical skin rash on the chest and back.
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a. inflammation in multiple organs.
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Which of the following are the target cells for HIV? a. Helper T lymphocytes (CD4 lymphocytes) b. B lymphocytes c. Natural killer cells d. Macrophages
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a. Helper T lymphocytes (CD4 lymphocytes)
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A diagnosis of HIV positive means that: a. the number of T lymphocytes in the circulating blood is decreased. b. significant opportunistic infection is present in the body. c. the individual has AIDS. d. the virus and its antibodies are present in the blood.
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d. the virus and its antibodies are present in the blood.
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HIV infection impairs: a. humoral immunity. b. cell-mediated immunity. c. both humoral and cell-mediated immunity. d.neither type of immunity.
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c. both humoral and cell-mediated immunity
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immunodeficiencies may result in an increased risk of infections by normally harmless microorganisms. These infections are referred to as: a. opportunistic. b. prophylactic. c. abnormal. d. transient.
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a. opportunistic
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19. Serious infections frequently occurring in patients with AIDS include: 1. tuberculosis. 2. Pneumocystis carinii pneumonia. 3. influenza. 4. tetanus. a. 1, 2 b. 1, 4 c. 2, 3 d. 3, 4
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a. 1, 2
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Which of the following statements does NOT apply to major histocompatibility complex (MHC) proteins or molecules? a. They are genes on chromosome 6. b.All members of a family have identical MHCs. c. They alert the immune system to virus-infected cells. d.A close match is essential for successful tissue transplants.
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b. All members of a family have identical MHCs.
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CD4-positive helper T cells function by: a.direct cytotoxic action. b. facilitating all immune system activity. c. producing immunoglobulins. d.inactivating allergens.
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b. facilitating all immune system activity.
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Host-versus-graft disease refers to: a.hyperacute rejection of tissue. b.T cells in grafted tissue attacking host cells. c.infection resulting from immunosuppression therapy. d.transplant rejection by the recipients immune system.
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d.transplant rejection by the recipients immune system.
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Which of the following complications does NOT occur frequently in AIDS patients? a.Kaposis sarcoma b.Wasting syndrome c. Lymphoma d. Polyarthritis
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d. Polyarthritis
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Which of the following characteristics apply to HIV? 1. It contains two strands of DNA. 2. It tends to mutate frequently to form new strains. 3. The incubation period is extremely short. 4. It is inactivated by heat and many disinfectants. a.1, 2 b.1, 3 c.2, 4 d.3, 4
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c.2, 4
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In cases of HIV infection, the window period refers to the time between: a. entry of the virus into the blood and the initial manifestations. b. entry of the virus into the body and the appearance of antibodies in the blood. c.entry of the virus into the body and a significant drop in CD4 T-helper lymphocyte count. d. diagnosis of HIV positive and diagnosis of AIDS.
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b. entry of the virus into the body and the appearance of antibodies in the blood
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Which of the following is an effect of cytokines? They: a. activate and stimulate proliferation of B and T lymphocytes. b. destroy antigens quickly. c. increase the rate of mitosis in tumors. d. cause immediate pain.
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a. activate and stimulate proliferation of B and T lymphocytes.
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What does seroconversion mean in relation to HIV and AIDS? a. The virus has been identified in the blood and body fluids. b. Antibodies for HIV have been identified in the blood. c. HIV was found in lymphocytes. d. Active infection has developed in the patient.
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b. Antibodies for HIV have been identified in the blood.
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Which of the following statements is TRUE regarding a patient who is HIV positive? a. No medication is required until the CD4 cell count drops below normal range. b. Antibodies are present, destroying the virus and preventing transmission to others. c. Antibodies in the blood indicate presence of virus and possible transmission to others. d.Enzymes have not yet converted RNA to DNA for replication.
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c. Antibodies in the blood indicate presence of virus and possible transmission to others.
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The term tolerance refers to: a. surveillance and destruction of new cancer cells by the immune system. b. the ability of the immune system to ignore self cells. c. the ability of T and B lymphocytes to work together. d. the role of lymphoid tissue in the body defenses.
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b. the ability of the immune system to ignore self cells.
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Which of the following statements applies to the complement system? a. It is activated by IgE. b. It blocks the inflammatory response. c. It consists of proteins in the blood that must be activated. d. It may destroy antibodies in the circulation.
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c. It consists of proteins in the blood that must be activated.
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Which of the following statements regarding immunoglobulins is TRUE? a.They consist of a unique sequence of amino acids. b.They are produced in the red bone marrow. c. They are attached to mucosal membranes at entry points into the body. d. IgA binds to allergens.
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a.They consist of a unique sequence of amino acids.
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Which of the following is NOT a cause of immunodeficiency? a.Hypoplasia of the thymus b.Delayed hypersensitivity c. Immunosuppressive drugs d. Atrophy of the lymph nodes
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b.Delayed hypersensitivity
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Which statement is TRUE regarding infants born to HIV-infected mothers? a. Infants usually test negative for HIV after birth. b. There is little risk of infected mothers passing the virus to their infants during delivery. c.Breast milk does not contain HIV or antibodies. d. Infants test positive for HIV because of the presence of maternal antibodies.
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d. Infants test positive for HIV because of the presence of maternal antibodies.
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The most common cause of death in patients who have AIDS is: a. HIV encephalopathy. b. tuberculosis. c. Pneumocystis carinii pneumonia. d. Candida infection.
answer
D Candida infection.
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Tissue transferred between two genetically identical twins is referred to as a/an: a.allograft. b.syngraft. c. isograft. d. autograft.
answer
c. isograft.
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