Case Study – Rheumatoid Arthritis – Flashcards

Unlock all answers in this set

Unlock answers
question
Which of the follow is not a characteristic of RA? Autoimmune Inflammatory Asymmetrical joint pain Females more commonly affected than males
answer
Asymmetrical joint pain is wrong. RA affects joints symmetrically
question
Which of the following is the most appropriate definition for RA? 1.Painful degenerative joint disease 2.Inflammatory reponse to deposition of crystals in joints 3.Inflammatory joint disease caused by autoimmune disorder
answer
3.Inflammatory joint disease caused by autoimmune disorder (1 is OA and 2 is gout)
question
What is RA called in children?
answer
Still's disease
question
What gene is common in 75% of patients?
answer
HLA DR4
question
What joints are most commonly affected first?
answer
MCPs, PIPs
question
True or false - can RA affect TMJ?
answer
True
question
True or false - does RA typically affect Tx and Lx?
answer
False, upper Cx is more commonly affected
question
As RA progresses, what can happen to the surrounding muscles?
answer
Muscle atrophy
question
Muscle atrophy and joint destruction can result in what?
answer
Joint instability and deformities
question
What part of the joint becomes swollen?
answer
Synovium
question
What is vascular granulation tissue across the cartilage also termed?
answer
Pannus - disrupts hyaline cartilage
question
Where can osteoporosis develop?
answer
In bones immediately adjacent to affected joints, especially in the fingers
question
Which of the following are NOT associated symptoms with RA? Multisystem disease Hyperplasia of lymphoid tissue with splenomegaly Cutaneous nodules Vasculitis Scleritis
answer
All of the symptoms are associated with RA
question
Diagnosis
answer
1. Morning stiffness greater than 1 hour of 6 wks duration 2. Pain/swelling of 3 or more joint areas, of 6 wks duration 3. Pain/swelling in hand joints, of 6 wks duration
question
Rheumatoid factor is present in patients with RA, true or false?
answer
True
question
What does the level of rheumatoid factor relate to?
answer
The severity of the disease
question
Most pts have raised levels of what?
answer
Serum immunoglobins (directed against rheumatoid factor)
question
What is ankylosis?
answer
Abnormal fusion of two bones. Can be seen on X-rays in pts with RA
question
What else is commonly viewed on pts X-rays with RA?
answer
Loss of articular cartilage (so there's increased friction in joints) and bone erosion
question
Which WBC can be found in the synovial fluid?
answer
Neutrophils
Get an explanation on any task
Get unstuck with the help of our AI assistant in seconds
New