Biochemistry – Rate Limiting Steps – Flashcards

Unlock all answers in this set

Unlock answers
question
What is the rate limiting step of de novo pyrimidine synthesis
answer
Aspartate transcarbamoylase (ATCase)
question
What is the rate limiting step of de novo purine synthesis
answer
Glutamine-PRPP amidotransferase
question
What is the rate limiting step of glycolysis
answer
Phosphofructokinase-1 (PFK-1)
question
What is the rate limiting step of gluconeogenesis
answer
Fructose-1,6-bisphosphatase (F-1,6-BP)
question
What is the rate limiting step of the TCA cycle
answer
Isocitrate dehydrogenase
question
What is the rate limiting step of glycogen synthesis
answer
Glycogen synthase
question
What is the rate limiting step of glycogenolysis
answer
Glycogen phosphorylase
question
What is the rate limiting step of the HMP shunt
answer
Glucose-6-phosphate dehydrogenase (G6PD)
question
What is the rate limiting step of fatty acid synthesis
answer
Acetyl-CoA carboxylase (ACC, sytrate=synthesis, uses citrate shuttle)
question
What is the rate limiting step of fatty acid oxidation
answer
Carnitine acyltransferase I (carnage, uses carnitine shuttle)
question
What is the rate limiting step of ketogenesis
answer
HMG-CoA synthase
question
What is the rate limiting step of cholesterol synthesis
answer
HMG-CoA reductase (inhibited by statins)
question
What is the rate limiting step of Heme synthesis
answer
ALA synthase
question
What is the rate limiting step of the urea cycle
answer
Carbamoyl phosphate synthase I
question
ATP produced by aerobic metabolism
answer
32 (heart and liver, malate-aspartate shuttle) or 30 (muscle, glycerol-3-phosphate shuttle)
Get an explanation on any task
Get unstuck with the help of our AI assistant in seconds
New