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Atorvastatin calcium C66H68CaF2N4O10 structure – Flashcards

Flashcard maker : August Dunbar

Contents

Experimental Melting Point:
Experimental Solubility:
Safety:
Bio Activity:

Molecular Formula	C₆₆H₆₈CaF₂N₄O₁₀
Average mass	1155.342 Da
Density
Boiling Point
Flash Point
Molar Refractivity
Polarizability
Surface Tension
Molar Volume

Experimental data
Predicted – ACD/Labs
Predicted – ChemAxon

Experimental Physico-chemical Properties
- Experimental Melting Point:
  
  176-178 °C BIONET-Key Organics GS-3563
- Experimental Solubility:
  
  Soluble to 100 mM in DMSO Tocris Bioscience 3776

Miscellaneous

Safety:

IRRITANT Matrix Scientific 097734

Sold for research purposes under agreement from Pfizer Inc. Tocris Bioscience 3776

Bio Activity:

Enzymes Tocris Bioscience 3776

HMG-CoA Reductase Tocris Bioscience 3776

Potent HMG-CoA reductase inhibitor Tocris Bioscience 3776

Potent HMG-CoA reductase inhibitor (IC50 = 8 nM). Reduces circulating LDL-C by inhibiting cholesterol biosynthesis and inducing expression of LDL receptors. Inhibits smooth muscle cell proliferation i
n vitro and exhibits antinociceptive effects in the inflammatory hypernociception model. Tocris Bioscience 3776

Potent HMG-CoA reductase inhibitor (IC50 = 8 nM). Reduces circulating LDL-C by inhibiting cholesterol biosynthesis and inducing expression of LDL receptors. Inhibits smooth muscle cell proliferation in vitro and exhibits antinociceptive effects in the inflammatory hypernociception model. Tocris Bioscience 3776

Reductases Tocris Bioscience 3776

Predicted data is generated using the ACD/Labs Percepta Platform – PhysChem Module

No predicted properties have been calculated for this compound.

Density:
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction:
Molar Refractivity:
#H bond acceptors:
#H bond donors:
#Freely Rotating Bonds:
#Rule of 5 Violations:

ACD/LogP:
ACD/LogD (pH 5.5):
ACD/BCF (pH 5.5):
ACD/KOC (pH 5.5):
ACD/LogD (pH 7.4):
ACD/BCF (pH 7.4):
ACD/KOC (pH 7.4):
Polar Surface Area:
Polarizability:
Surface Tension:
Molar Volume:

Click to predict properties on the Chemicalize site

Atorvastatin calcium C66H68CaF2N4O10 structure – Flashcards

Experimental Melting Point:

Experimental Solubility:

Safety:

Bio Activity:

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