The availability of venture capital is frequently cited as a significant factor in the differing development of biotechnology in the USA, Europe, and Japan. It is widely believed that a scarcity of venture capital hindered the creation of biotechnology startups outside the U.S. Venture capital, largely an American institution, undoubtedly played a significant role in propelling the expansion of new biotechnology firms, also known as "NBFs".
In Europe, there were numerous sources of funding besides venture capital for start-ups, often in the form of government programs. Despite the crucial role of venture capital in establishing biotech firms in the US, collaborations between these newer firms and larger, established companies may have offered an even more significant source of capital.
(Malerba, Orsenigo; 2005 p. 13) A company's long-term success is heavily reliant on its ability to innovate, which can significantly alter its c
...ompetitive position by weakening or toppling market leaders, promoting new players, and establishing fresh market leaders. For instance, Xerox rose from obscurity to rule the copier industry with their innovative plain paper copying technology. Similarly, Kodak became a photography giant by introducing revolutionary celluloid roll cameras. Conversely, Underwood and Remington lost their dominant positions in the market when they fell behind in adopting the latest technology.
Although extensive research has been conducted, it is still uncertain which size of company excels in product innovation - small, medium or large. Nonetheless, size can have a significant impact on this procedure. The ability to replace specialized investments may be a critical driving force for achieving groundbreaking product innovation within an organization. These investments could be either physical or organizational and are closely associated with a particular produc
technology, distinguishing companies with impressive records of innovation from those without.
Although prioritizing innovation may lead to the loss of value in existing specialized investments, innovative organizations still pursue it even if it means cannibalizing their current investments. In contrast, non-innovative organizations are hesitant to do so. Companies that heavily invest in specialized technology become less willing to cannibalize these investments and this applies particularly to large, established organizations in a product market that have invested significantly in older product technologies. Consequently, such firms are generally less inclined towards innovation when all other factors are held constant.
It is not necessarily true that established companies with specialized technology and outdated methods will fail. Research indicates that these companies can overcome their resistance to change by incorporating three crucial organizational elements: 1) vibrant inner markets, 2) influential product champions, and 3) foresight into future market demands. Thriving inner markets promote autonomy among business unit managers and encourage competition between units. Companies with influential product champions have systems that support the efforts of those champions.
According to Crespi (2004), companies that prioritize future market research and decision-making focus on potential customers and competitors rather than existing ones. Larger firms with this approach are not afraid to cannibalize, despite having significant investments in specialized areas. These findings challenge common beliefs about organizational size, core competencies, synergy, and cannibalization.
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