question

When chemotherapy is used before primary treatment (surgery) to reduce the size of a solid tumor, it is called what?

answer

Neoadjuvant Therapy

question

Which of the following class of drugs is cell cycle non-specific and therefore can affect the cancer in any phase of the cell cycle?

answer

Alkylating Agents

question

Mutations in genetic material from exposure to chemotherapy are termed?

answer

Genotoxicity

question

The Vinca Alkaloids act in which phase where they prevent cell division?

answer

M Phase

question

Which of the following is likely the best way to ensure patient adherence to oral chemotherapy?

answer

Schedule a phone call with the patient 3-5 days after therapy is initiated

question

To address the dose-limiting toxicity of cyclophosphamide, what should discharge education for the patient include?

answer

Encourage the intake of 2-3 liters of fluid per day

question

Which of the following is true and should always be included in your discussion with patients when they go home after completing chemotherapy?

answer

Sexual relations are often allowed as long as special precautions are taken

question

Your patient asks if it is okay to have contact with family members during chemotherapy treatments. your best response is:

answer

Normal contact and hugging and kissing are safe

question

Your patient had an extravasation, which is a vinca alkaloid class of chemotherapy. What do you teach them about caring for the site when they get home?

answer

Apply a warm compress for 15 minutes, 4 times a day

question

Which of the following actions reflect an understanding of safe-handling procedures?

answer

Wear two pairs of chemotherapy-tested gloves and gown when handling HD exposed bodily fluids

question

Which of the following is TRUE about the use of chemotherapy gowns with administration of chemotherapy/biotherapy?

answer

Gowns should be worn while administering chemotherapy by IV, oral (if splashing is likely), topical, intracavitary, and if giving aerosolized drugs

question

Because of the possibility of exposure through bodily fluids, what is the minimum amount of time to maintain hazardous drug precautions?

answer

48 hours

question

The nurse wearing a chemotherapy gown and gloves has assisted in cleaning an incontinent patient with chemotherapy infusing. The gown does not appear soiled. What should be done with the gown?

answer

Dispose in a yellow chemotherapy waste container

question

Which of the following is true about pregnant nurses who care for patients receiving chemotherapy?

answer

Employee has the responsibility to notify employer of pregnancy

question

PPE is required when administering chemotherapy using which of the following routes of administration? SATA

answer

Select all answers.

question

When caring for the patient who is receiving chemotherapy, you notice a puddle of urine beneath the foley bag on the floor. What should be your first action?

answer

Remove unnecessary people from the area

question

Which of the following may be included in a medical surveillance program?

answer

Administer periodic questionnaires tracking contact with HD, use of PPE, and adverse events

question

The NCCN guidelines recommend that with the agent you are administering that you should give the following three drug combination as antiemetic premedication: 1. 5-HT3 Antagonist 2. NK1 Antagonist 3. Corticosteroid

answer

High emetic risk

question

Prior to beginning any chemotherapy treatment, the nurse must perform an assessment where which of the following should occur?

answer

Discussion with the patient about a history of drug, allergic, or transfusion reactions

question

Certain chemotherapy agents are safely administered intrathecally but which of the following should NEVER be administered intrathecally as it is almost certain to be fatal?

answer

Vincristine

question

What is the very first thing you should do if you suspect a drug extravasation?

answer

Stop the infusion

question

Prevention of infection is so important for most oncology patients. Which of the following is no longer recommended to prevent infection?

answer

Neutropenic Diet

question

Which of the following is true about closed-system transfer devices?

answer

Use of full PPE is still required

question

If you are administering a chemotherapy agent that is an irritant know to have some vesicant properties, which of the following is true?

answer

Treat an extravasation like it is a vesicant

question

Out of the following, which is the safest way to administer vesicant therapy?

answer

MOST LIKELY: IV push via the free flow method DEFINITELY NOT: Short infusion over 2 hours OR IV Continuous Infusion

question

Which of the following is a concern when using oral chemotherapy agents?

answer

Ensuring adherence to prescribed therapy

question

With which of the following agents would the nurse need to educate the patient about ways to prevent acute, reversible neuropathy exacerbated by cold temperatures?

answer

Oxiplatin

question

You are educating your patient about febrile neutropenia. You discuss that febrile neutropenia is defined as an oral temperature greater than 100.4 lasting at least one hour with an ANC less than:

answer

500

question

You are discussing the advantages and disadvantages of oral chemotherapy with your patient. What is one of the advantages of oral chemotherapy that can ultimately lead to adherence issues with this type of therapy?

answer

MOST LIKELY: Patient has an increased sense of control over treatment DEFINITELY NOT: Dosing schedules are straightforward... OR The convenience for the patient of taking medication at home

question

Which of the following is often overlooked or sometimes even not included in the routine two-nurse check of chemotherapy orders?

answer

Cumulative Dose

question

IV access is needed for a continuous infusion of vincristine and doxorubicin. Of the choices below, which would be the best location to infuse this treatment?

answer

Peripherally inserted central catheter with strong blood return

question

You know from reviewing the ONS PEP resources on skin reactions, that the only intervention that is likely to be effective is/

answer

MOST LIKELY: Dose interruption or modification (on ONS website) DEFINITELY NOT: Antibiotics

question

Your patient has just arrived and is neutropenic and has a fever of 101.5. What is the most important thing to do after you obtain the ordered cultures?

answer

Administer empiric, broad spectrum antibiotics

question

According to the ONS position "Education of the Nurse Administers and Cares for the Individual Receiving Chemotherapy and Biotherapy", which of the following is necessary of the nurse who administers chemotherapy?

answer

They complete both a didactic component and a clinical practicum to chow competency with administration principles.

question

Which of the following is the only time it is acceptable to take a verbal order?

answer

Stop or hold chemotherapy

question

Which statement describes how chemotherapy works?

answer

Disrupts the cell cycle during reproduction

question

The benefits of combination therapy include:

answer

Synergistic effect between drugs

question

According to the ONS chemotherapy and biotherapy guidelines and recommendations for practice and the ONS/ASCO chemotherapy administration safety standards, how often should education and competency evaluation regarding chemotherapy administration be performed?

answer

When hired and annually thereafter

question

You are scheduling a meeting to remind the staff about the proper use of PPE to ensure decreased risk of HD exposure. who, besides the nurses, should attend?

answer

All of the above.

question

Which of the following safeguards should be taken to better prevent exposure to HD?

answer

Flush the toilet with the lid down or place a plastic backed pad over the toilet

question

When intrathecal chemotherapy is prepared for administration, what additional safety step beyond the usual chemotherapy safety checks, must be followed?

answer

Specialized labeling and handling

question

If a nurse is pregnant or breastfeeding, the ASCO/ONS recommendation is for the employer to?

answer

Offer alternative duty to protect against HD exposure

question

If you have an accidental exposure of HD on your clothes and skin, what should be your first or initial response?

answer

Remove the affected clothing immediately

question

When is it necessary to wear a NIOSH-approved respirator?

answer

When cleaning up a hazardous drug spill

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