Natural History of Disease – Flashcards

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Natural History of Disease
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Referred to the course of the disease over time, unaffected by treatment. DISEASE IS AN EVOLVING PROCESS Stages 1. Stage of Susceptibility 2. Stage of Pre-Symptomatic Disease 3. Stage of Clinical Disease 4. Stage of Disability
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Stage of Susceptibility
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- Disease has not developed -Risk factors promote development (poor diet, lack of exercise, stress, high cholestorol level,etc.)
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Risk Factors
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Factors that will favor the disease's development Two types: Modifiable and Non-modifiable
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Modifiable Risk factors
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Changeable factors Lifestyle: Centenarians (exercise, diet rich in fruits and vegetables, friends, purpose in life) Obesity: Weight Smoking: lung cancer: 2nd most common cancer
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Non-modifiable factors
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Factors that cannot be changed Premature babies: at risk for mental retardation disability, chronic lung disease and learning disabilities Age and genetics: Heart disease, Parkinson's disease, Alzheimer's disease Race: -Black Americans have higher incidence for HTN, diabetes and coronary heart disease: risk for stroke -Mexicans have high incidence of diabetes (higher mortality) -Native Americans have higher incidence of alcoholism, lower incidence of heart disease Genetics
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Stage of Pre-Symptomatic Disease
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- No manifestations (clinical signs and symptoms) of the disease -Pathological changes have started to occur Examples: -High Cholesterol: plaque formation -High Stress Level: develop pre-hypertension -Pre-cancerous mole: atypical cells -Pre-diabetes: chronic elevation of blood glucose levels
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Stage of Clinical Disease
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-Organ changes have occured (now there are recognizeable signs and symptoms of the disease) -Subdivided into 3 stages (Morphological, Functional or Therapeutic)
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Morphological
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Involves the CELLULAR level -Most often used with CANCER -Measures extent of disease (Ex: tumor staging) -Allows for prognosis Tumors placed into categories Localized Regional Metastasis Metastasis
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Localized
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1 single lymph node or organ is involved
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Regional Metastasis
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Group of lymph nodes near organ on SAME SIDE of diaphragm
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Metastasis
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Involves BOTH SIDES of diaphragm
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Functional
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Involves the stages or types of disease -Based on extent of disease Examples -Types of Diabetes (Insulin vs Non-Insulin dependent) -Stages of Alzheimers (7 stages) -Stages of Hypertension
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Therapuetic
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Involves the TREATMENT -Based on restrictions Examples -Heart disease (Restriction of activity, dietary restrictions) -Diabetes (Dietary or caloric restriction)
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The Importance of Staging
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Is for epidemiologic studies in research Reduces variability in -evaluation of the effect of treatments -clinical trials -management of clients
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Stage of Disability
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Any temporary or long term reduction of a person's activities, including his psychosocial role as parent, wage earner and member of his community Emphasis is on LOSS OF FUNCTION, not the structural defect Examples -Diabetes leads to blindness, amputation, renal failure or cardiac disease -Hypertension leads to stroke and paralysis -COPD and heart disease leads to impairment of activity
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Levels of Prevention
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Leavell and Clark (1965) Disease EVOLVES over time. Pathological changes may or may not become fixed and irreversible. The aim of prevention is to DETECT and INTERVENE at the RISK FACTORS. Basis of all prevention programs
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3 Levels of Prevention
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Primay Prevention Secondary Prevention Tertiary Prevention
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Primary Prevention
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-Focuses on health promotion and protection -Occurs in the stage of SUSCEPTIBILITY
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Secondary Prevention
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-Identifying a health problem and its intervention -Occurs in the stage of PRE-CLINICAL and CLINICAL
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Tertiary Prevention
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-Focuses on restoration and rehabilitation -Occurs in the stage of DISABILITY
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Primary Prevention (2)
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Health Promotion -AVOIDANCE of disease -Motivated by personal approach to wellness -WELLNESS focused Protection against specific health problems -Behaviors to actively avoid illness (immunizations, taking vitamins, handwashing) -Health promotion programs (exercise programs, nutrition programs, fire safety, D.A.R.E program)
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Secondary Prevention (2)
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-Early identification of health problems (Goal -> identify people in early stages of disease and limit disability -Interventions to alleviate health problems (ex: screenings, physical exam, dental checks, assessment of growth and development) Examples: -Annual pap smear -Mammogram -Self-breast exam -Self-testicular exam -Falls risk -ROM -Turn patients Q 2
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Tertiary Prevention
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-Begins after an illness or disability (is fixed and stabalized) -Helps rehabilitate or restore client to optimal level of health within the constraints of the disability Examples: -Physical therapy -Cardiac rehab -Support group after cholestomy -Teaching diabetic how to prevent complications
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Schematic Representation of Natural History of Disease and Levels of Prevention (Chart)
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Pg 133
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Theories Used in Health Promotion
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Needs Theory Developmental Theory Theoretical Frameworks
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Needs Theory
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Maslow (See pg. 134)
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Needs Theory (Richard Kalish)
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-Adapted Maslow's theory (6 Levels) -Included category between physiological and safety needs (STIMULATION NEEDS)
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Developmental Stage Theory: Piaget, Erickson
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-Describes characteristics of people in a certain group Usefulness in Nursing: -Describes a typical behavior within a certain group -Predicts behavior in a given circumstance -Used in clinical education
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Healthy People 2010 (Purpose)
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Provided framework for national health promotion, health protection and prevention
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Healthy People 2010 (Goals)
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-Increase quality and years of life -Eliminate health disparities
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Health (Tradition definition)
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The presense or abscense of disease
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Health (WHO definition)
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A state of complete physical, mental and social well-being and not merely the abscense of disease and infirmity
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Wellness
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State of well-being
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5 Models of Wellness
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Clinical model Role Performance model Adaptive Model Eudemonistic model Agent-host envrironmental model
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Clinical model
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-PHYSIOLOGICAL aspect of health -absence of signs and symptoms -Disease is narrow model
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Role performance model
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Ability to fullfil societal's needs
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Adaptive model
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-Disease is a failure in adaptation -Aim of treatment is to restore the ability to adapt
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Eudemonistic model
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-Based on self-actualization (Maslow's Theory) -Health is seen as self-actualization -Illness prevents actualization (client potential)
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Agent-host environmental model
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-Considers multiple causes of disease -Used to predict illness -Identifies risk factors which result from agent, host and environment
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Health Illness Continua
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Consists of grids or graduated scales -Used to measure a client's perceived level of health and illness are on opposite ends Dunn's High Level of Wellness Grid (See Pg. 137) Travis' Illness Wellness Continuum (See Pg. 138)
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