Identifying a Constituent of Panacetin Essay Example

the crystals turned out to be significantly more white, crystalline and shiny than those from Experiment 2. After spending three minutes in the ice bath, the crystals almost completely filled the flask, though still immersed in fluid. As we poured the mixture onto the filter paper, some of it accidentally spilled causing a loss of certain unidentified substances. Most of it seemed to comprise fluid with lesser crystals though. Furthermore, when rinsing the filtrate with cold water, ice got onto the filter delaying us for a while as we had to wait for the ice to melt so as not to taint the weight excessively. The filtrate produced had a frothy character as it seeped through, appearing extremely bubbly until it hit bottom of the flask and turned back into fluid. The presence of diminutive crystals was observed in the liquid.

In the course of our analysis, we determined the melting points of both the initial and secondary substances to be within 127 and 137 degrees Celsius. This was achieved using a Mel-Temp instrument that began at 90 degrees and ended at 140 degrees Celsius. Regarding the third part involving an unknown substance, the tool commenced at 90 degrees and finished at 120 degrees, recording a melting point range from 80-90.4. In the last part of our study concerning another unidentified substance, we launched operations on the device starting with a temperature of 100, concluded it at 140 degrees while identifying a temperature range between111-133.8 Celsius which indicated its melting point.

Outcomes and Dialogue

In the beginning, our unknown purify substance weighed 1.49 g, which subtracted from the initial 1.58g of unpurified

solid indicates a loss of .09 g associated with impurities. The weights of the filter paper and the watch glass were .33g and 50.56 g, summing up to 52.38 grams in total. Our refined calculation of the unknown purify substance's weight involved adding the weights of the watch glass and filter paper, then subtracting that from the total which yielded 1.49 grams. This value was then deducted from the initial substance mass to determine the impurities misplaced. This experiment did not entail a high volume of computational work.

We initiated the Mel-Temp apparatus at 90 and ceased it at 120 for the third compound because an unknown substance was introduced to the acetanilide. Given that acetanilide's melting point is established at 114, this seemed an appropriate range. Nevertheless, we observed the melting point range of this compound to be between 80-90.4, which led us to conclude that the unidentified substance was mixed with acetanilide but was not an acetanilide itself. This deduction is based on the principle that mixing different compounds lowers the melting point of the known compound, which in this case is markedly lesser than its original.

The unknown substance blended with phenacetin in the fourth part of the compound displayed a melting point range from 111 to 133.8. This range closely correlates with the known melting point of phenacetin, which sits at 135. Therefore, it strongly suggests a chemical resemblance between the unknown additive and phenacetin, especially since the melting point wasn't diminished. This corroborates further when considering that the self-mixture of the unknown substance (parts one and two) manifested a melting point range of 127-137.

Considering that 129

mL of boiling water was required to dissolve the unidentified compound during purification, and with prior knowledge that this particular volume is essential for phenacetin dissolution, it's plausible to propose that the mysterious compound could be Phenacetin. Therefore, we can assert with certainty that Phenacetin might be the secret component in Panacetin.

The unidentified pharmaceutical compound was subjected to experimental recrystallization, which was facilitated by boiling the compound in minimal water until it fully dissolved. After complete dissolution, the solution was allowed to cool to room temperature. The recrystallization process was then initiated by scratching the walls of the container using a stirring rod as the solution cooled. Following this, the compound was transferred to an ice bath. The resolidified drug was collected via vacuum filtration, after which it was rinsed with a small dosage of ice-cold water. The product was repeatedly dried until its weight remained constant and was then gauged in a tared vial. Subsequently, the unidentified substance (now a solid) was pulverized into fine particles using a spatula and a watch glass.

The solid was divided into four approximately equal divisions. The first and second divisions were merged, while the third division was comprehensively mixed with a similar quantity of acetanilide. The fourth division was consequently uniformly blended with an identical proportion of phenacetin. Next, melting point ranges of the four divisions were ascertained. The temperature readings were recorded at two crucial stages: first when the initial signs of liquidation were observed, and next when each portion turned entirely into liquid. Subsequently, the final product was submitted and identified based on its actual product name as suggested by the derived

results.