Home Page Flashcards sodium picosulfate C18H13NNa2O8S2 structure - Flashcards

sodium picosulfate C18H13NNa2O8S2 structure – Flashcards

Flashcard maker : Marguerite Castillo

Contents

Experimental Solubility:
Bio Activity:

Molecular Formula	C₁₈H₁₃NNa₂O₈S₂
Average mass	481.407 Da
Density
Boiling Point
Flash Point
Molar Refractivity
Polarizability
Surface Tension
Molar Volume

Experimental data
Predicted – ACD/Labs
Predicted – ChemAxon

Experimental Physico-chemical Properties
- Experimental Solubility:
  
  10 mM in DMSO MedChem Express HY-B0544
  
  DMSO 100 mg/mL; Water 90 mg/mL MedChem Express HY-B0544

Miscellaneous

Bio Activity:

Others MedChem Express HY-B0544

Sodium Picosulfate inhibits absorption of water and electrolytes, and increases their secretion. MedChem Express

Sodium Picosulfate inhibits absorption of water and electrolytes, and increases their secretion.; Target: Others; Sodium Picosulfate displays cytotoxic effects on cultured liver cells. MedChem Express HY-B0544

Sodium Picosulfate inhibits absorption of water and electrolytes, and increases their secretion.;Target: Sodium Picosulfate displays cytotoxic effects on cultured liver cells. 800 and 1600 mg/mL induces dose-dependently vacuolic and fatty change as well as necrosis combined with a lowered mitotic activity and a slight increase in LDH values of the rapidly growing cultured liver cells of rabbit. Comparable but less severe effects are observed in 4-day old liver cell cultures of rat, while liver cells cultured for 6 to 11 days tolerate 1600 mg/mL Sodium Picosulfate. In human liver cultures the number of cells is slightly lowered at 800 and 1600 mg/mL and the number of nuclei in division is decreased dependent on dose [1]. Sodium Picosulphate has no major influence on ileal and colonic epithelial cell proliferation. In a 12 weeks study, 10 mg/kg Sodium Picosulphate continuously treatment does not influence the labeling index of Brdu (LI) in the ileum and induces no statistically MedChem Express HY-B0544

Predicted data is generated using the ACD/Labs Percepta Platform – PhysChem Module

No predicted properties have been calculated for this compound.

Density:
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction:
Molar Refractivity:
#H bond acceptors:
#H bond donors:
#Freely Rotating Bonds:
#Rule of 5 Violations:

ACD/LogP:
ACD/LogD (pH 5.5):
ACD/BCF (pH 5.5):
ACD/KOC (pH 5.5):
ACD/LogD (pH 7.4):
ACD/BCF (pH 7.4):
ACD/KOC (pH 7.4):
Polar Surface Area:
Polarizability:
Surface Tension:
Molar Volume:

Click to predict properties on the Chemicalize site

sodium picosulfate C18H13NNa2O8S2 structure – Flashcards

Experimental Solubility:

Bio Activity:

Haven't found what you were looking for?

Search for samples, answers to your questions and flashcards