Arixtra/Lovenox/Heparin – Flashcards
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Arixtra
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Contraindications: Patients with crcl <30 ml/min Active major bleeding Hemodylasis Thrombocytopenia with this medication Bacterial endocarditis
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Lovenox
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Contraindications: Major bleeding Hypersensitivity to enoxaprin, heparin or pork Thrombocytopenia with positive vitro test (HIT) Hemodialysis Bacterial endocarditis
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Arixtra
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Precautions: low weight pts <50 kg age: over 75 Concomitant use of antiplatlets Epidural/spinal anesthesia Brain/spring/eye surgery
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Lovenox
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Precautions: crcl < 30 ml/min adjust dose Low weight pts < 50kg Age over 75 Epidural/spinal anesthesia Brain/spring/eye surgery
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Arixtra/lovenox cautions
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Platlet count <100,000 arixa should be d/c -No Arixtra or Lovenox for 24hrs prior to epidural catheter spinal anesthesia administration -No Arixtra or Lovenox during epidural catheter insertion and for 24hrs after catheter removal or after spinal block administratio
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Fondaparinux (Arixtra) (SC)
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Indications: Prevention of DVT Post Knee/Hip Surgery
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Fondaparinux (Arixtra) (SC)
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Treatment of DVT w/ or w/out PE in conjunction w/ warfarin (bridge) •Beginning on lovenox/arixtra to maintain on coumadin
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Arixtra /Lovenox Lab Monitoring
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Daily ACP, CBC •Baseline serum creatinine within 24hrs of first dose is required
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Nursing considerations
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Do Not Remove air bubble •Administer in anterolateral abdominal wall, alternating injection sites. •Call MD immediately if Hematoma develops at injection sites (do not rub)
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Reversal Agent Lovenox
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protamine sulfate
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Reversal Agent Arixtra
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no known reversal agent
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Heparin
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Prophylaxis: •SC •Usual dose 5000 units q8h-q12h •Uses: DVT prophylaxis
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Heparin treatment
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IV, continous infusion •Adjustment based on aptt. Target = 60-90 seconds. (1.5-2 greater than normal).
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Reversal agent heparin
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Protamine Sulfate 1mg for every 100units Heparin on board
