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Home Page Flashcards Venlafaxine hydrochloride C17H28ClNO2 structure - Flashcards

Venlafaxine hydrochloride C17H28ClNO2 structure – Flashcards

Flashcard maker : Brenda Gannon

Molecular Formula C17H28ClNO2
Average mass 313.863 Da
Density
Boiling Point
Flash Point
Molar Refractivity
Polarizability
Surface Tension
Molar Volume
  • Experimental data
  • Predicted – ACD/Labs
  • Predicted – ChemAxon
  • Predicted – Mcule
  • Experimental Physico-chemical Properties

    • Experimental Melting Point:

      217 °C TCI V0110
      215 °C LKT Labs
      [V1854]

    • Experimental Solubility:

      DMSO:47mg/mL MedChem Express HY-B0196A
      Soluble in water and DMSO Axon Medchem 1727
      Soluble in water. LKT Labs
      [V1854]
      Soluble to 100 mM in water and to 50 mM in DMSO Tocris Bioscience 2917
  • Predicted Physico-chemical Properties

    • Predicted Melting Point:

      217 °C TCI
      217 °C TCI V0110
  • Miscellaneous

    • Safety:

      36/37/38 LKT Labs
      [V1854]
      5 Axon Medchem 1727
      H303;H313;H317;H333;H334;H335;H373 Axon Medchem 1727
      H319 LKT Labs
      [V1854]
      no pictogram Axon Medchem 1727
      P101;P102;P103;P260;P262;P263;P264;P270;P280;P304;P312;P340 Axon Medchem 1727
      Warning Axon Medchem 1727
      Xi LKT Labs
      [V1854]

    • Target Organs:

      5-HT Receptor antagonist TargetMol T0472

    • Drug Status:

      approved BIONET-Key Organics KS-5049

    • Bio Activity:

      5-HT Receptor TargetMol T0472
      5-HT Transporters Tocris Bioscience 2917
      Dual serotonin/noradrenalin re-uptake inhibitor Tocris Bioscience 2917
      Dual serotonin/noradrenalin re-uptake inhibitor that displays ~ 30-fold higher affinity for SERT than NET (Ki values are 82 and 2480 nM respectively). Antidepressant; increases swimming and climbing b
      ehavior in the forced-swim test in rats. Tocris Bioscience 2917
      Dual serotonin/noradrenalin re-uptake inhibitor that displays ~ 30-fold higher affinity for SERT than NET (Ki values are 82 and 2480 nM respectively). Antidepressant; increases swimming and climbing behavior in the forced-swim test in rats. Tocris Bioscience 2917
      Neuronal Signaling MedChem Express HY-B0196A
      Neuronal Signaling; MedChem Express HY-B0196A
      Neuroscience TargetMol T0472
      Neurotransmitter Transporters Tocris Bioscience 2917
      SSRIs MedChem Express HY-B0196A
      Transporters Tocris Bioscience 2917
      Venlafaxine hydrochloride is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. MedChem Express
      Venlafaxine hydrochloride is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class.; Target: SNRI; Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. MedChem Express HY-B0196A
      Venlafaxine hydrochloride is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class.;Target: SNRIVenlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. First introduced by Wyeth in 1993, now marketed by Pfizer, it is licensed for the treatment of major depressive disorder (MDD), as a treatment for generalized anxiety disorder, and comorbid indications in certain anxiety disorders with depression. In 2007, venlafaxine was the sixth most commonly prescribed antidepressant on the U.S. retail market, with 17.2 million prescriptions.Venlafaxine is a bicyclic antidepressant, and usually categorized as a serotonin-norepinephrine reuptake inhibitor (SNRI), but it has been referred to as a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). It works by blocking the transporter reuptake proteins for key neurotransmitters affecting mood, thereby leaving more active neurotransmitters in the synapse. The neurotr MedChem Express HY-B0196A

Predicted data is generated using the ACD/Labs Percepta Platform – PhysChem Module

No predicted properties have been calculated for this compound.

Density:
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction:
Molar Refractivity:
#H bond acceptors:
#H bond donors:
#Freely Rotating Bonds:
#Rule of 5 Violations:
ACD/LogP:
ACD/LogD (pH 5.5):
ACD/BCF (pH 5.5):
ACD/KOC (pH 5.5):
ACD/LogD (pH 7.4):
ACD/BCF (pH 7.4):
ACD/KOC (pH 7.4):
Polar Surface Area:
Polarizability:
Surface Tension:
Molar Volume:

Click to predict properties on the Chemicalize site

  • 1-Click Docking
  • 1-Click Scaffold Hop

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