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umifenovir hydrochloride C22H26BrClN2O3S structure – Flashcards

Flashcard maker : Tony Foust

Contents

Experimental Melting Point:
Experimental Solubility:
Safety:
Bio Activity:

Molecular Formula	C₂₂H₂₆BrClN₂O₃S
Average mass	513.875 Da
Density
Boiling Point
Flash Point
Molar Refractivity
Polarizability
Surface Tension
Molar Volume

Experimental data
Predicted – ACD/Labs
Predicted – ChemAxon

Experimental Physico-chemical Properties
- Experimental Melting Point:
  
  133 °C Biosynth J-501287
  
  133-137 °C (Decomposes) LabNetwork LN00191929
- Experimental Solubility:
  
  DMSO 48 mg/ml MedChem Express HY-14904A
  
  in DMSO > 10 mM MedChem Express HY-14904A

Miscellaneous

Safety:

IRRITANT Matrix Scientific 092967

Bio Activity:

Anti-infection MedChem Express HY-14904A

Anti-infection; MedChem Express HY-14904A

Arbidol (Umifenovir) hydrochloride is an broad-spectrum antiviral chemical agent which can inhibit cell entry of enveloped viruses by blocking viral fusion with host cell membrane MedChem Express

Arbidol (Umifenovir) hydrochloride is an broad-spectrum antiviral chemical agent which can inhibit cell entry of enveloped viruses by blocking viral fusion with host cell membrane;IC50 value:;Target: Antiviral; Anti-influenza agent;In vitro: Arbidol was found to present potent inhibitory activity against enveloped and non-enveloped RNA viruses, including FLU-A, RSV, HRV 14 and CVB3 when added before, during, or after viral infection, with 50% inhibitory concentration (IC50) ranging from 2.7 to 13.8 microg/ml.However, arbidol showed selective antiviral activity against AdV-7, a DNA virus, only when added after infection (therapeutic index (TI) = 5.5) [1]. Arb interacts with the polar head-group of phospholipid at the membrane interface. Fluorescence studies of interactions between Arb and either tryptophan derivatives or membrane peptides reconstituted into liposomes show that Arb interacts with tryptophan in the micromolar range. Interestingly, apparent binding affinities between l MedChem Express HY-14904A

Influenza Virus MedChem Express HY-14904A

Predicted data is generated using the ACD/Labs Percepta Platform – PhysChem Module

No predicted properties have been calculated for this compound.

Density:
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction:
Molar Refractivity:
#H bond acceptors:
#H bond donors:
#Freely Rotating Bonds:
#Rule of 5 Violations:

ACD/LogP:
ACD/LogD (pH 5.5):
ACD/BCF (pH 5.5):
ACD/KOC (pH 5.5):
ACD/LogD (pH 7.4):
ACD/BCF (pH 7.4):
ACD/KOC (pH 7.4):
Polar Surface Area:
Polarizability:
Surface Tension:
Molar Volume:

Click to predict properties on the Chemicalize site

umifenovir hydrochloride C22H26BrClN2O3S structure – Flashcards

Experimental Melting Point:

Experimental Solubility:

Safety:

Bio Activity:

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