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Trazodone Hydrochloride C19H23Cl2N5O structure – Flashcards

Flashcard maker : Ruth Blanco

Contents

Experimental Melting Point:
Experimental Solubility:
Safety:
Target Organs:
Drug Status:
Compound Source:
Bio Activity:

Molecular Formula	C₁₉H₂₃Cl₂N₅O
Average mass	408.325 Da
Density
Boiling Point
Flash Point
Molar Refractivity
Polarizability
Surface Tension
Molar Volume

Experimental data
Predicted – ACD/Labs
Predicted – ChemAxon
Predicted – Mcule

Experimental Physico-chemical Properties
- Experimental Melting Point:
  
  223-226 °C LabNetwork LN00189344
- Experimental Solubility:
  
  10 mM in DMSO MedChem Express HY-B0478
  
  DMSO 1 mg/mL; Water <1 mg/mL MedChem Express HY-B0478

Miscellaneous

Safety:

IRRITANT Matrix Scientific 090825
Target Organs:

Serotonin uptake inhibitor;5-HT receptor antagonist;Adrenergic Receptor antagonist ;Histamine Receptor TargetMol T1619
Drug Status:

approved BIONET-Key Organics KS-5100
Compound Source:

synthetic Microsource
[01503121]

Bio Activity:

5-HT Receptor MedChem Express HY-B0478

GPCR/G protein MedChem Express HY-B0478

GPCR/G protein; Neuronal Signaling; MedChem Express HY-B0478

Neuroscience TargetMol T1619

Sodium-dependent serotonin transporter;5-HT receptor;Adrenergic receptor;Histamine H1 receptor TargetMol T1619

Trazodone HCl is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders. MedChem Express

Trazodone HCl is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders.;Target: 5-HT Receptor;Trazodone is a triazolopyridine derivative, chemically and pharmacologically unrelated to other currently available antidepressants. Trazodone has been successfully used in a small number of patients with depression and pre-existing cardiovascular disease. trazodone has also been used as a hypnotic for psychotropic-induced or other insomnias with some success [1]. Trazodone is an effective hypnotic for patients with antidepressant-associated insomnia [2]. Trazodone may be helpful in men with erectile dysfunction (ED), possibly more so at higher doses, and in men with psychogenic ED. Future high-quality trials should compare trazodone with placebo and other therapies in men with depression and psychogenic ED [3]. MedChem Express HY-B0478

Predicted data is generated using the ACD/Labs Percepta Platform – PhysChem Module

No predicted properties have been calculated for this compound.

Density:
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction:
Molar Refractivity:
#H bond acceptors:
#H bond donors:
#Freely Rotating Bonds:
#Rule of 5 Violations:

ACD/LogP:
ACD/LogD (pH 5.5):
ACD/BCF (pH 5.5):
ACD/KOC (pH 5.5):
ACD/LogD (pH 7.4):
ACD/BCF (pH 7.4):
ACD/KOC (pH 7.4):
Polar Surface Area:
Polarizability:
Surface Tension:
Molar Volume:

Click to predict properties on the Chemicalize site

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Trazodone Hydrochloride C19H23Cl2N5O structure – Flashcards

Experimental Melting Point:

Experimental Solubility:

Safety:

Target Organs:

Drug Status:

Compound Source:

Bio Activity:

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