Quorum Sensing – Flashcards

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Quorum Sensing
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form of gene expression which is regulated in response to cell density. Used as form of communication between cells through autoinducers. Commonly found in biofilms.
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Signal Peptides
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molecules used for quorum sensing in Gram-positive bacteria
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AHLs
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molecules used for quorum sensing in Gram-negative bacteria
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Autoinducer
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a molecule which is produced by cells in a biofilm. When the signal molecule reaches appropriately high concentrations in a cell, it triggers the transcription of specific genes
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Biofilm
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consists of microbial colonies which are encased in an adhesive, usually made of a polysaccharide and attached to surfaces
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Persistor phenotype
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a state in which specialized cells are produced within a biofilm. These cells are not actively growing or dividing cells, they are not susceptible to antibiotics and are specialized survivor cells
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