Pharmacology 1 – Flashcards
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major ADE for thiazide is
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electrolyte and metabolic disturbances
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A decreasing response to the same amount of medication that requires progressively higher doses is called:
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Tolerance
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A dilute alcoholic extract that is commonly used a skin antiseptic is called:
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Tincture
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A liquid, usually water, that contains one or more chemical substances that are dissolved entirely is called:
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Solution
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A medication is called an antagonist if:
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It has a higher affinity for the receptor site than the chemical mediator
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A medication that possesses a negative chronotropic effect will:
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Cause a decrease in heart rate
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A medication that stimulates a response in a receptor site is said to be:
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An agonist
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A PT undergoing a kidney transplant would MOST likely be prescribed what?
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Immunosuppressant
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Semisolid preparation for external application to the body, usually containing a medical substance is called:
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An ointment
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Adrenergic nerve fibers release:
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Epi and norepi
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After ACh is synthesized and used by the body/
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AChE breaks the ACh down into choline and acetate
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All neuromuscular blocking agents:
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Affect the parasympathetic nervous system and induce paralysis
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An investigational new drug may enter clinical trials in humans only after:
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It has been tested on at least 2 animals
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ACE inhibitors reduce blood pressure by:
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Suppressing the conversion of angiotensin 1 to angiotensin 2
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Bioavailability is most accurately defined as
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The amount of medication that is still active when it reaches its target organ
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Compared to the maintenance dose of particular medication, a loading dose is:
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A larger dose, of the same concentration, and intended to achieve the therapeutic blood level quickly
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For a medication to carry the USP label:
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It's active ingredients must be within 95%-105% of that stated on the label
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Functionally, the nervous system is divided into the:
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Central and peripheral nervous system
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Interaction between medications that causes one medication to enhance the effects of the other is called
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Potentiation
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The Narcotic Control Act of 1956:
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Increased the penalties for violation of the Harrison Narcotic Act, made the possession of heroin illegal, outlawed the acquisition and transportation of marijuana
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The study of the metabolism and action of medications within the body with particular emphasis on absorption, duration of action, and method of excretion is called:
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Pharmacokinetics
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The systemic effect of a medication:
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Almost invariably involve more than one organ
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The term affinity, as it applies to pharmacology, is most accurately defined as:
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Attraction between a medication and it's receptor
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The time that it takes for the concentration of a medication to reach a minimum effective level at its target tissue is called:
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Onset of action
