Patho Unit 7 – Flashcards

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The clinical significance of BPH resides in its tendency to compress the ________ and cause partial/complete obstruction of urinary outflow, resulting in over-distention of the bladder.
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Urethra
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Testicular __________ is a twisting of the spermatic cord that suspends the testis.
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torsion
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Testicular torsion obstructs venos drainage, with resultant edema and hemorrhage and subsequent _______ obstruction. This is a medical emergency needing imediate attention.
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Arterial
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____________ cancer is the second most frequently diagnosed cancer in men, and the highest rates in the world are found in the United States.
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Prostate
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A weak urinary stream, postvoid dribbling, frequency of urination, and nocturia are classic symptoms of an enlarged prostate.
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True
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In regards to polycystic ovary syndrome, elevated _________ _________ results in increased androgen productio and contributes to a vicious cycle of anovulation and multiple cyst formation. (Please spell out)
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Luteinizing hormone
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Certain types of sexually transmitted human papillomaviruses are risk factors for a neoplasia, which can be a precursor lesion of invasive carcinoma.
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True
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Polycystic ovary syndrome is a common ___________ disorder.
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Endocrine
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Risk factors for ______ ______ include increasing age, family history and hormonal influences (late menopause).
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Breast cancer
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Ovarian cancer has severe early symptoms and is most often diagnosed in its early stages.
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False
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Symptoms that are believed to have a strong correlation to ______ _______ include increased abdominal size, dyspepsia, early satiety or bloating.
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Ovarian cancer
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________ therapy is used to block the effects of estrogen on the growth of breast cancer cells.
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Hormone
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________ represents an inflammation of the vagina that is characterized by vaginal discharge and burning, itching, redness and swelling of the vaginal tissues. Infections transmitted sexually are a common cause.
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Vaginitis
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Cancer of the breast is the most common cancer in females.
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True
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The incidence of _______ _______ is much lower in countries where women bear numerous children.
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Ovarian cancer
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_______ lubricates the hair and skin, preventing evaporation of moisture and helps conserve body heat.
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Sebum
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________ is an unpleasant sensation of itch leading to the desire to scratch.
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Puritius
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________ are small fluid-filled blisters (often seen with Herpes).
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Vesicles
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The ________ ______ are structures that become inflamed in acne.
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Sebaceous glands
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_____________, or the sensation of itch, is a symptom common to many skin disorders.
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pruritus
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Sebaceous glands, which release a lubricant for the skin and hair, are located over the entire skin surface except for the palms, soles, and sides of the feet.
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True
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Skin cancers affect light-skinned persons more commonly than dark-skinned persons.
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True
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Although ________ represents a small subset of skin cancers, it is the most deadly since it's a rapidly progressing, metastatic form of cancer.
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Melanoma
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_______-_______ full-thickness burns involve the entire epidermis and dermis.
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Second degree
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Varicella in adults is of similar significance and severity as in children.
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False
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Allergic and hypersensitivity ___________ involved the inflammatory response to multiple agents. The disorders are usually characterized by edema.
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Dermatoses
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The structure of the skin renders it susceptible to bacterial and fungal infections but resistant to viral infections.
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False
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_________ instability begins almost immediately with injury to capillaries in the burned area and surrounding tissue. Patients often present with hypovolemic shock in the ER.
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Hemodynamic
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This produces direct damage to the DNA and other nuclear proteins (in the skin) and produced free radicals: _______ radiation.
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Ultraviolet
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Moderate to severe cases of ____ may be managed with systemic antibiotics.
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Acne
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Dysplastic (pre-cancerous) _____ are usually larger than others. Their appearance is flat, slightly raised plaque with a pebbly surface.
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Nevi
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This disease is usually manifested by raised, well-demarcated, erythematous plaques with adherent silvery scales:_________. Histologically it is characterized by increased epidermal turnover with marked epidermal thickening.
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Psoriasis
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This common childhood disease is characterized by macules over various parts of the body, mild to extreme puritus and cold-like symptoms: _________.
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Varicella, Chickenpox
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Malignant melanoma, which is a malignant tumor of melanocytes, is a rapidly progressive and metastatic form of skin cancer.
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True
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PTH prevents serum calcium levels from falling below and serum ________ levels rising above normal physiologic concentrations.
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Phosphate
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The process of bone formation and mineral metabolism is complex and involves the interplay among the actions of PTH, ____________, and vitamin D.
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calcitonin
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The articulating areas of a joint are nourished indirectly by the ______ _____ rather than by blood vessels.
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Synovial fluid
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The tendons and ligaments of the joint capsule are sensitive to position and movement, particularly stretching and twisting. Their _________ function reflexively to adjust the tension of the muscles that support the joint.
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Proprioceptors
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Whereas PTH increases blood calcium levels, the hormone _______ lowers blood calcium levels.
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Calcitonin
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________ involves reabsorption of the excess bony callus that develops in the marrow space and encircles the fracture site.
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Remodeling
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_______________ represents an acute or chronic infection of the bone and is very difficult to treat and eradicate.
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Osteomyelitis
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_________ formation is thought to be necessary for the initiation of cellular events essential to bone healing.
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Hematoma
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______________ is an aggressive and highly malignant bone tumor with primary symptoms of deep localized pain with nighttime awakening and swelling in the affected bone.
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Osteosarcoma
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The treatment of bone tumors includes surgery in combination with multi-agent ________, both before and after surgery.
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Chemotherapy
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Legg-Calvé-Perthes disease is a childhood disorder that specifically involves the knee.
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False
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__________ is an aggressive and highly malignant tumor of the bone.
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Osteosarcoma
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All forms of scoliosis can be corrected with continued use of a brace.
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False
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____________ osteomylitis originates with infectious organisms that reach bone through the bloodstream.
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Hematogenous
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[X] __________ [Y] _______ fractures occur when normal stress is applied to bones that have been weakened by disease or tumors.
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Pathologic, stress
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[X]_____-[Y]_____-[Z]_____ disease is an ideopathic osteoneocrotic disease of the proximal femoral epiphysis with later reabsorption.
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Legg, Calve, Perthes
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Sclerosis, or formation of new bone and cysts, usually occurs at the joint margins, forming abnormal bony outgrowths called estophytes or spurs. This is charachteristic of _________.
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Osteoarthritis
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_________ of joints (crepitus) and joint locking may occur when the joint is moved.
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Cracking
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_______________ arthritis is a systemic inflammatory disease that attacks joints by producing a proliferative synovitis that leads to destruction of the articular cartilage and underlying bone.
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Rheumatoid
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The pathogenesis of ___________ ________ can be viewed as an aberrant immune response that leads to synovial inflammation and destruction of the joint architecture.
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Rheumatoid arthritis
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_______ is a condition that is common to all metabolic bone diseases.
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Osteopenia
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Regular exercise and adequate calcium and vitamin D intake are important factors in preventing ________. Calcitonin is also one of the drugs used in treatment.
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Osteoporosis
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Often, the first manifestations of the disorder are those that accompany a skeletal-fracture, a _________ compression or fracture of the hip, pelvis, humerus or other bones
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Vertebral
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_______________ is a skeletal disorder characterized by the loss of bone mass and deterioration of the architecture of cancellous bone with a subsequent increase in bone fragility and susceptibility to fractures.
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Osteoporosis
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Arthalgias and arthritis are among the most common occurring early symptoms of [X]_______ [Y]______ [Z]________. Renal involvement occurs in about half to two-thirds of persons as well.
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Systemic, Lupus, Erythematosus
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All persons affected with rheumatoid arthritis have the presence of the rheumatoid factor, an auto antibody that reacts with a fragment of immunoglobulin G to form immune complexes.
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False
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Systemic lupus erythematosus is a chronic inflammatory disease that can affect virtually any organ system, including the musculoskeletal system.
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True
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Rheumatic disorders have signs and symptoms that are limited to the skeletal system.
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False
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Premature __________ is increasingly being seen in female athletes owing to an increased prevalence of eating disorders and amenorrhea.
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Osteoporosis
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_______________ is a condition that is common to all metabolic bone diseases and is characterized by a reduction in bone mass greater than expected for age, race, or sex.
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Osteopenia
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