NU275 Kaplan Review – Flashcards
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            Anemia
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        A condition in which the blood doesn't have enough healthy red blood cells.
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            Signs & Symptoms of Anemia
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        dizziness, fatigue, lightheadedness, malaise, or weakness Tachycardia, palpitations brittle nails, headache, pallor, or shortness of breath
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            Treatment for Anemia
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        Treatment depends on the underlying diagnosis.  Iron supplements may be used for iron deficiency.  Vitamin B supplements maybe used for low vitamin levels.  Blood transfusions may be used for blood loss.  Medications to induce blood formation may be used if the body's blood production is reduced.
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            Atherosclerosis
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        The build-up of fats, cholesterol & other substances in and on the artery walls.
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            Signs & Symptoms of Atherosclerosis
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        Atherosclerosis often has no symptoms until a plaque ruptures or the buildup is severe enough to block blood flow.  People may experience: Pain the leg while exercising, erectile dysfunction, heart attack, mini-strokes (transient ischemic attacks), poor wound healing, or stroke
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            Treatment for Atherosclerosis
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        A healthy diet and exercise can help. Treatments include medications, procedures to open blocked arteries and surgery.  diet:  LESS fat, sugar, red meat  MORE fruit veggies, white meat, fish   Medications: Statin, Blood thinners, and Cholesterol medication  Medical procedure: Coronary stent  Angioplasty  Surgery Coronary artery bypass surgery  Carotid endarterectomy
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            Peripheral vascular disease
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        A circulatory condition in which narrowed blood vessels reduce blood flow to the limbs.
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            Symptoms of Peripheral Vascular Disease
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        Symptoms may include leg pain, particularly when walking.  People may experience: Pain areas in the buttocks, pain can occur in the leg and improved with rest or in the leg while exercising,  cool skin, loss of hair on the legs, thinning of skin on the legs, or ulcers
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            Treatment for Peripheral Vascular Disease
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        Self Care: Physical exercise, Quitting smoking, and Heart-Healthy diet  Medications: Statin, Vasodilator, and Blood thinners  Medical Procedure: Angioplasty
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            Liver Cancer (Hepatic Cancer)
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        Cancer that begins in the cells of the liver.
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            Symptoms of Liver Cancer
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        Symptoms are uncommon in the early stages of liver cancer.   Later, symptoms may include weight loss, belly pain, bloating, fluid in abdomen, nausea, vomiting, & yellowed skin and eyes. Also cancer-related fatigue, loss of appetite, itching.
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            Treatment for Liver Cancer
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        Medications: Chemotherapy   Medical procedure Cryoablation, Percutaneous ethanol injection, Embolization, Transarterial chemoembolization, Sir-Spheres, and Radiofrequency ablation  Surgery: Liver transplantation  Hepatectomy
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            Cardiomyopathy
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        An acquired or hereditary disease of the heart muscle.
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            Signs & Symptoms of Cardiomyopathy
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        Symptoms include breathlessness, swollen legs and feet, and a bloated belly.  Also: Pain in the chest, dizziness, fatigue, or loss of appetite, abnormal heart rhythm, tachycardia, or murmur, bloating or fluid in the abdomen. Also common: coughing, shortness of breath, swelling in extremities, or weight gain
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            Treatment for Cardiomyopathy
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        Treatment consists of ace inhibitors and diuretics,drugs, implanted devices, surgery, and in severe cases, a transplant  Medications: Blood thinners, Beta blocker, ACE inhibitor, Diuretic, Antihypertensive drug, Statin, and Antiarrhythmic agent  Medical Procedure: Cardiac catheterization and Revascularization  Surgery: Coronary artery bypass surgery and Heart transplant  Devices: Pacemaker and Implantable cardioverter-defibrillator
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            Goiter
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        Abnormal enlargement of thyroid
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            Signs and Symptoms of Goiter
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        Lump or swelling in neck, and cough. Rarely, throat tightness or trouble breathing, coughing, tachycardia, heat intolerance, shortness of breath, underactive thyroid, or weight gain
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            Treatment for Goiter
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        A small goiter that doesn't cause symptoms may not need treatment. Sometimes, medication or surgery.  Medication:  Antithyroid agent  Hormone therapy  Medical Procedure: Radioactive iodine therapy  Surgery: Thyroid removal Partial thyroidectomy
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            Embolic stroke
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        A blockage of blood supply to part of the brain caused by a clot or debris (embolus).
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            Symptoms of Embolic Stroke
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        Symptoms include trouble walking, speaking, and understanding. Paralysis or numbness of the face, arm, or leg also may occur.  People may experience:  Muscular: weakness, problems with coordination, stiff muscles, weakness of one side of the body, or paralysis of one side of the body  Cognitive: altered LOC, inability to recognize half of one's visual field (hemispatial neglect), inability to speak or understand, or mental confusion  Visual: blurred vision, sudden visual loss, temporary loss of vision in one eye, or vision disorder  Whole body: dizziness, fainting, or feeling faint  Sensory: leg numbness, pins and needles, or reduced sensation of touch  Speech: difficulty speaking, slurred speech, or impaired voice  Facial: muscle weakness or numbness  Also common: difficulty swallowing, limping, nausea, sleepiness, unsteadiness, weakness of limb, or difficulty raising the foot
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            Treatment for Embolic Stroke
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        Treatment consists of blood thinners and clot busting medications Emergency treatment includes medications or a procedure to break up clots.  Medications: Tissue plasminogen activator, Blood thinners, and Antihypertensive drug  Surgery: Embolectomy  Therapies: Stroke rehabilitation  Medical Procedure: Left atrial appendage occlusion  Supportive Care:  IV fluids
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            Subarachnoid hemorrhage (SAH)
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        Bleeding in the space between the brain and the tissue covering the brain.
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            Signs & Symptoms of Subarachnoid hemorrhage
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        The main symptom is a sudden, severe headache.  People may experience: double vision, sensitivity to light, or vision loss, nausea or vomiting, abnormal heart rhythm, altered LOC, coma, fainting, seizures, stiff neck, or weakness of one side of the body
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            Treatment for Subarachnoid hemorrhage
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        Treatment depends on severity Hospital care is needed for supportive care and to stop bleeding and limit brain damage. Treatment may include surgery or catheter-based therapy.  Medical Procedure: Endovascular coiling and Clipping  Medications: Antihypertensive drug, Diuretic, and Anticonvulsant  Surgery: Ventriculostomy and Craniotomy  Supportive Care: Iv Fluids
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            Parkinson's disease
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        A disorder of the central nervous system that affects movement, often including tremors.
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            Signs and Symptoms of Parkinson's disease
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        Parkinson's often starts with a tremor in one hand. Other symptoms are slow movement, stiffness, and loss of balance. People may experience: Tremor: can occur at rest, in the hands, limbs, or can be postural  Muscular: stiff muscles, difficulty standing, difficulty with bodily movements, involuntary movements, muscle rigidity, problems with coordination, rhythmic muscle contractions, slow bodily movement, or slow shuffling gait Sleep: early awakening, nightmares, restless sleep, or sleep disturbances Whole body: fatigue, dizziness, poor balance, or restlessness Cognitive: amnesia, confusion in the evening hours, dementia, or difficulty thinking and understanding Speech: impaired voice, soft speech, or voice box spasms Mood: anxiety or apathy Nasal: distorted sense of smell or loss of smell Urinary: dribbling of urine or leaking of urine Facial: jaw stiffness or reduced facial expression Also common: blank stare, constipation, daytime sleepiness, depression, difficulty swallowing, drooling, falling, fear of falling, limping, loss in contrast sensitivity, neck tightness, small handwriting, trembling, unintentional writhing, or weight loss
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            Treatment for Parkinson's disease
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        Treatment consists of medications to increase dopamine  Medications: Dopamine promoter, Antidepressant, Cognition-enhancing medication, and Anti-Tremor  Selfcare: Physical Exercise
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            Spinal cord injury
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        Damage to any part of the spinal cord or nerves at the end of the spinal canal.
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            Signs and Symptoms of Spinal cord injury
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        A spinal cord injury often causes permanent loss of strength, sensation, and function below the site of the injury. People may experience: Muscular: muscle weakness, problems with coordination, stiff muscles, muscle spasms, or overactive reflexes Whole body: feeling faint or sweating Sensory: reduced sensation of touch or pins and needles Urinary: leaking of urine or urinary retention Also common: abnormal and painful sensation, leaking of stool, or shortness of breath
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            Treatment for Spinal cord injury
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        Treatment depends on severity Rehabilitation and assistive devices allow many people with spinal cord injuries to lead productive, independent lives. Treatments include drugs to reduce symptoms and surgery to stabilize the spine.  Supportive care Mouth-To-Mouth resuscitation  Medications Steroid, Blood pressure support, and Muscle relaxant  Surgery: Spinal Surgery  Therapies Rehabilitation and Hydrotherapy  Medical procedure Urinary catheterization and Traction
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            Multiple Sclerosis (MS)
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        A disease in which the immune system eats away at the protective covering of nerves.
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            Signs and Symptoms of Multiple Sclerosis
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        Multiple sclerosis causes many different symptoms, including vision loss, pain, fatigue, and impaired coordination. Pain areas: in the back or eyes Pain circumstances: can occur in the back due to head nod or with eye movement Tremor: can occur during precise movements, in the hands, or limbs Muscular: cramping, inability to rapidly change motions, involuntary movements, muscle paralysis, muscle rigidity, muscle weakness, problems with coordination, stiff muscles, clumsiness, muscle spasms, or overactive reflexes Whole body: fatigue, dizziness, heat intolerance, poor balance, vertigo, or weakness Sensory: pins and needles, abnormality of taste, reduced sensation of touch, or uncomfortable tingling and burning Urinary: excessive urination at night, leaking of urine, persistent urge to urinate, or urinary retention Visual: blurred vision, double vision, or vision loss Sexual: erectile dysfunction or sexual dysfunction Mood: anxiety or mood swings Speech: slurred speech or impaired voice Also common: constipation, depression, difficulty swallowing, difficulty thinking and understanding, flare, headache, heavy legs, limping, numbness of face, rapid involuntary eye movement, sleep deprivation, tongue numbness, or difficulty raising the foot
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            Treatment for Multiple Sclerosis
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        Treatment consists of immunosuppressants Physical therapy and medications that suppress the immune system can help with symptoms and slow disease progression.  Medications Immunosuppressive drug and Steroid  Therapies Counseling, Support group, Physical therapy, and Acupuncture  Selfcare Physical exercise
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            Sleep apnea
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        A potentially serious sleep disorder in which breathing repeatedly stops and starts.
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            Signs and Symptoms for Sleep apnea
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        Symptoms include snoring loudly and feeling tired even after a full night's sleep. People may experience:  Excessive daytime sleepiness, insomnia, nightmares, sleep deprivation, , episodes of no breathing, breathing through the mouth, or loud breathing, depression, dry mouth, dry throat, fatigue, headache, irritability, mood swings, or weight gain
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            Treatment for Sleep apnea
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        Treatment consists of weight loss exercise, and the use of a breathing assistance device at night, such as a continuous positive airway pressure (CPAP) machine & air way management. If needed surgery, tonsillectomy, Adenoid removal, and Palatoplasty.
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            Asthma (bronchial asthma)
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        A condition in which a person's airways become inflamed, narrow and swell, and produce extra mucus, which makes it difficult to breathe.
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            Signs and Symptoms of Asthma
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        Difficulty breathing, chest pain, cough, and wheezing. The symptoms may sometimes flare-up. People may experience: Cough: can occur at night, during exercise, can be chronic, dry, with phlegm, mild, or severe Respiratory: difficulty breathing, wheezing, breathing through the mouth, fast breathing, frequent respiratory infections, rapid breathing, or shortness of breath at night Also common: chest tightness, flare, anxiety, early awakening, fast heart rate, or throat irritation
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            Treatment for Asthma
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        Treatment consists of self care and bronchodilators Asthma can usually be managed with rescue inhalers to treat symptoms (albuterol) and controller inhalers that prevent symptoms (steroids). Severe cases may require longer-acting inhalers that keep the airways open (formoterol, salmeterol, tiotropium), as well as oral steroids.  Medications:  Bronchodilator, Steroid, and Anti-Inflammatory  Self Care Quitting Smoking  Supportive care Oxygen therapy
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            Tuberculosis
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        Tuberculosis (TB) Infection caused by Mycobacterium tuberculosis. Acid fast bacillus. Infectious disease Highly contagious Immunocompromised-HIV
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            Signs and symptoms & treatment of tuberculosis
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        Clinical manifestations: Dyspnea, chest pain, hemoptysis  Treatment: Long term antibiotics
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            Rheumatoid Arthritis:
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        Inflammatory joint disease Autoimmune destruction to synovial membrane and joints Systemic disease that affects the heart, lungs, kidneys, skin, as well as the joints
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            CM Of Rheumatoid Arthritis
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        Symmetric joint swelling, joint deformities  Rheumatoid nodules in organs Caplan syndrome Autoantibodies RF  Significantly more specific serum marker, anticitrullinated protein antibody (ACPA) Present for years to decades before synovial or radiographic changes become apparent Evaluation (four or more of the following) Morning joint stiffness lasting at least 1 hour Arthritis of three or more joint areas  Arthritis of the hand joints  Symmetric arthritis  Rheumatoid nodules  Abnormal amounts of serum RF  Radiographic changes
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            Treatment for Rheumatoid Arthritis
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        ¥ Disease-modifying antirheumatic drugs (DMARDs) such as methotrexate (MTX, first line), azathioprine, sulfasalazine, hydroxychloroquine, leflunomide, and cyclosporine ¥ Biological DMARDs (bDMARDs): Medications affect specific processes in the development of RA: Tumor necrosis factor inhibitors ¥ Monoclonal antibodies ¥ Education ¥ Nonsteroidal antiinflammatory drugs (NSAIDs), glucocorticoids, intraarticular steroid injections ¥ Physical and occupational therapy with therapeutic exercise and use of assistive devices ¥ Surgery: Synovectomy or joint replacement
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            HIV/AIDS (Also called: human immunodeficiency virus, acquired immunodeficiency syndrome)
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        HIV causes AIDS and interferes with the body's ability to fight infections.
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            Signs and Symptoms of AIDS
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        Within a few weeks of HIV infection, flu-like symptoms such as fever, sore throat, and fatigue can occur. Then the disease is usually asymptomatic until it progresses to AIDS. AIDS symptoms include weight loss, fever or night sweats, fatigue, and recurrent infections. People may experience: Pain areas: in the abdomen Pain can occur while swallowing Cough: can be dry Whole body: fatigue, fever, loss of appetite, malaise, night sweats, or sweating Gastrointestinal: nausea, persistent diarrhea, vomiting, or watery diarrhea Mouth: ulcers or white tongue Groin: sores or swelling Throat: difficulty swallowing or soreness Also common: opportunistic infection, headache, oral thrush, pneumonia, red blotches, severe unintentional weight loss, skin rash, or swollen lymph nodes
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            Treatment for AIDS
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        Treatment consists of Medications: HIV antiviral and Enzyme replacement therapy  No cure exists for AIDS, but strict adherence to anti-retroviral regimens (ARVs) can dramatically slow the disease's progress as well as prevent secondary infections and complications.
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            Chronic renal (kidney) failure (CKD)
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        Longstanding disease of the kidneys leading to renal failure.
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            Signs and Symptoms of Chronic renal failure
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        Symptoms develop slowly and aren't specific to the disease. Some people have no symptoms at all and are diagnosed by a lab test. Whole body: fatigue, high blood pressure, loss of appetite, malaise, or water-electrolyte imbalance Also common: kidney damage, abnormal heart rhythm, failure to thrive, fluid in the lungs, insufficient urine production, itching, kidney failure, severe unintentional weight loss, or swelling
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            Treatment for Chronic renal failure
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        Treatment depends on severity Medications help manage symptoms. In later stages, filtering the blood with a machine (dialysis) or a transplant may be needed.  Medical Procedure: Peritoneal dialysis, Hemofiltration, and Dialysis  Self Care Low Protein Diet  Medications Vitamin, Calcium reducer, Bone marrow stimulant, Diuretic, and Dietary supplement  Surgery: Kidney Transplantation
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            Renal calculi (Kidney Stones, Also called: nephrolithiasis)
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        A small, hard deposit that forms in the kidneys and is often painful when passed.
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            Signs and Symptoms of Renal calculi
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        The most common symptom is severe pain, usually in the side of the abdomen, that's often associated with nausea.  Pain areas: in the back or side part of the body Pain types: can be severe or sharp Pain circumstances: can occur during urination Gastrointestinal: nausea or vomiting Urinary: blood in urine or frequent urination Also common: acute abdomen or sweating
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            Treatment for Renal Calculi
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        Treatment consists of fluids and urinary retention medications Treatment includes pain relievers and drinking lots of water to help pass the stone. Medical procedures may be needed to remove or break up larger stones.  Supportive care Monitoring for changes or improvement, IV fluids, and Increase fluid intake  Medications Urinary retention medication, Narcotic, Nonsteroidal anti-Inflammatory drug, and Diuretic  Medical procedure Extracorporeal shockwave therapy, Ureteroscopic stone removal, and Laser lithotripsy
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            Acute Renal (Kidney) Failure (ARF)
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        A condition in which the kidneys suddenly can't filter waste from the blood.
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            Signs and Symptoms of Acute Renal (Kidney) Failure (ARF)
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        Decreased urinary output, swelling due to fluid retention, nausea, fatigue, and shortness of breath. Sometimes symptoms may be subtle or may not appear at all. Also: water-electrolyte imbalance, insufficient urine production or urinary retention, too much acid in blood and tissues
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            Treatment for Acute Renal (Kidney) Failure (ARF)
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        Treatment varies to addressing the underlying cause, treatments include fluids, medication, and dialysis.  Medications Diuretic  Medical procedure Dialysis  Devices Ureteral stent  Supportive care Fluid replacement
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            Urinary tract infection (UTI, bladder infection)
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        Inflammation of the urinary epithelium after invasion and colonization by some pathogen in the urinary tract  Retrograde movement of bacteria into the urethra and bladder  Classification:  Location or complicating factors  Complicated UTI versus uncomplicated UTI  Cystitis: Bladder inflammation  Pyelonephritis: Inflammation of upper urinary tract  Most common pathogens Escherichia coli Staphylococcus saprophyticus
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            UTI Evaluation & Treatment
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        Evaluation: Urine Culture, UA Treatment: Antimicrobial therapy
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            Osteoporosis
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        Porous bone Poorly mineralized bone Primary versus secondary Bone density
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            Potential causes for Osteoporosis
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        Decreased levels of estrogen and testosterone Decreased activity level Inadequate levels of vitamins D and calcium or magnesium Alterations in the osteoprotegerin (OPG), receptor activator of nuclear factor kappa B (κB) ligand (RANKL), and receptor activator of nuclear factor κB (RANK): OPG/RANKL/RANK system Postmenopausal osteoporosis Increased osteoclast activity, changes in OPG, insulin-like growth factor (IGF), and family history Glucocorticoids Increase RANKL expression and inhibit OPG production by osteoblasts, leading to lower bone density
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            Clinical manifestations for osteoporosis
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        Pain, bone deformity, fractures, kyphosis (hunchback), and diminished height
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            Prevention & treatment for osteoporosis
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        Prevention: Regular moderate weight-bearing exercises Calcium intake sufficient to maintain normal calcium balance during adolescence Sufficient intake of magnesium  Treatment:  Estrogen Bisphosphonates, denosumab, teriparatide, parathyroid hormone (PTH) 1-84
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            Pleural Effusion
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        Presence of fluid in the pleural space.   Treatment: Chest tube
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            Diabetes Mellitus
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        Is a dysfunction of the endocrine pancreas. Affects metabolism of fat, protein, and carbohydrates. Is characterized by hyperglycemia, resulting from defects in insulin secretion, insulin action, or both. Categories: Type 1 Type 2 Other specific types Gestational diabetes
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            Somogyi Effect
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        Hypoglycemia with rebound hyperglycemia Counterregulatory hormones cause gluconeogenesis Most common in people with type 1 diabetes mellitus and children
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            Cirrhosis
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        Inflammtory disorder of the liver The most common cause of ascites. Fibrotic scarring of the liver occurs in response to inflammation and tissue damage. Chronic liver diseases in children can progress to cirrhosis, although infrequently. Complications for cirrhosis in children are the same as those in adults. Children may also experience growth failure, nutritional deficits, and developmental delays.
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            Intestinal Obstruction
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        Check book table36-2, pg 913.   Common causes of intestinal obstruction:  Herniation, Intussusception, volvulus, diverticulosis, tumor, paralytic ileus, adhesions.
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            Systemic lupus erythematosus (SLE)
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        An inflammatory disease caused when the immune system attacks its own tissues.
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            Symptoms of SLE
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        Fatigue, joint pain, rash, and fever.
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            Treatment for SLE
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        Treatment consists of immunosuppressants While there's no cure for lupus, current treatments focus on improving quality of life through controlling symptoms and minimizing flare-ups. This begins with lifestyle modifications, including sun protection and diet. Further disease management includes medications, such as anti-inflammatories and steroids.
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            Glomerulonephritis
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        inflammation of the tiny filters in your kidneys
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            Symptoms of Glomerulonephritis
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        Pink or cola-colored urine from red blood cells in your urine (hematuria) Foamy urine due to excess protein (proteinuria) High blood pressure (hypertension) Fluid retention (edema) with swelling evident in your face, hands, feet and abdomen
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            Treatment for glomerulonephritis
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        Treatment depends on acute or chronic form of the disease, The underlying cause, The type and severity of your signs and symptoms Some cases of acute glomerulonephritis, especially those that follow a strep infection, might improve on their own and require no treatment. If there's an underlying cause, such as high blood pressure, an infection or an autoimmune disease, treatment will be directed to the underlying cause.  the goal of treatment is to protect your kidneys from further damage.
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            Nephrotic Syndrome
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        A kidney disorder that causes the body to excrete too much protein in the urine.
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            Signs and symptoms of Nephrotic Syndrome
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        Symptoms include swelling around the eyes and in the feet and ankles, foamy urine, and weight gain due to excess fluid retention.
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            Treatment for Nephrotic Syndrome
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        Treatment consists of steroids and immunosuppressants Treatment addresses underlying conditions and might include blood pressure medications and water pills.  Self-care low sodium diet   Medications: Diuretic, ACE inhibitor, Antihypertensive drug, Statin, Steroid, and Immunosuppressive drug
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            Hodgkin Lymphoma
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        Cancer of the part of the immune system called the lymphatic system.
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            Signs & Symptoms of Hodgkin Lymphoma
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        Lymph nodes in the neck, armpits, or groin may swell. Fatigue, fever, and chills , loss of appetite, shortness of breath, or weight loss
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            Treatment for Hodgkin Lymphoma
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        Chemotherapy, radiation, and in rare cases stem-cell transplant.
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            Mononucleosis (infectious Mononucleosis)
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        Often called mono or kissing disease, an infection with the Epstein-Barr virus.
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            Signs & symptoms of Mononucleosis
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        Fatigue, fever, rash, and swollen glands. The elderly may not have typical symptoms.   Pain while swallowing, chills, or malaise, sore throat, swollen lymph nodes, swollen tonsils, body ache, headache, or nausea
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            Treatment for Mononucleosis
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        Treatment involves rest, fluid replacement, and over-the-counter pain and fever-reducing medicines to ease symptoms.
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            Non-Hodgkin lymphoma (NHL)
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        Cancer that starts in the lymphatic system.
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            Signs and Symptoms of NHL
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        Symptoms include swollen lymph nodes, fever, belly pain, or chest pain., anemia, fatigue, loss of appetite, or night sweats, or weight loss
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            Treatment for NHL
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        Treatments may include chemotherapy, radiation therapy, stem-cell transplant, or medications (bone marrow stimulant, steroids)
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            Multiple myeloma (Kahler's disease)
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        Cancer of plasma cells
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            Symptoms of Multiple myeloma
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        Symptoms may not be present or may be non-specific, such as loss of appetite, bone pain, and fever.  People may experience: Pain areas: in the back or bones Whole body: anemia, fatigue,  Also common: constipation, hypercalcemia, kidney damage, or weight loss
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            Treatment for Multiple myeloma
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        Treatments include medications, chemotherapy, corticosteroids, radiation, or a stem-cell transplant.  Medications: Chemotherapy, Blood transfusion, Steroid, and Bone health  Surgery: Autotransplantation
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            Pancreatic Cancer
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        Cancer that begins in the organ lying behind the lower part of the stomach (pancreas).
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            Symptoms of Pancreatic Cancer
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        There are no symptoms in the early stages. Later stages are associated with symptoms.   Pain areas: in the abdomen or middle back Gastrointestinal: fluid in the abdomen or nausea Whole body: fatigue or loss of appetite Also common: dark urine, weight loss, or yellow skin and eyes
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            Treatment for Pancreatic Cancer
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        Treatment may include surgically removing the pancreas, radiation, and chemotherapy.
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            Chemotaxis

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        During chemotaxis, cells move in response to chemical signals. The action of neutrophils is just one example of how the body uses chemotaxis to respond to an infection.   Aside from the cells that are already in position in the tissues (such as the fixed tissue macrophages and mast cells), neutrophils are the first responders to inflammation.
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            Lung Cancer
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        A cancer that begins in the lungs and most often in people who smoke.
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            Signs and Symptoms of Lung Cancer
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        Symptoms include cough (often with blood), chest pain, wheezing, and weight loss. These symptoms often don't appear until the cancer is advanced.  People may experience: Pain areas: in the chest or rib Cough: can be chronic, dry, with phlegm, or with blood Whole body: fatigue, loss of appetite, or weakness Respiratory: frequent respiratory infections, shortness of breath, or wheezing Also common: hoarseness, swollen lymph nodes, or weight loss
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            Treatment for Lung Cancer
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        Treatments vary but may include surgery, chemotherapy, radiation therapy, targeted drug therapy, and immunotherapy.  Self Care: quitting smoking  Medications: chemotherapy  Surgery: Pulmonary lobectomy, Wedge resection, and Video-Assisted thoracoscopic surgery  Medical Procedure: Thoracotomy and Radiation therapy
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            Edema
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        Swelling caused by excess fluid trapped in your body's tissues. Most commonly noticed in the hands, arms, feet, ankles and legs.  Edema can be the result of medication, pregnancy or an underlying disease — often heart failure, kidney disease or cirrhosis of the liver.  Taking medication to remove excess fluid and reducing the amount of salt in your food often relieves edema. When edema is a sign of an underlying disease, the disease itself requires separate treatment.
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            Signs and Symptoms of Edema
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        Swelling or puffiness of the tissue directly under your skin Stretched or shiny skin Skin that retains a dimple after being pressed for several seconds Increased abdominal size When to see a doctor  May Experience: Shortness of breath Difficulty breathing Chest pain
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            Edema Tets & Diagnosis
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        To understand what might be causing your edema, your doctor will perform a physical exam and ask you questions about your medical history. This information is often enough to determine the underlying cause of your edema. In some cases, X-rays, ultrasound exams, blood tests or urine analysis may be necessary.
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            Metaplasia
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        A change of cells to a form that does not normally occur in the tissue in which it is found.
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            Neuropathic Pain (Nerve Pain)
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        Type of chronic pain that occurs when nerves in the central nervous system become injured or damaged. Can erode quality of life.
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            Signs & Symptoms and Treatment for Neuropathic Pain
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        Patients may describe their symptoms as sharp, dull, hot, cold, sensitive, itchy, deep, stinging, burning, or some other descriptor. Additionally, some patients may feel pain with a light touch or pressure.  Medications: anti-seizure & anti-depressants
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            Hypoxia (Hypoxemia)
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        Lack of oxygen reaching the tissues.
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            Signs & Symptoms of Hypoxia
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        Acute: shortness of breath rapid breathing Tachycardia  Other:  Wheezing Sweating Coughing
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            Treatment for Hypoxia
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        Give additional oxygen to the patient and into the body (blood) as quickly as possible   Nasal Cannula Oxygen Masks Hyperbaric chamber
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            Pathologic Fracture: Hip Fracture
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        A serious injury, with complications that can be life-threatening. The risk of hip fracture rises with age.  Older people are at a higher risk of hip fracture because bones tend to weaken with age (osteoporosis). Multiple medications, poor vision and balance problems also make older people more likely to trip and fall (one of the most common causes of hip fracture.)
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            Signs & Symptoms of Hip Fracture
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        Inability to move immediately after a fall Severe pain in your hip or groin Inability to put weight on your leg on the side of your injured hip Stiffness, bruising and swelling in and around your hip area Shorter leg on the side of your injured hip Turning outward of your leg on the side of your injured hip
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            Treatment for hip fracture
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        Involves a combination of surgery, rehabilitation and medication  Surgery: Internal repair using screws Partial hip replacement Total hip replacement.
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            Carcinoma in situ (CIS)

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        A group of abnormal cells that are found only in the place where they first formed in the body (see left panel). These abnormal cells may become cancer and spread to nearby normal tissue (see right panel).
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            Epidural Hematoma
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        An epidural hematoma (EDH) is bleeding between the inside of the skull and the outer covering of the brain (called the dura).  Often caused by a skull fracture during childhood or adolescence. This type of bleeding is more common in young people because the membrane covering the brain is not as closely attached to the skull as it is in older people and children younger than 2 years.
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            Signs and Symptoms of Epidural Hematoma
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        LOC Confusion Dizziness Drowsiness or altered level of alertness Enlarged pupil in one eye Headache (severe) Head injury or trauma followed by loss of consciousness, a period of alertness, then rapid deterioration back to unconsciousness Nausea or vomiting Weakness in part of the body, usually on the opposite side from the side with the enlarged pupil
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            Treatment for Epidural Hematoma
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        An EDH is an emergency condition. Treatment goals include:  Taking measures to save the person's life Controlling symptoms Minimizing or preventing permanent damage to the brain
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            Cell Injury
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        It is change in cell's morphology and function in response to stress. Occurs when the limits to an adaptive response (adaptation) have been exceeded or if the cells are not able to adapt
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            Causes Of Cell Injury
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        1- Oxygen deprivation (hypoxia, ischemia) 2- Oxygen free radicals. 3- Physical agents (heat, cold, radiation, trauma). 4- Chemical agents e.g. drugs, toxins 5- Infectious organisms. 6- Immunologic reactions. 7- Genetic derangements. 8- Nutritional imbalances e.g. starvation, obesity
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            Immune Function in the Elderly
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        As you grow older, your immune system does not work as well. The following immune system changes may occur:  The immune system becomes slower to respond. This increases your risk of getting sick. Flu shots or other vaccines may not work as well or protect you for as long as expected. An autoimmune disorder may develop. This is a disease in which the immune system mistakenly attacks and destroys healthy body tissues. Your body may heal more slowly. There are fewer immune cells in the body to bring about healing. The immune system's ability to detect and correct cell defects also declines. This can result in an increased risk of cancer.
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            To decrease the risks from immune system aging:
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        Get the flu and pneumonia vaccines, and any other vaccines your health care provider recommends. Get plenty of exercise. Exercise helps boost your immune system. Eat healthy foods. Good nutrition keeps your immune system strong. DO NOT smoke. Smoking weakens your immune system. Limit your intake of alcohol. Ask your provider how much alcohol is safe for you. Look into safety measures to prevent falls and injuries. A weak immune system can slow healing.
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            Allergic Reaction
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        Occur when your immune system reacts to a foreign substance — such as pollen, bee venom or pet dander — or to a food that doesn't cause a reaction in most people.  Your immune system produces substances known as antibodies. When you have allergies, your immune system makes antibodies that identify a particular allergen as harmful, even though it isn't. When you come into contact with the allergen, your immune system's reaction can inflame your skin, sinuses, airways or digestive system.
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            Signs & Symptoms of Allergies
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        Depends on person & type of allergy:  Sneezing Itching of the nose, eyes or roof of the mouth Runny, stuffy nose Watery, red or swollen eyes (conjunctivitis) Tingling mouth Swelling of the lips, tongue, face or throat Hives Anaphylaxis A large area of swelling (edema) at the sting site Cough, chest tightness, wheezing or shortness of breath Itchy skin Rash Facial swelling Redden Flake or peel Loss of consciousness A drop in blood pressure Severe shortness of breath Skin rash Lightheadedness A rapid, weak pulse Nausea and vomiting
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            Treatment for Allergies
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        Allergen avoidance.  Medications. Immunotherapy.  Sublingual drugs are used to treat some pollen allergies. Emergency epinephrine.