Lecture 34 – Flashcards
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| gag |
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| gene that encodes structural proteins of retrovirus |
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| pol |
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| encodes reverse transcriptase and integrase in retrovirus |
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| env |
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| encode envelope proteins of retrovirus |
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| provirus |
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| virus genome that is integrated into host chromosome |
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| defective viruses |
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| clearly derived from viruses but have become dependent upon other viruses to supply certain gene products |
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| helper viruses |
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| virus that provides functions to help a defective virus |
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| satellite viruses |
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| a type of defective virus that has no intact close relative so they use unrelated viruses as helpers |
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| viroids |
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| infectious RNA molecules that differ from viruses by lacking a capsid |
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| prions |
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| distinct extracellular form consisting solely of protein, no nuclide acid |
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| transmissible spongiform encephalopathies (TSEs) ex: scrapie, mad cow, kuru, etc. |
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| prion diseases in animals and humans |
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| PrP^C |
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| prion protein found in healthy individuals, native form |
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| PrP^Sc |
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| pathogenic form of prion protein |
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| infectious, sporadic, or inherited |
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| how prions occur |
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| Prnp |
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| gene that codes for prion protein |
