Infectious Disease Study Guide Final

mecA
Penicillin resistant gene found in Stap. Aureus and Strep. pneumo
erm
(erythromycin ribosomal methylase)
Erythromycin (macrolide) Resistance
Mainly in Strep. pneumo
mef
(macrolide efflux pump)
Macrolide resistance
S. pyogenes and S. pneumoniae
bla-kpc
carbapenemase enzyme
Enterobacteriaceae
(Mainly Klebsiella pneumoniae)
Dtest (ICR)
Method to detect inducible clindamycin resistance in coagulase negative staphylococci
van A
Vancomycin-resistant Enterococcus
(Van-A causes resistance to both vancomycin and teicoplanin)
Therapy for ampC (β-lactamase) producing pathogens
Therapy for ESBL producing pathogens
Carbapenems
Tigecycline
Possibly Pip/Taz
Therapy for carbapenemase producing pathogens
Polymixons
Tigecycline
alpha hemolytic patterns on blood agar
Partial hemolysis (green color)
Strep. Pneumoniae or
Strep. Viridans
beta hemolytic patterns on blood agar
Complete hemolysis (clear)
Strep. Pyogenes
or Group B Strep.
gamma hemolytic patterns on blood agar
No hemolysis (red color)
Enterococcus spp
Pneumovax vs Prevnar
Prevnar = pneumococcal conjugate vaccine (7 or 13 serotype coverage)
Pneumovax = pneumococcal polysaccharide vaccine (23 serotype coverage)
DPT letters definition
DPT primary vaccination in children vs booster in adults
CSF LP
nucleoside
nucleotide
Pen G vs procaine penG vs benzathine pen G
linezolid side effects
thrombocytopenia, bone marrow suppression after 2 wks of therapy, peripheral neuropathy, serotonin syndrome
Desensitization definition & where it comes into play
If patient w/ neuro syphilis has penicillin allergy give small doses and build up to desensitize and treat infection