Infectious Disease Study Guide Final

mecA
Penicillin resistant gene found in Stap. Aureus and Strep. pneumo

erm
(erythromycin ribosomal methylase)
Erythromycin (macrolide) Resistance
Mainly in Strep. pneumo

mef
(macrolide efflux pump)
Macrolide resistance
S. pyogenes and S. pneumoniae

bla-kpc
carbapenemase enzyme
Enterobacteriaceae
(Mainly Klebsiella pneumoniae)

Dtest (ICR)
Method to detect inducible clindamycin resistance in coagulase negative staphylococci

van A
Vancomycin-resistant Enterococcus
(Van-A causes resistance to both vancomycin and teicoplanin)

Therapy for ampC (β-lactamase) producing pathogens

Therapy for ESBL producing pathogens
Carbapenems
Tigecycline
Possibly Pip/Taz

Therapy for carbapenemase producing pathogens
Polymixons
Tigecycline

alpha hemolytic patterns on blood agar
Partial hemolysis (green color)
Strep. Pneumoniae or
Strep. Viridans

beta hemolytic patterns on blood agar
Complete hemolysis (clear)
Strep. Pyogenes
or Group B Strep.

gamma hemolytic patterns on blood agar
No hemolysis (red color)
Enterococcus spp

Pneumovax vs Prevnar
Prevnar = pneumococcal conjugate vaccine (7 or 13 serotype coverage)
Pneumovax = pneumococcal polysaccharide vaccine (23 serotype coverage)

DPT letters definition

DPT primary vaccination in children vs booster in adults

CSF LP

nucleoside

nucleotide

Pen G vs procaine penG vs benzathine pen G

linezolid side effects
thrombocytopenia, bone marrow suppression after 2 wks of therapy, peripheral neuropathy, serotonin syndrome

Desensitization definition & where it comes into play
If patient w/ neuro syphilis has penicillin allergy give small doses and build up to desensitize and treat infection

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