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HYDRALAZINE HYDROCHLORIDE C8H9ClN4 structure – Flashcards

Flashcard maker : Darren Farr

Contents

Experimental Melting Point:
Experimental Flash Point:
Experimental Gravity:
Experimental Solubility:
Safety:
Target Organs:
Compound Source:
Bio Activity:

Molecular Formula	C₈H₉ClN₄
Average mass	196.637 Da
Density
Boiling Point
Flash Point
Molar Refractivity
Polarizability
Surface Tension
Molar Volume

Experimental data
Predicted – ACD/Labs
Predicted – ChemAxon
Predicted – Mcule

Experimental Physico-chemical Properties
- Experimental Melting Point:
  
  275 °C (Decomposes) Alfa Aesar
  
  275 °C (Decomposes) Alfa Aesar B22995
  
  274 °C Biosynth Q-201208
  
  273 °C LabNetwork LN00196621
- Experimental Flash Point:
  
  251.3 °C Biosynth Q-201208
- Experimental Gravity:
  
  251.3 g/mL Biosynth Q-201208
- Experimental Solubility:
  
  10 mM in DMSO MedChem Express HY-B0464
  
  DMSO <1 mg/mL; Water 1 mg/mL MedChem Express HY-B0464

Miscellaneous

Safety:

22-40-63 Alfa Aesar B22995

36/37 Alfa Aesar B22995

6.1 Alfa Aesar B22995

Danger Alfa Aesar B22995

Danger Biosynth Q-201208

DANGER: POISON, irritates skin, eyes, lungs Alfa Aesar B22995

GHS06 Biosynth Q-201208

H301; H315; H319; H335 Biosynth Q-201208

H301-H351-H361 Alfa Aesar B22995

P261; P301+P310; P305+P351+P338 Biosynth Q-201208

P281-P301+P310-P308+P313-P321-P405-P501a Alfa Aesar B22995

Target Organs:

Others TargetMol T1613
Compound Source:

semisynthetic Microsource
[01500334]

Bio Activity:

AO;P4H TargetMol T1613

Hydralazine Hydrochloride is a direct-acting vasodilator that is used as an antihypertensive agent. MedChem Express

Hydralazine Hydrochloride is a direct-acting vasodilator that is used as an antihypertensive agent.; Target: Others; Hydralazine (apresoline) is a direct-acting smooth muscle relaxant used to treat hypertension by acting as a vasodilator primarily in arteries and arterioles. MedChem Express HY-B0464

Hydralazine Hydrochloride is a direct-acting vasodilator that is used as an antihypertensive agent.;Target: Hydralazine (apresoline) is a direct-acting smooth muscle relaxant used to treat hypertension by acting as a vasodilator primarily in arteries and arterioles. By relaxing vascular smooth muscle, vasodilators act to decrease peripheral resistance, thereby lowering blood pressure and decreasing afterload. However, this only has a short term effect on blood pressure, as the system will reset to the previous, high blood pressure necessary to maintain pressure in the kidney necessary for natriuresis. The long term effect of antihypertensive drugs comes from their effects on the pressure natriuresis curve. It belongs to the hydrazinophthalazine class of drugs [1]. Hydralazine may reduce blood pressure when compared to placebo in patients with primary hypertension, however this data is based on before and after studies, not RCTs. Furthermore, its effect on clinical outcomes re MedChem Express HY-B0464

Others MedChem Express HY-B0464

Others TargetMol T1613

Predicted data is generated using the ACD/Labs Percepta Platform – PhysChem Module

No predicted properties have been calculated for this compound.

Density:
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction:
Molar Refractivity:
#H bond acceptors:
#H bond donors:
#Freely Rotating Bonds:
#Rule of 5 Violations:

ACD/LogP:
ACD/LogD (pH 5.5):
ACD/BCF (pH 5.5):
ACD/KOC (pH 5.5):
ACD/LogD (pH 7.4):
ACD/BCF (pH 7.4):
ACD/KOC (pH 7.4):
Polar Surface Area:
Polarizability:
Surface Tension:
Molar Volume:

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HYDRALAZINE HYDROCHLORIDE C8H9ClN4 structure – Flashcards

Experimental Melting Point:

Experimental Flash Point:

Experimental Gravity:

Experimental Solubility:

Safety:

Target Organs:

Compound Source:

Bio Activity:

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