Exam I – Flashcard

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question
Which of the following is NOT LIKELY to characterize the approach of toxicology? A. Laboratory studies of the role of xenobiotics in carcinogens B. Studies of disease occurrence in populations according to person variables C. In vitro studies D. In vivo studies E. They all characterize the toxicologic approach
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B. Studies of disease occurrence in populations according to person variables
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What are the three "P's" that are the principal determinants of health worldwide? Choose all that apply. A. Pollution B. Population C. Property D. Poverty E. Parasites
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A. Pollution, B. Population, D. Poverty
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List three objectives relative to environmental health of the Healthy People 2020 program.
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toxic and hazardous substances, infrastructure and surveillance, air and water quality
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Why do children in comparison with adults represent a group that is especially vulnerable to environmental hazards? Choose the INCORRECT answer. A. Their immune systems are still developing B. They are developing more rapidly C. They may be exposed more often to toxicants in the soil D. They metabolize environmental chemicals more efficiently E. They may inadvertently ingest toxic substances
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D. They metabolize environmental chemicals more efficiently
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The epidemiologic risk transition is characterized by a: A. Population compromised of predominantly young individuals B. Growing burden of chronic, degenerative diseases C. Rapid increase in population D. High mortality rates E. None of the above
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B. Growing burden of chronic, degenerative diseases
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Stage 2 of the demographic transition demonstrates: A. Drop in mortality rates; high fertility rates B. Fertility and mortality rates are high C. Dropping fertility rates; more even age and sex distributions D. Increasing mortality rates; dropping mortality rates E. None of the above
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A. Drop in mortality rates; high fertility rates
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The effects of rapid growth of the world's populate include: A. Urbanization B. Overtaxing carrying capacity C. Food insecurity D. Loss of biodiversity E. All of the above
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E. All of the above
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Environmental health compromises those aspects of human health that are determined by: A. Physical factors B. Biological factors C. Social factors D. Psychosocial factors E. All of the above
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E. All of the above
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Which of the following statements is UNTRUE about ecosystems? A. Human beings are not considered to be a part of ecosystems B. An ecosystem is a dynamic complex of plant, animal and microorganism communities C. A temporary pond in a hollow tree can be an ecosystem D. Many ecosystems are being degraded E. All of these are untrue
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A. Human beings are not considered to be a part of ecosystems
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On Airs, Waters and Places was significant because: A. Identified an environmental cause of cancer B. Described safe and unsafe working environments C. Described the toxic properties of sulfur and zinc D. Emphasized the role of the environment in people's health E. None of the above
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D. Emphasized the role of the environment in people's health
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True/False: A contemporary environmental issue is the release of greenhouse gases and their possible contribution to climate change.
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True
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The contributions of epidemiology to environmental health include: A. Concern with populations B. Use of observational data C. Methodology for study designs D. Descriptive and analytic studies E. All of the above
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E. All of the above
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What are the two classes of epidemiologic studies?
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analytic, descriptive
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How to the two classes of epidemiologic studies differ?
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Analytic studies focus on hypotheses and the control groups while descriptive studies look for associations between variables and the outcome
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Environmental health science is concerned with agent, host and environmental factors in disease (epidemiologic triangle). What statement below is true about the triangle? A. Agent factors can include particles, toxic chemicals and pesticides B. The environment is the domain in which disease-causeing agents may exist C. The host is the person who affords the lodgment of an infectious agent D. Disease causality include three major factors: agent, host and environment E. All of the above are true
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E. All of the above are true
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Define prevalence in terms of disease frequency.
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the cases of a disease in a population
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Sir Percival Pott, who wrote Chirurgical Observations Relative to...: A. Was the father of modern biostatistics B. Established postulates for transmission of infectious disease C. Was an English anesthesiologist who used natural experiments D. Argued that the environment was associated with disease such as malaria E. Was a London surgeon who identified an environmental cause of cancer
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E. Was a London surgeon who identified an environmental cause of cancer
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Define incidence in terms of disease frequency.
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the new cases of a disease that happen in a population at risk within a specific time frame
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Identify the historical figure who was kong the first to expound on the role of environmental factors causing diseases: A. Sir Percival Pott B. John Snow C. Hippocrates D. Charles Miller III E. Socrates
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C. Hippocrates
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How do you calculate case fatality rate?
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(number of deaths from a disease/total number of cases of the same disease) x 100
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Which of the following statements is UNTRUE about case-control studies? A. Exposure to a factor is determined retrospectively B. They are a type of longitudinal design C. The measure of association is the odds ratio D. Exposure levels may be difficult to quantify precisely E. They can examine many potential exposures
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B. They are a type of longitudinal design
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Which of the following statements is TRUE about cohort studies? A. Subjects are classified to their exposure B. They are a type of longitudinal design C. They may be either prospective or retrospective D. The measure of association is most often the relative risk E. All of the above
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E. All of the above
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Hill's criteria of causality include: A. Strength B. Consistency C. Clarity D. A & B E. A, B, C
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D. A & B
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The limitations of environmental epidemiology include the fact that: A. Accurate assessment of exposure is difficult B. Environmentally associated diseases often have low incidence and prevalence C. Long latency periods often occur between initial exposures and disease outcomes D. The effects of exposures are often non-specific E. All of the above
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E. All of the above
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True/False: An ecologic epidemiological study is one that examines a group as the unit of analysis.
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True
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True/False: An odds ratio greater than 1 means that there is a positive association between the disease outcome and the exposure.
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True
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True/False: A relative risk less than 1 means that there is no association between exposure and outcome.
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False
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Define bias in environmental epidemiology.
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Systematic deviation of results or inferences from the truth
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Strength of environmental epidemiology.
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can address a large population
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Weakness of environmental epidemiology.
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lack of specificity of exposures
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The poisonous substance in the skin of frogs in the genus Dendrobates (poison dart frogs) is an example of: A. Toxicant B. Toxin C. Anthropogenic form of poison D. Synthetic xenobiotic E. None of the above
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B. Toxin
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The existence of dose-response relationships may be used to establish the following kinds of information: A. Causal association between a toxicant and biological effects B. Minimum dosage(s) needed to produce a biological effect C. Interactions between xenobiotics in producing biological effects D. All of the above E. A & B
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D. All of the above
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The concentration and toxicity of a chemical in the body are affected by: A. Route of entry into the body B. Received dose of the chemical C. Duration of exposure D. Individual sensitivity E. All of the above
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E. All of the above
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Of the following routes of exposure, which two are the most common? A. Intravenous B. Ingestion C. Intracranial D. Intramuscular E. Inhalation
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B. Ingestion, E. Inhalation
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Chronic exposures are those that last for: A. Less than 24 hours and occur once B. Less than 24 hours and occur more than once C. One month or less D. One to three months E. More than three months
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E. More than three months
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Exposure assessment refers to the question of: A. What are the health effects that this agent can cause? B. What is the relationship between dose and occurrence of health effects in humans? C. What exposures are currently experiences to anticipated under different conditions? D. What is the estimated occurrence of the adverse effect in a given population? E. None of the above
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C. What exposures are currently experiences to anticipated under different conditions?
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Risk characterization refers to the question of: A. What are the health effects that this agent can cause? B. What is the relationship between dose and occurrence of health effects in humans? C. What exposures are currently experiences to anticipated under different conditions? D. What is the estimated occurrence of the adverse effect in a given population? E. None of the above
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D. What is the estimated occurrence of the adverse effect in a given population?
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What type of interaction between two chemicals produces an effect that is EQUAL to their individual effects taken together? A. Additive B. Synergistic C. Potentiative D. Coalitive E. Antagonistic
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A. Additive
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What type of interaction between two chemicals produces an effect that is LESS than their individual effects taken together? A. Additive B. Synergistic C. Potentiative D. Coalitive E. Antagonistic
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E. Antagonistic
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An example of in vitro testing for toxicology is: A. Experiments with normal volunteers B. Experiments with volunteers who have had unintentional exposures C. Studies of animals exposed to toxins D. Dose-response assessments in human populations E. Experiments with cells derived from human source
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E. Experiments with cells derived from human source
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The concept of environmental justice specifies that: A. Immigrants can receive higher exposures to pesticides if their economic welfare is improved B. Industries can bypass environmental regulations in order to preserve their economic interests C. All people must receive fair treatment in the enforcement of environmental laws D. Decision-makers do not need to seek out the involvement of community members E. All of the above
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C. All people must receive fair treatment in the enforcement of environmental laws
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