Biology Chapter 12 Questions – Flashcards
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What clues did bacterial transformation yield about the gene?
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By observing bacterial transformation, Avery and other scientists discovered that the nucleic acid DNA stores and transmits genetic information from one generation of bacteria to the next.
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What role did bacterial viruses play in identifying genetic material?
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Hershey and Chase's experiment with bacteriophage confirmed Avery's results, convincing many scientists that DNA was the genetic material found in genes - not just in virus and bacteria, but in all living cells.
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What is the role of DNA heredity?
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The DNA that makes up genes must be capable of storing, copying, and transmitting the genetic information in a cell.
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What are the chemical components of DNA?
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DNA is a nucleic acid made up of nucleotides joined into long strands or chains by covalent bonds.
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What clues helped scientist solve the structure of DNA?
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The clues in Franklin's X-ray pattern enabled Watson and Crick to build a model that explained the specific structure and properties of DNA.
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What does the double-helix model tell us about DNA?
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The double-helix model explains Chargaff's rule of base pairing and how the two strands of DNA are held together.
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What role does DNA polymerase play in copying DNA?
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DNA polymerase is an enzyme that joins individual nucleotides to produce a new strand of DNA.
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How does DNA replication differ in prokaryotic cells and eukaryotic cells?
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Replication in most prokaryotic cells starts from a single point and proceeds in two directions until the entire chromosome is copied. In eukaryotic cells, replication may begin at dozens or even hundreds of places on the DNA molecule, proceeding in both directions until each chromosome is completely copied.
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List the conclusions that Griffith and Avery drew from their experiments.
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Griffith viewed from his experiments that through transformation, one type of bacteria because a harmful form, showing the transforming factor had to be a gene. Avery concluded from his work that specifically DNA, or nucleic acid transferred the bacterial genetic information.
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What was the experimental variable that Avery used when he repeated Griffith's work?
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Avery changed between types of molecules including protein, lipids, carbohydrates, and nucleic acid.
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What conclusion did Hershey and Chase draw from their experiment?
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Hershey and Chase concluded that DNA was the genetic material found in all living things.
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Why did Hershey and Chase grow viruses in cultures that contained both radioactive phosphorus and radioactive sulfur? What might have happened if they had used only one radioactive substance?
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The DNA contained sulfur, and by putting phosphorus on the DNA, the radioactive substance was easier to recognize because it stood out. It was the same with the protein coat which had lots of phosphorus but no sulfur.
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What are the three key roles of DNA?
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DNA must store, copy, and transmit information.
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Why would the storage of genetic information in genes help explain why chromosomes are separated so carefully during mitosis?
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Storing information is important because the loss of DNA will lead to a loss of genetic information.
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List the chemical components of DNA.
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DNA is a nucleic acid made up of nucleotides joined into long strands or chains by covalent bonds. The nitrogenous bases are made of four kinds: adenine, thymine, guanine, and cytosine.
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Why are hydrogen bonds so essential to the structure of DNA?
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Hydrogen bonds are weak chemical forces allowing DNA to easily split and create a template for new DNA to form from.
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Describe the discoveries that led to the modeling of DNA.
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Rosalind Franklin placed strands of DNA so they were parallel and took an X-Ray diffraction photograph showing the double helix. Watson and Crick then used this photograph to create an accurate model depicting the double helix twisting around.
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Why did scientists have to use tools other than microscopes to solve the structure of DNA?
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DNA is a very small substance and can't be seen with a simple microscope.
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Describe Watson and Crick's model of the DNA molecule.
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Watson and Crick's breakthrough model of DNA was a double helix, in which two strands of nucleotide sequences were wound around each other.
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How is DNA replicated?
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The DNA molecule separates into two strands and then produces two new complementary strands following the rule of base pairing. Each strand of the double helix of DNA serves as a template, or model, of the new strand.
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What is the role of DNA polymerase in DNA replication?
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DNA polymerase is an enzyme that joins individual nucleotides to produce a new strand of DNA. DNA also "proofreads" each new DNA strand, so that each molecule is a near-perfect copy of the original.
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Where and in what form is prokaryotic DNA found? Where is eukaryotic DNA found?
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In prokaryotes, DNA is a single, circular DNA molecule in the cytoplasm, containing nearly all the cell's genetic information. In eukaryotes, DNA is found in the nucleus, packaged into chromosomes. DNA packed together with proteins forms a substance known as chromatin.
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What could be the result of damaged DNA being replicated?
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Damaged DNA being replicated can alter genes and produce serious consequences.