Bio Midterm Cells and Cancer Multiple Choice – Flashcards

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Vinblastine, a drug that inhibits microtubule polymeration used to treat some forms of cancer. Cancer cells given vinblastine would be unable to
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separate chromosomes during cell division
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Cytochalasin D is a drug that prevents actin polymerization. A cell treated with cytochalasin D will still be able to
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E) move vesicles around the cell.
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Signals between the ECM and the cytoskeleton may be transmitted by
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integrins
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Liver cells manufacture glycoproteins, while adipose cells store fat. Which of the following subcellular structures is likely to be more prominent in liver cells than in adipose cells?
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Golgi Apparatus
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The formulation of a model for a structure such as the fluid mosaic model of the plasma membrane or for a process serves which of the following purposes
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It functions as a testable hypothesis
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Which of the following statements is true regarding the movement of substances across cell membranes
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Ions are unable to move through the phospholipid bilayer because the nonpolar tail regions of the phospholipids are hydrophobic
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the phosphate transport system in bacteria imports phosphate into a cell even when the concentration of phosphate outside the cell is much lower than the cytoplasmic phosphate concentration. Phosphate import depends on a pH gradient across the membrane-more H+ ions outside the cell than inside the cell. Phosphate transport is an example of
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cotransport
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Intravenous (IV) solutions administered to patients are normally isotonic. Which of the following is most likely if an IV of distilled water is administered to a patient
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The cells that are exposed to hypotonic solutions will expand as water moves osmotically into the cells from the blood
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Measurements of the amount of DNA per nucleus were taken on a large number of cells from a growing fungus. The measured DNA levels ranged from 3 to 6 picograms per nucleus. In which stage of the cell cycle did the nucleus contain 6 picograms of DNA?
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G2
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Proteins that are involved in the regulation of the cell cycle, and that show fluctuations in concentration during the cell cycle are called
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Cyclins
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Taxol is an anticancer drug extracted from the pacific yew tree. In animal cells, Taxol disrupts microtubule formation by binding to microtubules and accelerating their assembly from the protein precursor, tubulin. Surprisingly, this stops mitosis. Specifically, Taxol must affect
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the formation of the mitotic spindle
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The researcher in question measures the amount of new polypeptide (protein) production in embryos from 2-8 hours following fertilization and the results show a steady and significant rise in polypeptide concentration over that time. The researcher concludes that
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the resulting new polypeptides are due to translation of maternal mRNAs
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the researcher continues to study the reactions of the embryo to these new proteins and you hypothesize that he is most likely to see which of the following (while embryonic genes are still not being expressed)
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Spatial axes (anterior --> posterior etc) begin to be determined
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the researcher measures the concentration of the polypeptides from different regions in the early embryo and finds the following pattern (darker shading= greater concentration)
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the substance is produced in region 1 and diffuses toward region 5
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Density dependent inhibition is explain by which of the following?
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as cells become more numerous, the cell surface proteins of one cell contact the adjoining cells and they stop dividing
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Cancer can result from a variety of different mutational events. Which of the following is LEAST likely to result in the initiation of a cancerous tumor
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a defect in a cell cycle checkpoint prevents a cell from entering S phase.
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