ATI IMMUNE SYSTEM – Pharm – Flashcards

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question
When caring for a patient who is taking flutamide to treat prostate cancer, the health care professional should monitor the patient for which of the following adverse effects of the drug? Dehydration Gynecomastia Constipation Tachycardia
answer
Gynecomastia : Flutamide, an androgen receptor blocker, treats early and metastatic prostate cancer. It can cause gynecomastia, or growth of breast tissue, decreased libido, and
question
A health care professional is caring for a patient who is about to begin maraviroc (Selzentry) therapy. The health care professional should tell the patient to report which of the following adverse effects of the drug? (select all that apply). Paresthesias Cough Jaundice Fever
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Paresthesias: Maraviroc, a chemokine receptor 5 antagonist, can cause paresthesias, dizziness, and musculoskeletal pain. Cough: Maraviroc can cause a cough and upper respiratory infection Tinnitus Jaundice : Maraviroc can cause liver damage. The health care professional should tell the patient to report an allergic reaction, such as a rash, because it can precede liver damage, manifested as jaundice or abnormal pain. Fever: Maraviroc can cause a fever and sinus infection
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While assessing a patient who is receiving interferon alfa-2a (Roferon-A) to treat Kaposi's sarcoma, the health care professional should check for which of the following possible indication of an adverse reaction? Bradycardia Dilated pupils Fever Constipation
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Fever
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When talking to a patient who is about to begin vincristine therapy to treat lymphoma, the health care professional should include which of the following instructions? Increase fiber intake Report tinnitus or vertigo Take the drug with 8 oz of water Allow 4 hr before taking an antacid
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Increase fiber intake
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A health care professional should question the use of maraviroc (Selzentry) for a patient who has which of the following? Diabetes mellitus Meningeal infection Pancreatitis Non-chemokine receptor 5 (CCR5)-tropic HIV-1
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Non-chemokine receptor 5 (CCR5)-tropic HIV-1: Maraviroc, a CCR5 antagonist, acts by binding to CCR5 and preventing HIV-1 from entering the cell. It is only effective for patients who have CCR5-tropic HIV-1. It is contraindicated for those who do not have CCR5-tropic HIV-1.
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A health care professional should under that efuvirtide (Fuzeon) is an appropriate choice for patietns who have which of the following? Advanced prostate cancer Primary brain cancer Advanced HIV disease Metastatic ovarian cancer
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Advanced HIV disease: Enfuvirtide, a fusion inhibitor, treats HIV disease that is advanced or resistant to other types of treatment. Health care professionals should always give the drug along with other antiretroviral drugs.
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Unless there are any specific contraindications, which of the following immunizations should adults receive once each year? Varicella Tetanus Influenza Hepatitis B
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Influenza
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A health care professional is caring for a patient who is about to begin intrathecal cytarabine (DepoCyt) therapy to treat meningeal leukemia. The health care professional should explain that the patient should also receive which of the following drugs to reduce the risk of neurotoxicity? Diphenhydramine Leucovorin Folic acid Dexamethasone
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Dexamethasone
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A health care professional is caring for a patient who is about to begin delavirdine (Rescriptor) therapy to treat HIV-1. The health care professional should tell the patient to report which of the following adverse reactions to the drug? Rash Insomnia Rhinitis Alopecia
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Rash: Delavirdine, a non-nucleoside reverse transcriptase inhibitor, can cause a rash. The health care professional should tell the patient to report a rash, which can occur 1 to 3 weeks after therapy, because it can develop into Stevens-Johnson syndrome, a potentially life-threatening complication.
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A health care professional is caring for a patient who is about to start ritonavir (Norvir) and zidovudine (Retrovir) therapy to treat HIV-1. The health care professional should explain that the patient will receive ritonavir along with at least one reverse transcriptase inhibitor to: Prevent an infusion reaction Increase platelet production Protect healthy cells from the toxic effects of ritonavir Prevent drug resistence
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Prevent drug resistence: Give zidovudine, a nucleoside reverse transcriptase inhibitor, along with ritonavir, a protease inhibitor, to reduce the risk for drug resistance and to increase drug effectiveness. Monotherapy with zidovudine quickly results in drug resistance, as is also the case with monotherapy with ritonavir.
question
A health care professional is caring for a patient who is about to begin topotecan (Hycamtin) therapy to treat resistant, small-cell lung cancer. The health care professional should caution the patient about taking which of the following types of over-the-counter drugs while receiving the therapy? Folic acid St. John's wort Ibuprofen (Advil) Aluminum hydroxide (Amophojel)
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Ibuprofen (Advil): NSAIDs, anticoagulantas, and antiplatelet drugs increase the patient's risk for bleeding while receiving topotecan, a topoisomerase inhibitor. The health care professional should advise the patient against taking aspirin, ibuprofen (Advil), and other NSAIDs during the therapy.
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When caring for a patient who is receiving vincristine to treat lung cancer, the health care professional should monitor for which of the following findings that indicate an adverse effect? Weak hand grasps Constricted pupils Bradycardia Crackles
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Weak hand grasps: Vincristine ,a vinca alkaloid, can cause peripheral neuropathy. The health care professional should monitor deep-tendon reflexes and the strength and movement of the hands and feet. The health care professional should tell the patient to report paraesthesias or reduced sensation in the hands or feet.
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A health care professional is caring for a patient who is about to begin taking mercaptopurine (Purinethol) to treat leukemia. Which of the following instructions should the health care professional include when talking with the patient about the drug? (Select that all apply) Use contraception if pregnancy is a risk Perform oral hygiene frequently Avoid activities that require mental alertness Perform hand hygiene frequently Avoid activities that can cause serious injury
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Use contraception if pregnancy is a risk Perform oral hygiene frequently Perform hand hygiene frequently Avoid activities that can cause serious injury
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A health care professional is caring for a patient who is about to being taking tamoxifen (Soltamox) to treat breast cancer. The health care professional should recognize the need for cautious use of the drug if the patient also has which of the following? Cataracts COPD Diabetes mellitus Alcohols use disorder
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Cataracts
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When talking with a patient who is about to begin methotrexate (Trexall) therapy to treat non-Hodgkin lymophoma, the health care professional should include which of the following instructions? Take Echinacea supplements Use a soft-bristled toothbrush Take aspirin to reduce muscle pain Urinate every 4 hr
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Use a soft-bristled toothbrush
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A health care professional is assessing a patient following a trastuzumab (Herceptin) infusion to treat metastatic breast cancer. Which of the following findings indicates an adverse reaction to the drug? (select all that apply) Wheezing Dysrhythmias Hypotension Fever Ascites
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Wheezing Dysrhythmias Hypotension Fever
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A health care professional is caring for a patient who is about to begin receiving cisplatin to treat testicular cancer. The health care professional should tell the patient to report which of the following adverse effects? (select all that apply) Paresthesias Sore throat Flank pain Tinnitus Conjunctivitis
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Paresthesias Sore throat Flank pain Tinnitus
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A health care professional should question the use of anastrozole (Arimidex) for a patient who is Allergic to salicylates Premenopausal Hearing impaired Immunocompromised
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Premenopausal
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A health care professional is caring for a patient who is receiving IV carmustine (BiCNU) to treat multiple myeloma. The health care professional should recognize that the patient is at the greatest risk for infection for which of the following lengths of time after the infusion? 24 hr 1 week 2 weeks 4 to 6 weeks
answer
4 to 6 weeks
question
A health care professional should under that raltegarvir (Isenstress) treats patients who have which of the following? Hairy cell leukemia Thyroid cancer Kaposi's sarcoma Resistant HIV disease
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Resistant HIV disease
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A health care professional is about to administer enfuvirtide (Fuzeon) to a patient. The health care professional should perform which of the following actions? (select all that apply) Administer the drug subcutaneously Discard unused portion Roll the vial gently to reconstitute the solution Inject the solution at room temperature Expect a cloudy solution
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Administer the drug subcutaneously Inject the solution at room temperature Expect a cloudy solution
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When considering drug therapy options for a patient who has metastatic breast cancer that is positive for human epidermal growth factor receptor 2 (HER2), the health care professional should choose which of the following drugs? Tratuzumab (Herceptin) Imatinib (Gleevec) Leuprolide (Lupron) Flutamid
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Tratuzumab (Herceptin)
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A health care professional should question the use of cyclophosphamide for a patient who has which of the following? Raynaud's syndrome Dehydration Jaundice Charcot-Marie-Tooth syndrome
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Dehydration
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A health care professional is about to administer IV paclitaxel (Taxol) to a patient who has ovarian cancer. Which of the following actions should the health care professional take? (select all that apply) Give the patient an antihistamine Infuse the drug over 1 hr Administer the drug through non-PVC tubing Use an in-line filter Add heparin to the paclitaxel solution
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Give the patient an antihistamine Administer the drug through non-PVC tubing Use an in-line filter
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A health care professional is caring for a patient who is about to begin taking imatinib (Gleevec) to treat chronic myeloid leukemia. Which of the following instructions should the health care professional include when talking to the patient about taking the drug? (select all that apply) Clean fruits and vegetables thoroughly Increase calcium intake Weigh yourself daily Perform hand hygiene frequently Avoid herbal supplements
answer
Clean fruits and vegetables thoroughly Weigh yourself daily Perform hand hygiene frequently Avoid herbal supplements
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