Aminoglycosides/ gentamicin – Flashcards
Unlock all answers in this set
Unlock answersquestion
Therapeutic uses of gentamicin
answer
treats serious infections caused by G-, systemic UTI that started un urinary tract
question
Mode of Action for gentamicin
answer
bactericidal; inhibition of bacterial protein synthesis, destroy MO and may cause miscoding.
question
Contraindications of gentamicin
answer
pregos, lactation, severe renal disease, allergies to aminoglycosides, pre-existing hearing loss, myasthenia gravis/parkinsons
question
Precautions of gentamicin
answer
renal, hepatic disease, dehydration
question
Adverse Effects of gentamicin
answer
Serious:ototoxicity, nephrotoxicity, hepatic damage, thrombocytopenia, CNS numbness, photosensitivity, hypersensitivity, GI distress
question
Interactions of gentamicin
answer
it will inactivate aminoglycosides when mixed in the same IV solution; when administered with other ototoxic medications- the risk increases.
question
Gentamicin loves_____
answer
vancomycin
question
Pharmacokinetics of gentamicin
answer
IV: onset is immediate, peaks in 1-2 hours, IM onset is rapid, peaks in 1-2 hours
question
Nursing implications for gentamicin
answer
check hearing impairment, assess pt. nutritional status, store in frig until use
