AHIMA Pathophysiology and Pharmacology – Flashcards
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What characteristic do all individuals with cerebral palsy have?
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A form of motor disability
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Which term refers to excessive fluid collecting between the layers of the tunica vaginalis?
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Hydrocele
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Which of the following refers to fibrocystic breast disease?
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Fibrocystic breast disease is progressive development of fluid-filled cysts and fibrous tissue
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Which is/are sexually transmitted infection(s) usually considered asymptomatic in women?
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Chlamydia, gonorrhea, syphilis
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What is the probable source of an embolus causing a CVA?
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Common carotid artery
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Which of the following characteristics indicates the CSF is normal?
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Clear and colorless fluid
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Which of the following are common early significant signs of acute prostatitis?
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Soft, tender, enlarged gland and dysuria
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A hard nodule in the peripheral area of the prostate gland is typical of:
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A malignant tumor
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Which of the following STDs is considered to be a systemic infection?
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Syphilis
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What is characteristic of multiple sclerosis?
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Remissions and exacerbations
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Which of the following is the common first site for metastasis from prostatic cancer?
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Bone
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Which of the following applies to cerebral palsy?
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Cerebral palsy is nonprogressive brain damage to the fetus or neonate.
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What is a major predisposing factor to cervical cancer?
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Sexually transmitted diseases, particularly viral
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A brain tumor causes headache because the tumor:
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Stretches the meninges and blood vessel walls
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Which term refers to bleeding between menstrual periods?
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Metrorrhagia
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Which of the following applies to Parkinson's disease?
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Onset typically occurs in men and women over 60 years of age
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How do testicular tumors usually present?
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Hard, painless mass
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Which of the following statements applies to malignant brain tumors?
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Primary brain tumors rarely metastasize outside the CNS
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Which of the following is caused by an irregular curvature of the cornea or lens?
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Astigmatism
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What may result from cryptorchidism?
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Infertility and Testicular cancer
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What is the primary cause of type I diabetes?
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Destruction of pancreatic cells by an autoimmune reaction
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What is the cause of Tinea infections?
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Fungus
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How can pediculosis be diagnosed?
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The presence of nits at the base of hair shafts
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Which of the following does not usually develop as a complication of diabetes?
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Osteoporosis
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What disease does human papilloma virus cause?
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Human papillomavirus causes plantar warts
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Which of the following may cause insulin shock to develop in a diabetic person?
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Vomiting
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Which of the following would identify an open or compound fracture?
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The skin and soft tissue is exposed at the fracture site
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What is the prognosis for osteoarthritis?
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Damage is irreversible and usually progressive
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Which statement applies to menisci?
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They are fibrocartilage and they prevent excessive movement of joints.
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Which statement defines a sprain?
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Tear in a ligament
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Choose the statement that applies to type I diabetes mellitus.
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Onset often occurs during childhood
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All of the following predispose to osteoporosis except:
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Estrogen replacement therapy does not predispose a person to osteoporosis
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What is the cause of psoriasis?
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Increased mitosis and shedding of epithelium
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What is the most common cause of endocrine abnormalities?
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Benign tumor
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Which of the following is characteristic of osteoarthritis?
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Degeneration of articulating cartilage in the large joints
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What is a sign of a dislocation?
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Deformity at a joint.
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Where is a Colles' fracture located?
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Wrist (distal radius)
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What is the basic pathology of rheumatoid arthritis?
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A systemic inflammatory disorder due to an autoimmune reaction
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Which signs are typical of Graves' disease?
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Exophthalmos, heat intolerance, and restlessness are typical signs of Grave's disease.
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What is the definition of achalasia?
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Lack of a nerve plexus to relax the lower esophageal sphincter
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Where does urine flow?
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Urine flows from the collecting duct to the renal pelvis to the ureter to the bladder
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Which of the following describes the supply of bile following a cholecystectomy?
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Small amounts of bile are continuously secreted and flow into the duodenum
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Common causes of urolithiasis include all of the following except:
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Hyperlipidemia
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What is a cause of acute tubule necrosis and renal failure?
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Prolonged circulatory shock, sudden significant exposure to nephrotoxins, crush injuries or burns
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Which of the following is likely to lead to acute gastritis?
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Allergy to shellfish
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What is the primary action of the diuretic furosemide?
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Used to eliminate water and salt from the body
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Which of the following is true of the visceral peritoneum?
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It forms the outer covering of the stomach and intestines The visceral peritoneum is the outer covering of the stomach and intestines.
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Oral candidiasis is considered to:
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Be an opportunistic fungal infection of the mouth
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Which disease is manifested by dysuria and pyuria?
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Cystitis
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An agent used to promote weight loss is:
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Orlistat
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What is a common cause of gastroenteritis due to Salmonella?
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Raw or undercooked poultry or eggs
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A digestant is intended to:
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Replace deficient enzymes of the gastrointestinal tract
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What is a predisposing factor to bladder cancer?
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Exposure to chemicals and cigarette smoke
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What is thie primary cause of esophageal varices?
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Portal hypertension
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Which of the following congenital defects is a common cause of cystitis in young children?
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Vesicoureteral reflux
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Which of the following apply to cleft palate?
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The hard and soft palates do not fuse during the first trimester
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Which of the following is the primary site for absorption of nutrients?
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Ileum
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What is/are common locations for oral cancer?
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Floor of the mouth or tongue borders
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uretics are generally administered in the:
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Morning
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Which of the following activities does not require muscle contractions and energy?
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Quiet expiration
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What does orthopnea mean?
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Difficulty breathing in a recumbent position
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What describes the basic pathophysiology of myocardial infarction?
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Total obstruction of a coronary artery causes myocardial necrosis
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Which of the following is a major factor contributing to the current increase in cases of tuburculosis?
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The increase in immunodeficient individuals
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When does flail chest occur?
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Several ribs are fractured at two sites
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What does the term arteriosclerosis specifically refer to?
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Degeneration with loss of elasticity and obstruction in small arteries
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Which of the following would be significant signs of bronchiectasis?
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Chronic cough producing large quantities of purulent sputum
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Which of the following drugs decreases sodium and fluid retention in the body?
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Hydrochlorothiazide (drug prescribed to decrease Na and fluid retention in the body)
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Why does ventricular fibrillation result in cardiac arrest?
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Insufficient blood is supplied to the myocardium
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Which are predisposing factors to thrombus formation in the circulation?
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Damaged blood vessel walls, immobility, and prosthetic valves are all predisposing factors to thrombus formation in the circulation.
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What are typical signs and symptoms of epiglottitis?
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Sudden fever, sore throat, and drooling saliva
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What is the cause of chronic bronchitis?
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Chronic irritation, inflammation, and infection of the larger airways
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Loss of blood supply in a limb may lead to:
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Necrosis, ulcers, gangrene
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How is acute sinusitis usually manifested?
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Severe localized pain and tenderness in the face
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What is the most common cause of viral pneumonia?
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Influenza virus
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An atheroma develops from:
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Accumulated lipids, cells, and fibrin where endothelial injury has occurred
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Factors that may precipitate an angina attack include all of the following except:
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Walking down stairs
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What drug is taken in small doses on a continuing basis to reduce platelet adhesion?
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Acetylsalicylic acid (ASA or Aspirin)
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Cigarette smoking is a risk factor in coronary artery disease because it:
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Promotes thrombus formation
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Which are the first arteries to branch off the aorta?
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Coronary arteries
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Which of the following is an enzyme that is used in cancer chemotherapy?
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Pegaspargase
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What are typical early general signs/symptoms of anemia?
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Pallor, dyspnea, and fatigue
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Non-Hodgkin's lymphoma differs from Hodgkin's lymphoma in that non-Hodgkin's lymphoma usually presents as:
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Multiple, scattered, enlarged and painless lymph nodes
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Radiation therapy destroys:
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Primarily rapidly dividing cells
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One reason for staging a malignant tumor at the time of diagnosis is to:
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Determine the best treatment and the prognosis
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Individuals with type O blood are considered to be universal donors because their blood:
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Type O blood lacks A and B antigens.
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With the acute leukemias, the increased number of malignant leukocytes leads to:
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Decreased hemoglobin, thrombocytopenia, constant bone pain, and splenomegaly
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What would be the result of a reduced number of erythrocytes in the blood?
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A decreased hematocrit
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Glucocorticoids are often prescribed during a course of chemotherapy and radiation because:
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Inflammation around the tumor may be reduced
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Which of the following is typical of Hodgkin's disease?
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Initial tumor is single, painless, enlarged lymph node, often cervical
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Petechiae and purpura are common signs of:
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Increased bleeding tendencies
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What is the grading of newly diagnosed malignant tumors based on?
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Degree of differentiation of the cells
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What is a common predisposing factors to leukemia?
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Exposure to radiation
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Which of the following is an example of an antiandrogen?
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Nilutamide, bicalutamide, flutamide, megestrol
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Hydroxyurea is believed to function in cancer therapy by:
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Interfering with the formation of DNA
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Which anemia is considered to result from a malabsorption problem?
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Pernicious anemia
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The common local effects of an expanding tumor mass include:
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The common local effects of an expanding tumor mass include obstruction of a tube or duct and cell necrosis and ulceration.
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Which of the following is a characteristic of a benign tumor?
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Cells appear relatively normal
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What is the cause of sickle-cell anemia?
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A defective gene inherited from both parents
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Iron-deficiency anemia frequently results from any of the following except:
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Iron-deficiency anemia does not result from diabetes mellitus.
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The role of memory cells is to:
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Memory cells support the immune response by recognizing certain antigens
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What method do viruses use to replicate?
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Using a host cell to produce and assemble components
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Prolonged administration of glucocorticoids such as prednisone, may cause:
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Prolonged administration of glucocorticoids may cause atrophy of lymphoid tissue and decreased protein synthesis.
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Varicella is another word for
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Chickenpox
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The warmth and redness related to the inflammatory response results from:
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Increased blood flow into the area
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Glucocorticoids are used to treat inflammation because they directly:
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Decrease capillary permeability
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Which area of the body is sterile?
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Stomach
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1 kg equals _____ pounds.
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2.2 pounds.
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HIV is transmitted by:
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Blood, semen, and vaginal secretions from an infected person
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Which of the following is not classified as protozoa?
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Mycoplasma pneumonia
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Humoral immunity is mediated by:
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Humoral immunity is mediated by B lymphocytes.
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A serious side effect of the immunosuppressives is:
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An increased susceptibility to infections
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Routine application of sun block to skin would be an example of:
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Preventative measure
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Which of the following is a factor that may affect drug dosage?
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Weight
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Most likely cause of an iatrogenic disease?
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An unwanted effect of a prescribed drug
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Which of the following is an agent used to treat the anemia that often occurs after chemotherapy?
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Epoetin alfa
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Which of the following is an example of an antitumor antibiotic?
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Dactinomycin
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Neoplasms are caused by?
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Uncontrolled cell division
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The most critical adverse effects of chemotherapy and radiation therapy include:
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Thrombocytopenia and Leukopenia
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What is the spread of malignant cells through blood and lymph to distant sites called
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Metastasis
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ABCESS
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A localized pocket of infection or purulent exudate surrounded by inflammation.
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ACETAMINOPHENEN
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An analgesic for mild pain and antipyretic. Does not lessen inflammatory response.
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ACETYLSALICYLIC ACID
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Drug taken in small doses on a continuing basis to reduce platelet adhesion. Treats pain, fever, arthritis, and inflammation. It may also be used to reduce the risk of heart attack.
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ACUTE RENAL FAILURE
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Prolonged severe vasoconstriction and reduced blood supply to the kidney. Reduced blood supply causes tubular necrosis, obstruction of filtrate flow and cessation of glomerular filtration or shutdown. In some cases permanent kidney damage may result.
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ALZHEIMER'S DISEASE
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Progressive loss of intellectual function that eventually interferes with life. Progressive cortical atrophy (leads to dilated ventricles, widening of sulci). Deficit of Acetylcholine (ACh). Cause is unknown. Form of dementia. Typical early signs are behavioral changes and inability to reason.
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AMYOTROPHIC LATERAL SCLEROSIS
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Degeneration of upper and lower motor neurons. Progressive wasting of skeletal muscle. Intellect persists. Leads to paralysis. Typical early signs are weakness and muscle atrophy in upper limbs.
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ANAPHYLAXIS
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Life-threatening, systemic hypersensitivity reaction causing circulatory shock and airway obstruction. It typically causes a number of symptoms including an itchy rash, throat swelling, and low blood pressure. Primary treatment is injection of epinephrine.
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ANGINA PECTORIS
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Transient chest pain resulting from myocardial hypoxia when demands on the heart increase or oxygen supply to the heart is impaired.
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ANKYLOSING SPONDYLITIS
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Long term type of arthritis. Affects bones/joints at the base of the spine where it connects with the pelvis. Joints become swollen/inflamed. Overtime, the affected spinal bones join together.
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ANTICHOLINESTERASE AGENTS
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May be prescribed as a temporary relief of Myasthenia Gravis.
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ANTICOAGULANTS
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Class of drugs that work to prevent the coagulation of blood. Such substances occur naturally in leeches and blood-sucking insects.
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ANTIHYPERTENSIVE DRUGS
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Classes of drugs used only in the treatment of hypertension: a common adverse effect is orthostatic hypertension.
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ANTIVIRAL DRUGS
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Class of medication used specifically for treating viral infections. Like antibiotics for bacteria, specific antivirals are used for specific viruses. Unlike most antibiotics, antiviral drugs do not destroy their target pathogen; instead they inhibit their development.
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AORTIC STENOSIS
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The aortic valve doesn't fully open. Decrease in blood flow from the heart. Aorta is the main artery carrying blood out of the heart. When blood leaves the heart it flows through they aortic valve, into the aorta.
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ATHERSCLOROSIS
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Hardening of the arteries. It occurs when fat, cholesterol, and other substances build up in the walls of arteries and form hard structures called plaques. Over time, these plaques can block the arteries and cause problems throughout the body. Elevated blood lipid levels. Common cause of angina, myocaridial infarction and/or stroke.
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ATRIOVENTRICULAR VALVES
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A valve in the heart through which blood flows from the atria to the ventricles.Between left atrium and left ventricle is the mitral (bicuspid) valve. Between right atrium and right ventricle is the tricuspid valve.
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ATROPHY
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Degeneration and wasting of tissue, organs, or muscle due to decrease in cell size resulting in a reduced tissue mass. Partial or complete wasting away of a part of the body.
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AUTOIMMUNE DISEASE
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Condition that occurs when the immune system mistakenly attacks and destroys healthy body tissue.
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BACTERIAL ENDOSPORE
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Dormant, non-reproductive and enzymatically inert forms of bacterial vegetative cells. Hardy, defensive structures. Sporulation is the ability to form endospores (rare talent). Can survive high temperatures and dry environment.
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BASILAR FRACTURE
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Occurs at the base of the skull and are often accompanied by leaking of CSF through the ears or nose. May occur when forehead hits a car windshield.
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B-CELL LYMPHOMA
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Non-Hodgkin's lymphoma. Multiple node involvement scattered throughout the body and a non-organized pattern of widespread metastases, often present at diagnosis.
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BIOSYNTHETIC SKIN SUBSTITUTE
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Acts as a temporary wound covering. The body's own cells migrate in, heal the wound and replace the skin substitute. An "artificial skin" graft material when skin is damaged.
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BLOOD TYPES
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Blood type is ABO and Rh Group. Determined by the presence of specific antigens on the cell membranes of that persons erythrocytes. Error in typing when transfusing leads to erythrocyte hemolysis.
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BRONCHOGENIC CARCINOMA
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Arising from the bronchial epithelium. Most common type of malignant lung cancer.
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CANCER
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Malignant Neoplasia. Uncontrolled growth of abnormal cells in the body. Cancerous cells are also called malignant cells.
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CARDIAC ARREST
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Cessation of all activity in the heart. No conduction of impulses, and the ECG shows a flat line.
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CARDIAC ARRHYTHMIAS
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Irregular heart rhythms. Disturbances in the normal rhythm of the heartbeat. Tachycardia = Rapid HR Bradycardia = Slow HR A-Fib/Flutter = Irregular or Rapid HR
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CARRIER
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a person hosting an infectious pathogen, who shows no signs of the disease, but could transit the infection to others (Also may pass on genetic abnormalities while being asymptomatic - i.e. Sickle Cell Trait)
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CAUSES
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the known cause of and factors predisposing to specific diseases
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CELL
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The base unit that is the functional and structural unit in the human body. Smallest unit of life that can replicate independently. Eukaryotes = Contain a nucleus Prokaryotes = Don't contain a nucleus
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CEREBROVASCULAR ACCIDENT (STROKE)
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A CVA or a stroke is an infarction of brain tissue resulting from a thrombus, embolus or hemorrhage and causing permanent loss of brain tissue.
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CHLAMYDIA
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A common STD that may cause PID in women. Pathogen = Chlamydia Trachomatis (gram negative obligate intracellular parasite, which requires a host cell to reproduce). Mild dysuria & discharge or asymptomatic.
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CHOLELITHIASIS
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Refers to formation of gallstones, which are masses of solid material or calculi that form in the bile.
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CHOLOEDOLITHIASIS
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Reduced to minute particles or fragments. (of a fracture) producing multiple bone splinters.
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COMMINUTED
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Fracture in which there are multiple fracture lines and bone fragments.
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COMPRESSION FRACTURE
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Common in the vertebrae. Occurring when a bone is crushed or collapses into small pieces.
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COUMADIN
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Helps to prevent new blood clots from forming, and helps to keep existing blood clots from getting worse. This medicine is a blood thinner (anticoagulant).
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CULTURE & SENSITIVITY TESTS
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Evaluation of fluid, tissue or other products of the body to look for the presence of abnormal cells indicating presence of viruses, bacteria or fungi. Tests performed to identify the type of bacteria and to determine which antibiotics can successfully fight an infection.
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CYSTIC FIBROSIS
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Genetic disorder affecting the exocrine glands causing thick mucus to obstruct the bronchioles in the lungs, pancreatic and biliary ducts. Children born with cystic fibrosis will have delayed growth and development due to mucus plugs obstructing the flow of pancreatic enzymes. Respiratory infections are common. Inherited disorder (recessive gene).
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DETACHED RETINA
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A tear in the retina deprives the retinal cells of nutrients which, if prolonged, may cause permanent loss of vision. Retina tears away from the underlying choroid. No pain, but increasing dark area in the visual field.
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DIABETES MELLITUS
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Caused by a relative deficit of insulin secretion from the beta cells in the islets of Langerhans or by the lack of response by cells to insulin. High levels of sugar in the blood. Leads to hyperglycemia and multiple metabolic abnormalities - can occur when pancrease does not secrete sufficient insulin or body cells are resistant to insulin's effects - the glucose level in the blood becomes quite high after the ingestion of carbohydrates
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DIGOXIN
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Treats certain heart rhythm problems (atrial fibrillation). Also used to treat heart failure, usually in combination with a diuretic (water pill) and an angiotensin-converting enzyme (ACE) inhibitor. Drug that improves cardiac efficiency by slowing the heart rate and increasing the force of cardiac contractions.
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DYSPLASIA
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Tissue in which the cells vary in size and shape, large nuclei are frequently present, and the rate of mitosis is increased. Atypical cells, malignant changes. Chronic irritation infection.
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EDEMA
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The accumulation of excess fluid in cells, tissue, or a cavity, resulting in swelling.
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ELECTROENCEPHALOGRAM
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Recording of electrical activity along the scalp. EEG measures voltage fluctuations resulting from ionic current flows within the neurons of the brain. Diagnostic tool used to both confirm a diagnosis of seizures and classify the type of seizure.
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EMBOLUS/THROMBUS
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Detached, traveling intravascular mass carried by circulation, which is capable of clogging arterial capillary beds at a site distant from its point of origin. A mass (e.g., blood clot, air, fat, tumor cells) that breaks away into the circulation and obstructs a blood vessel.
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ENCEPHALITIS
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Irritation and swelling (inflammation) of the brain, most often due to infections. Often transmitted by mosquitoes.
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ENDOMETRIAL CARCINOMA
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Cancer that starts in the endometrium, the lining of the uterus (womb). Early sign are minor vaginal bleeding or spotting.
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ENDOMETRIOSIS
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Defined as the presence of endometrial tissue outside the uterus, on structures such as the ovaries, ligaments, or colon. Female health disorder that occurs when cells from the lining of the womb (uterus) grow in other areas of the body. This can lead to pain, irregular bleeding, and problems getting pregnant (infertility).
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ENTAMOEBA HISTOLYTICA
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Anaerobic parasitic protozoan, part of the genus Entamoeba. Predominantly infecting humans and other primates, E. histolytica is estimated to infect about 50 million people worldwide. Transmitted by cysts in feces, contaminating food and water.
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EPIDURAL HEMATOMA
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Type of traumatic brain injury (TBI) in which a buildup of blood occurs between the dura mater (the tough outer membrane of the central nervous system) and the skull. Contusion, bruise, or clot of blood located between dura and skull.
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EPINEPHRINE
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Treats severe allergic reactions (including anaphylaxis) in an emergency situation. Bronchodilator with rapid action, and short duration.
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EPITHELIAL CELLS
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First cells to be most affected by chemo and radiation treatments.
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ETIOLOGY
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The study of the causes of a disease.
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FAT EMBOLI
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Type of pulmonary emboli from the bone marrow resulting from fracture of a large bone like the femur causing pulmonary inflammation and obstruction.
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FULL-THICKNESS BURN
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Destroys all skin layers - dry, firm, charred or white surface after burn.
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HYDROCHLOROTHIAZIDE (HCTZ)
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Used alone or together with other medicines to treat high blood pressure and fluid retention (edema). This medicine is a diuretic (water pill).
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GENERAL CUTANEOUS VASODILATION
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What increases peripheral blood flow during periods of the inflammatory process?
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GLOMERULONEPHRITIS
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Type of kidney disease in which the part of your kidneys that helps filter waste and fluids from the blood is damaged. Acute bilateral glomerulonephritis may cause acute renal failure.
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GLUCOCORTICOIDS
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Class of steroid hormones that bind to the glucocorticoid receptor, which is present in almost every vertebrate animal cell. Long-term drug use does not give relief of fever, but may result in decreased secretion from the adrenal cortex gland leading to Cushing's disease.
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GREENSTICK FRACTURE
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A fracture in a young, soft bone in which the bone bends and breaks.
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GUILLAIN-BARRE SYNDROME
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A serious disorder that occurs when the body's defense (immune) system mistakenly attacks part of the nervous system. This leads to nerve inflammation that causes muscle weakness and other symptoms. Autoimmune disorder with inflammation and demyelination of peripheral nerves leading to ascending paralysis.
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HEMORRHAGIC CVA
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A hemorrhagic stroke occurs when a blood vessel in part of the brain becomes weak and bursts open, causing blood to leak into the brain. Type of CVA with poorest prognosis for survival.
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HEPARIN
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Prevents clots in the blood vessels before or after surgery or during certain medical procedures. Also treats certain blood, heart, and lung disorders and helps diagnose and treat certain bleeding disorders. This medicine is a blood thinner.
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HISTAMINE
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Organic nitrogenous compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter. Histamine is involved in the inflammatory response.
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HIV POSITIVE
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Status = Presence of human immunodeficiency virus (HIV) and antibodies in the blood, without signs of active infection . HIV infection impairs both humeral and cell-mediated immunity.
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HODGKIN'S LYMPHOMA
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A malignancy involving the T-lymphocytes. Cancer of lymph tissue. Lymph tissue is found in the lymph nodes, spleen, liver, bone marrow, and other sites.
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HOST-VERSUS-GRAFT
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Transplant rejection that occurs when the host, or recipient's immune system rejects the graft or transplanted organ.
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HUNTINGTON'S DISEASE OR CHOREA
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An inherited disorder with onset in adulthood where progressive atrophy of the brain affects motor and cognitive functions one of three genetic diseases with disorders of biochemical abnormalities involving the neurotransmitters of the brain - other two are Bipolar disorders and schizophrenia.
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HYPERTENSION
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This disease process is most likely to cause ischemia and loss of function to the brain, kidneys, and retinas when uncontrolled.
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HYPERTROPHY OF THE HEART
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Increased size of the cardiac muscle due to increased size of individual cells causes.
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INCUBATION PERIOD
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The time between exposure to the microorganism and the onset of signs or symtoms.
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INTERMITTENT CLAUDICATION
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Leg pain associated with exercise due to muscle ischemia is called.
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KAPOSI'S SARCOMA
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A skin cancer now frequently associated with AIDS.
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LEFT VENTRICULAR OUTPUT
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Equal to right ventricular output in a normal, healthy heart.
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LESION
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Term used to describe a specific local change in the tissue.
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LEUKEMIAS
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A form of cancer primarily treated by chemotherapy
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LOCAL VASOCONSTRICTION
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May be achieved by the application of ice to a localized injury to reduce edema.
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LOW DENSITY LIPOPROTEINS
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Promotes the formation of atheromas
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MALIGNANT NEOPLASM
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Often referred to as cancer.
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MELENA
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Black, tarry stool caused by bleeding in the digestive tract (not occult blood).
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MENINGITIS
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An infection of the meninges covering the brain and spinal cord causing increased intracranial pressure and Infection.
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MICROBIAL MUTATION
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Viral changes slightly during replication.
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MULTIPLE MYELOMA
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A form of cancer involving the plasma cells, which invade the bone marrow, destroying bones in the vertebrae, ribs, pelvis, and skull.
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MULTIPLE SCLEROSIS
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A group of chronic progressive disorders, resulting from demyelination in the brain, spinal cord, and cranial nerves.
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MYASTHENIA GRAVIS
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A chronic autoimmune neuromuscular disorder that may be temporarily relieved by anticholinesterase agents.
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MYOCARDIAL INFARCTION
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Obstruction of a coronary artery causes necrosis of heart tissue, impairing pumping ability and/or conduction (heart attack).
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NECROSIS
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Death or destruction of tissue.
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NEUTROPENIA
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A deficit of neutrophils in the blood caused by chemo and radiation leading to high risk for infections.
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ORGAN SYSTEM
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A group of organs performing similar or complimentary functions within the body.
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OSTEODYSTOPHY
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Associated with chronic renal failure due to the failure of the kidney to activate Vitamin D.
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OSTEOPOROSIS
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Loss of bone density and mass leading to fragile bones and spontaneous fractures.
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ORTHOSTATIC HYPOTENSION
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A common adverse effect of anti-hypertensive medications.
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OTORRHEA
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A seepage of CSF from the ear, especially a purulent one.
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PARANEOPLASTIC SYNDROME
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The effects of substances such as hormones secreted by the tumor cells.
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PARKINSON'S DISEASE
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Early manifestations - tremors while at rest of the hands and difficulty in initiating voluntary movements.
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PATHOLOGIC FRACTURE
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Stress or pressure fractures due to disease , chemo, or radiation.
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PERICARDIAL CAVITY
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A potential space containing a very small amount of serous fluid.
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PERICARDITIS
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Inflammation or infection of the pericardium (a fibrous sac surrounding the heart). Causes may be infection, abnormal immune responses, injury, malignant neoplasms.
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PLEURAL EFFUSION
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Excessive fluid in the pleural cavity.
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POST-POLIO SYNDROME
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Late signs may be progressive fatigue and weakness.
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PRIMARY IMMUNE RESPONSE VS SECONDARY IMMUNE RESPONSE
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Primary Immune response is responding to precise microorganism that immune system has not yet encountered. Secondary Immune response is responding to an exact repeat of microorganism or virus (not a mutated form).
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PROGNOSIS
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The probable outcome of a disease.
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PROSTAGLANDINS
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Chemical mediator along with histamine.
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PULMONARY EDEMA
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Causes severe hypoxia because of increasing difficulty in expanding the lungs.
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PULMONARY EMBOLUS
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An obstruction of a blood vessel in the lungs.
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RAPID HEALING
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What is promoted by closely approximated edges of a wound?
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REGENERATION
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Tissue repair through replacement by identical functioning cells.
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REGIONAL ILEITIS
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Chronic inflammatory disorder affecting the ileum interfering with absorption of proteins and nutrients causing protein and vitamin deficiency.
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RHEUMATIC HEART DISEASE
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Most common acquired heart disease in children in many countries of the world, especially in developing countries. The global burden of disease caused by rheumatic fever currently falls disproportionately on children living in the developing world, especially where poverty is widespread. RHD is a chronic heart condition caused by rheumatic fever that can be prevented and controlled. Rheumatic fever is caused by a preceding group A streptococcal (strep) infection. Treating strep throat with antibiotics can prevent rheumatic fever.
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SCAR TISSUE
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Consists primarily of collagen fibers.
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SECONDARY POLYCTHEMIA
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Associated with severe chronic bronchitis.
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SECRETIN
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One of the hormones that is secreted by the duodenum when acidic chyme reaches it and stimulates the pancreas during the digestive process.
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SEROUS EXUDATE
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Serous - watery secretion.
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SEVERE ADULT RESPIRATORY SYNDROME - (SARS)
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An emerging viral infection (coronavirus) that causes severe congestion in the lungs and hypoxia.
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SHOCK
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Decreased circulating blood and tissue perfusion is caused by ______.
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SICKLE CELL TRAIT
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Not a disease, but having it means that a person has inherited the sickle cell gene from one of his or her parents. People with SCT usually do not have any of the symptoms of sickle cell disease (SCD) and live a normal life.
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SPINA BIFIDA
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A developmental congenital disorder caused by the incomplete closing of the embryonic neural tube. Some vertebrae overlying the spinal cord are not fully formed and remain unfused and open. If the opening is large enough, this allows a portion of the spinal cord to protrude through the opening in the bones.
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SQUAMOUS CELL CARCINOMA
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A type of skin cancer. Skin cancer falls into two groups: nonmelanoma and melanoma. Squamous cell is a type of nonmelanoma skin cancer. Painless, malignant tumor of the epidermis.
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STREPTOKINAS
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An enzyme secreted by several species of streptococci that can bind and activate human plasminogen. SK is used as an effective and inexpensive thrombolysis medication in some cases of myocardial infarction and pulmonary embolism.
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STROKE VOLUME
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Volume of blood pumped from one ventricle in one contraction.
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The outer STRUCTURE OF A VIRUS
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A protein coat which encases either RNA or DNA.
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SYMPATHETIC NERVOUS SYSTEM STIMULATION
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Causes the heart rate to increase.
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PARASYMPATHETIC NERVOUS SYSTEM STIMULATION
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Slows down heart rate.
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SYPHILIS
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Bacterial Infection STD.
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SYSTEMIC LUPUS ERYTHEMATOSUS
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An autoimmune disease caused by immune complex deposits of antinuclear antibodies and is distinguished clinically by inflammation in multiple organs. (Not by a rash on any part of the body for this exam).
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T-CELL LYMPHOMA
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A malignancy involving the T-lymphocytes that first develops in a single lymph node then spreads in an orderly fashion.
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TETRALOGY OF FALLOT
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A congenital heart defect that includes pulmonary stenosis, ventricular septal defect, dextroposition of the aorta, and right ventricular hypertrophy.
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THALASEMIA
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A genetic defect in hemoglobin causes premature hemolysis of RBCs and severe anemia.
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TRANSIENT ISCHEMIC ATTACKS
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Vascular disorder caused by temporary reductions in blood supply in an area of the brain causing brief impairment of speech or motor function.
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TRANSMISSION OF MICROBES
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Disease is spread through: Direct contact: touching an infectious lesion or sexual intercourse Indirect contact: involves intermediary such as a contaminated hand or food, objects Vector borne: when an insect or animal serves as an intermediary host in a disease such as malaria Droplets and airborne: involves inhaling respiratory and salivary excretion of an infected person directly or indirectly
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TRICHOMONIASIS
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Causes inflammation of the vagina with a copious yellow discharge and foul odor.
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UNCONTROLLED HYPERTENSION
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This disease process affects these body organs - Primarily: kidney, heart, and retinas.
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VARICOSE VEINS
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Dilated and tortuous areas of superficial or deep veins in the legs.
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VENTRICULAR OUTPUT
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The volume of blood ejected by a ventricle in one minute and depends on heart rate and stroke volume - will be equal for right and left ventricle in a normal healthy heart.
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VITAMIN K
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Required by the liver to synthesize prothrombin - NOT required by bone marrow to synthesize hemoglobin.
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YEASTS
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Cause opportunistic infections.
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BETA-ADRENERGIC BLOCKING DRUGS
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Prescribed to decrease the sympathetic stimulation of the heart and reduce the force of contractions.
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FIBRINOGEN
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Protein that is formed into solid fibrin strands during the clotting process and forms a fibrin mesh around the area in an attempt to localize the injurious agent.
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HEART MURMUR
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Defective valves that leak or do not open completely cause a
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FEVER
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Caused by the release of pyrogens during an inflammatory process.
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CONTACT DERMATITIS
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Skin rash resulting from hypersensitivity reaction or direct irritation following direct exposure to a substance.
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STAPHYLOCOCCI
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Bacteria that form a cluster of spheres are called.
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ZIDOVUDINE
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Treats HIV and AIDS infection. Zidovudine does not cure HIV or AIDS, but combinations of drugs that treat HIV infection may slow progress of the disease.
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GLUCOCORTICOIDS
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Medications that cause atrophy of lymphoid tissue and decreased protein synthesis.
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IATROGENIC DISEASE
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A treatment, a procedure or an error may cause a disease, which is then described as iatrogenic. Examples of iatrogenic disease are a bladder infection following catheterization, or bone marrow damage caused by a prescribed drug.
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CUSHING'S SYNDROME
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Disorder that occurs when your body is exposed to high levels of the hormone cortisol. It may also occur if you take too much cortisol or other steroid hormones. This can be caused by taking glucocorticoid drugs, or diseases that result in excess cortisol, adrenocorticotropic hormone (ACTH), or CRH levels.
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ADDISON'S DISEASE
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Adrenal glands don't produce enough of their hormones. Deficiency of adrenocortical secretions, the gluticocorticoids, mineralcorticoids, and androgens. Cause is usually an autoimmune reaction.
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MICROFLORA - RESIDENT/NORMAL FLORA
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Different species inhabit various areas of the body.
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LOCAL SIGNS OF INFECTION
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Pain, erythema and swelling.
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CHEMICAL MEDIATORS - INFLAMMATION
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Histamine, serotonin, prostaglandins and leukotrienes.
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TID
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3 times per day.
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BENADRYL - PRIMARY SIDE EFFECT
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Drowsiness.
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MANIFESTATIONS OF A DISEASE
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Signs and Symptoms.
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NEUTROPHILS
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Phagocytic cells.
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BODY TEMPERATURE - CELSIUS
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37 Degrees Celsius (98.6 Degrees Fahrenheit)
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NOSOCOMIAL INFECTION
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Infection acquired in a hospital or medical facility
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MACROPHAGES
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Which cells are required to process and present antigens from foreign material as the initial step in the immune response?
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Which of the following causes bronchodilation?
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Epinephrine
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What happens in the lungs after the diaphragm relaxes?
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Air is forced out of the lungs
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Which statement describes a coronary artery bypass procedure?
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Attaching a section of vein to the coronary artery proximal and distal to the obstruction
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Obstruction in the upper airway would be indicated by:
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Stridor
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What will a partial obstruction in a coronary artery likely cause?
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Angina attack
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What are early signs and symptoms of infectious rhinitis?
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Serous nasal discharge, congestion, and sneezing
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What is the most common cause of death immediately following a myocardial infarction?
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Cardiac arrhythmias
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What are the early signs or symptoms of myocardial infarction?
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Persistent chest pain radiating to the left arm, pallor, and rapid, weak pulse
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When comparing angina with myocardial infarction (MI), which statement is true?
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Angina pain is relieved by rest and intake of nitroglycerin; pain of MI is not
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Calcium-channel blocking drugs are effective in:
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Reducing cardiac and smooth muscle contractions
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What is the cause of most cases of pyelonephritis?
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An ascending infection by E. coli
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Pyelonephritis may be distinguished from cystitis by the presence in pyelonephritis of:
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Urinary casts and flank pain
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The most common side effect of the thiazide diuretics is:
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Hypokalemia
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Which of the following is related to Wilms' tumor?
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Genetic defect
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Which of the following would result from obstruction of the left ureter by a renal calculus?
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An attack of renal colic
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Which of the following statements applies to bile salts?
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They emulsify lipids and lipid-soluble vitamins
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Why is cystitis more common in females?
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The urethra is short, wide and adjacent to areas with resident flora
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What would be the result of chronic bleeding from gastric carcinoma?
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Occult blood in the stool and anemia
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___________ is the involuntary discharge of urine and usually occurs at night.
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Enuresis
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Which of the following processes is likely to occur in the body after a meal?
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Glycogenisis
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What is a common cause of hiatal hernia?
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Increased intra-abdominal pressure