A and p – Flashcards
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Pituitary gland (hypophysis) location?
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In the sella turcica (hypophyseal fossa) of the skull. Suspended from the brain's hypothalamus by the infundibulum. Has anterior and posterior lobes.
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the "master gland"
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pituitary gland: secretes 9 hormones, and some of these hormones control other glands such as the thyroid gland, mammary gland, ovaries, testes & adrenal gland.
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The hypothalamus plays a critical role in
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a critical role in connecting the nervous system with the endocrine system.
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Antidiuretic Hormone (ADH)
-Secreted from where & function
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Posterior Pituitary Gland
-Causes reabsorption of extra water from the collecting ducts of the kidney's nephrons back into blood; urine production thus decreases.
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Adrenocorticotropic Hormone (ACTH)
-Secreted from where and function
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Anterior Pituitary Gland
-Stimulates cortex of adrenal gland to secrete its hormones.
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Hypothalamus function
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Regulates body temperature, hunger, thirst, and other autonomic control systems
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Infundibulum function
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a stalk that connects the pituitary gland to the hypothalamus
is the passage which pituitary hormones are delivered to the deeper parts of the brain
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Pituitary gland
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looksl ike a large pea and is attached to the end of the infundibulum; is controlled by the hypothalamus
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Pineal gland
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part of the epithalamus; a small endocrine gland taht secretes the hormone melatonin
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how does the release of cortisol from the adrenal cortex differ from the release of epinephrine (adrenalin) from the adrenal medulla,.
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Epinephrine (Adrenalin) and cortisol are hormones which are produced by the adrenal gland, , cortisol is produced by the cortex throughout the day of which the production increases in stressful situations.
adrenaline is produced by the medulla, Also while adrenalin is only produced during moments of high amount of stress or excitement
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how does the relaionship of the anterior pituitary to the hypothalamus differ from the posterior pituitary of the hypothalamus?
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•The anterior pituitary secrete protein hormones. •The posterior pituitary extension of the hypothalamus. It is composed largely of the axons of hypothalamic neurons which extend downward as a large bundle behind the anterior pituitary
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Which of the following statements is true for the nervous system but NOT the endocrine system?
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There is a special anatomical arrangement between the secretory cell and the target cell.
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A secondary endocrine organ is ________.
a) an organ that secretes at least two hormones
b) an organ that receives communication from at least two hormones
c) an organ that secretes tropic hormones
d) an organ that is the target of tropic hormones
e) an organ that secretes hormones, but is better known for another function
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an organ that secretes hormones, but is better known for another function
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Secretion of hormones from the anterior pituitary is stimulated by ________ released from the ________.
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releasing hormones : hypothalamus
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A person has a tumor in the hypothalamus causing an excess in TRH secretion. Which of the following correctly describes changes in plasma levels of hormones?
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increased TRH, increased TSH, and increased thyroid hormones
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The hypothalamus is connected to the posterior pituitary by the hypothalamic-pituitary portal system.
a) true
b) false
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false
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A patient has a goiter associated with high plasma levels of both thyrotropin releasing hormone (TRH) and thyroid stimulating hormone (TSH). Her heart rate is elevated. This patient likely has which of the following?
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hypothalamic tumor secreting large amounts of TRH
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In order to maintain a positive energy balance, the body must ________.
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consume more energy than it expends
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Which of the following stimuli does NOT stimulate insulin secretion?
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increased epinephrine
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Which of the following is NOT an action of insulin?
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synthesis of fatty acids in skeletal muscle
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The release of glucagon during the absorptive state by certain amino acids in a high-protein meal would facilitate the ________.
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maintenance of blood glucose in a low-glucose meal
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The most abundant form of thyroid hormone secreted into the blood is ________; the most active form at the target cell is ________; and the form that provides the strongest negative feedback is ________.
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T4 : T3 : T4
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The release of T3 and T4 occurs through ________, and it can bind to ________ to be transported through the bloodstream.
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diffusion : albumin
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Which of the following is NOT one of the actions of thyroid hormone?
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enhance parasympathetic nervous activity
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A patient has Addison's disease due to destruction of the adrenal cortex. Which of the following symptoms is the patient likely to exhibit?
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Hypoglycemia, poor tolerance for stress, elevated plasma potassium levels and cardiac arrhythmias
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The ________ ensure(s) that blood levels of a specific releasing hormone are locally high in order to stimulate the pituitary
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d) hypothalamic-pituitary portal system
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What hormone is secreted by the heart?
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atrial natriuretic peptide
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A person has a tumor in the hypothalamus causing constant low levels of TRH secretion. Which of the following correctly describes changes in plasma levels of hormones?
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decreased TRH, decreased TSH, and decreased thyroid hormones
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in order to lose weight, a person must be ________.
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in a state of negative energy balance
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Any excess glucose in the liver that is not required for energy and not stored as glycogen will ________.
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be converted into fatty acids
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The metabolic adjustments that occur in the body during the switch from absorptive to postabsorptive state are largely triggered by increases in ________ concentration.
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glucagon
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What is the primary hormone mediating the stress response?
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cortisol
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Which of the following hormones decrease lipolysis?
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insulin
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Stimulates insertion of GLUT-4 transporters into cells of the body.
28) This hormone is released in response to activation of the sympathetic nervous system and binds to adrenergic receptors on effector cells
29) This hormone is secreted from the pancreas during the
postabsorptive state.
30) A person with an excess of this hormone would tend to have a
high metabolic rate.
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d)insulin
e)epinephrine
c)glucagon
a) thyroid hormones
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What happens to glucose during the postabsorptive state?
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Glucose is synthesized by gluconeogenesis and glycolysis and is spared for use by the nervous system.
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Which of the following is a correct example of short-loop negative feedback?
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TSH inhibits the release of TRH
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Which of the following statements about antidiuretic hormone is true?
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It has opposite effects on urine and plasma osmolarity
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patient has a smaller than normal thyroid gland, high plasma levels T4, and low plasma levels of thyroid-stimulating hormone (TSH). Which of the following is the most likely explanation for these findings?
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The patient is taking thyroid extract
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Insulin stimulates the uptake of glucose by ________.
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causing GLUTs to be incorporated into the plasma membrane of some cells
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Glucagon is secreted from ________ cells of the pancreas and stimulates
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alpha : catabolism
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Which of the following will NOT occur as a consequence of the release of epinephrine?
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a) increased release of amino acid
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Which of the following is NOT one of the actions of thyroid hormone?
a) calorigenesis
b) enhance parasympathetic nervous activity
c) energy mobilization
d) promote synthesis of beta adrenergic receptors
e) gluconeogenesis.
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benhance parasympathetic nervous activity
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What is the primary hormone mediating the stress response?
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e) cortisol
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Glucagon
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d) pancreas
e) adrenal cortex
a) posterior pituitary
b) adrenal medulla
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Which of the following increases the release of glucagon?
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decreased blood glucose, increased sympathetic activity, and increased blood amino acids
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Insulin stimulates the cellular uptake of glucose by ________.
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a) causing GLUTs to be incorporated into the plasma membrane of some cells
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Insulin is secreted by the ________ cells of the pancreas and stimulates ________.
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beta : anabolism
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Oxytocin is synthesized in the ________ nucleus located within the ________.
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supraoptic : hypothalamus
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The hypothalamic regulator of cortisol secretion is ________.
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e) corticotropin releasing hormone
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Which of the following statements is not true of the endocrine system?
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a ) It is one of two major regulatory systems of the body
b) It is composed of glands that secrete chemical messengers into the blood
c) It is an important regulator of homeostatic mechanisms
d) It influences and is influenced by the nervous system
e) All of the choices are true
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An endocrine cell that contains an abundance of granular endoplasmic reticulum, a large Golgi apparatus, and secretion granules is likely to
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Secrete a peptide/protein hormone and secrete by exocytosis
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The concentration of a hormone in plasma is determined by
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Its secretion and clearance rates and whether or not it binds to carriers and/or other plasma proteins
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Some hormones are transported in plasma bound to proteins. These proteins function to
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a) Maintain a stable high concentration of the hormone in the plasma and reduce its clearance rate from plasma
b) Reduce the binding of the hormone to its receptors in some cases
c) Make the hormone more soluble in aqueous plasma
d) Do all of these things
e) Do none of these things
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Receptors for steroid hormones
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a) Are proteins in the nucleus and/or cytoplasm
b) Undergo allosteric modulation when they bind to the hormone
c) Regulate gene transcription
d) Both are proteins in the nucleus and/or cytoplasm and regulate gene transcription are correct
e) All of the choices are correct
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In the absence of thyroid hormone, epinephrine stimulates release of a small amount of fatty acids from adipose cells. In the presence of thyroid hormone (which has no effect by itself), epinephrine causes a much more substantial release of fatty acids from the cells. The effect of thyroid hormone on epinephrine's actions is called
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Permissive
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Secretion of hormones is controlled by
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a) Concentration of mineral ions in the blood
b) Neural input
c) Tropic hormones
d) Concentration of mineral ions in the blood and tropic hormones
e) All of these things
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The median eminence of the hypothalamus is
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e) A site of neurohormone release into blood vessels and a major link connecting the nervous and endocrine systems
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Which of the following hormones is not secreted by the anterior pituitary gland?
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Erythropoietin
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Brain hormones that regulate the secretion of hormones from the anterior pituitary gland are called
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Hypophysiotropic hormones and releasing or release-inhibiting hormones
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Hypertrophy of the adrenal cortex could result from
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a) Excessively rapid clearance of cortisol from the circulation
b) A tumor of the pituitary gland that secretes excessive amounts of ACTH
c) Inactivation of enzymes that are required to synthesize corticosteroids
d) Excessively rapid clearance of cortisol from the circulation and a tumor of the pituitary gland that secretes excessive amounts of ACTH
e) All of the choices are correct
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Exposure to stress activates the hypothalamo-pituitary-adrenocortical system as demonstrated by
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Increased secretion of corticotropin from the anterior pituitary in response to stress and increased secretion of corticotropin releasing hormone from the hypothalamus in response to stress
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If the pituitary gland is removed from a human subject, which of the following is likely to occur?
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The adrenal gland will atrophy and plasma cortisol levels will be reduced
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The hormones secreted by the posterior pituitary include
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Vasopressin and oxytocin
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Thyroid hormones stimulate metabolism by stimulating
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The Na/K ATPase
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Which of the following is/are not stimulated by cortisol during stress?
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Glucose uptake
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Which of the following statements regarding activation of the sympathetic nervous system during stress is true?
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It increases one's ability to respond to situations where physical activity is required
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an endocrine cell that contains an abundance of granular endoplasmic reticulum, a large Golgi apparatus, and secretion granules is likely to secrete a peptide hormone.
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a) True
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Steroid hormones are stored in the cells that synthesize them until a stimulus is received that provokes their secretion.
a) True
b) False
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b) False
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The adrenal cortex secretes androgens.
a) True
b) False
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True
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Thyroid hormones exert a permissive effect on the actions of epinephrine.
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True
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Stimuli for the secretion of hormones include changes in plasma concentrations of ions, nutrients, and other hormones.
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True
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The adrenal cortex is part of the autonomic nervous system.
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b) False
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Hormones of the posterior lobe of the pituitary are synthesized in neuronal cell bodies of the hypothalamus and transported to the pituitary in axonal fluid.
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a) True
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The pituitary portal circulation refers to the blood vessels linking the anterior pituitary with the target glands of anterior pituitary hormones
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b) False
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The effect of some tropic hormones is to stimulate release of other tropic hormones.
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a) True