Micro Exam 4 (final) – Flashcards

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The first antibiotic discovered was

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penicillin

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The antibiotic streptomycin binds with  tRNAmet at the 30S ribosome.  For this information you can conclude that streptomycin
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prevents transcription in prokaryotes
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In the presence of penicillin, what kills the bacteria?

 

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it undergoes osmotic lyses
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 Chloramphenicol

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interferes with protein synthesis in microorganisms
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Tetracycline is the drug of choice in treating most

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Rickettsial infections
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Penicillin G is most effective against

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log phase gram-positive bacteria
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Tetracycline antibiotics interfere with 

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protein synthesis
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Cephalosporins act by 

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interfering with cell-wall biosynthesis
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Amoxicillin is preferable to penicillin because it

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is absorbed more easily from the intestines when taken orally
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The beta-lactam nucleus is the basic structure of the 

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penicillins
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In competitive inhibition, sulfanilamide is used by a bacterium in an abortive attempt to 

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form folic acid
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Isoniazid is of particular value 

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for treating tuberculosis
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All aminoglycoside antibiotics function by 

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attaching irreversibly to ribosome and preventing protein synthesis 
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Members of the genus Streptomyces

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produce many well-known antibiotics
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Both the cephalosporin and penicillin antibiotics

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act on the cell wall of bacteria
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Which of the following antibiotics is not bactericidal?

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Aminoglycosides

 

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Chloroquine, primaquine, and quinine are of value for the treatment of

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cases of malaria
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What is the action of the antibiotic rifampin?

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inhibiting RNA synthesis
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Use of antibiotics in animal feed leads to antibiotic- resistant bacteria because

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the antibiotics kill susceptible bacteria, but the few that are naturally resistant live and reproduce, and their progeny repopulate the host animal  

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What is the alternative drug used in treating syphilis and gonorrhea infection in penicillin sensitive patient? 

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tetracycline
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Which antibiotics do not inhibit cell wall biosynthesis? 

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neomycin
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A common feature of bacitracin and polymyxin B is that both antibiotics

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are produced by Bacillus species
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What is the action of macrolides like erythromycin?

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inhibiting protein synthesis
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Which antibiotic is not given to pregnant women because is stunts fetus bone growth? 

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tetracycline
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All the following apply to the tetracycline antibiotics except

A.  they are associated with discoloration of the teeth.

B.  they are used for rickettsial and chlamydial diseases.

C.  they are broad-spectrum antibiotics.

D. they may cause aplastic anemia or the gray syndrome

 

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they may cause aplastic anemia or the gray syndrome
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A virion is 

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a complete infection virus particle
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The definition of lysogeny is 

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phage DNA is incorporated into host cell's chromosome
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A clearing due to phage replication on a confluent "lawn" of bacteria is called a;

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plaque
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Cytopathic effects are changes in host cells due to;

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viral infections
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All viruses possess

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a genome and capsid
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A bacteriophage is a type of virus that;

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replicates within bacteria
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The togaviridae cause equine encephalitis and other diseases.; These RNA viruses have a symmetrical capsid with 20 equilateral triangles and 20 edges and 12 points.; Such a capsid is an example of a(n);

;

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isohedral capsid
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Describes a method by which an envelope virus leaves the host cell while acquiring an envelope

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budding
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Latent animal viruses are present in cells as;

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proviruses
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The following steps occur during multiplications of the DNA virus like Herpes viruses.; What is the third step?

A.; Attachment

B. Biosynthesis

C. ;Penetration

D.; Release

E.; Uncoating

;

;

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biosynthesis
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Viral envelopes are usually acquired by;

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bidding through the membrane of the cell
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;

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neuramindase of influenza viruses assists in;

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release of virus through the cell membrane
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Animal viruses have attachment sites

;

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over the entire surface of the capsid
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;

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The retrovirus can synthesize DNA from RNA because it contains

;

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the enzyme reverse transcriptase
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The viruses of influenza, measles and mumps are know for their ability to;

;

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clump red blood cells
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;

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The nucleic acid of a virus encased in its protein coat is often referred to as the;

;

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nucleocapsid
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;

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Yellow fever is a viral disease of the liver.; As such, the yellow fever virus is classified as a

;

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viscerotropic virus
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You have isolated an animal virus whose capsid is a tightly wound coil resembling a corkscrew or spring.; Such a capsid is referred to as a(n)

;

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helix
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Rous sarcoma virus causes a cancer in chickens.; This is a(n) ________ virus, which is classified in the _______ because it contains reverse transcriptase.;
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RNA, retroviridae
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The rabies virus is a(n) __________ virus, which is classified in the ________ group. ;

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RNA, rhabdoviridae
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;

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All the following are possible methods for cultivating viruses except

A.; fertilized chicken eggs.

B.; tissue cultures.

C.; laboratory animals.

D. blood agar medium

;

;

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D. blood agar medium
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Which of the following is true of the influenza virus?

A.; The virion has no envelope.

B. The virion undergoes antigenic variations

C.; The virion has no protein associated with it.

D.; Replication of the virion takes place in the body's liver cells. 

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the virion undergoes antigenic variations
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The respiratory synctial virus takes its name from the 

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a formation of giant cells in the tissue formation cells
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Viruses that have spikes on their envelopes and contain both hemagglutinin and neuraminidase cause

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influenza
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The fluid-filled vesicles occurring in cases of chickenpox contain

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large amounts of viruses
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An 8-year-old female has scabs and pus-filled vesicles on her face and throat.  Three weeks earlier she had visited her grandmother who had shingles.  What infection does the 8-year-old have? 
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chickenpox
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When is Respiratory Syncytial Virus (RSV) more commonly seen?
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in most children under the age of 5
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SARS is caused by a

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corona virus
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The etiologic agent of warts is

 

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Papillomavirus
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Which one of the following is not a dermotropic viral disease?

A.  Chickenpox

B.  Mumps

C. SARS

D.  Rubella

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SARS
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The etiologic agent of fever blisters

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Herpes simplex
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.  How can herpes simplex HSV-1 be prevented?

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dont kiss someone who has a cold sore
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German measles is similar to measles because

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a skin rash occurs in both diseases
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Herpes zoster, or shingles, is an adult disease caused by 

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the same virus that causes chickenpox
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Most cases of herpes zoster, or shingles, occur in

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people over 50 years of age
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The MMR immunization program has significantly affected the annual incidence of all the following diseases except

A.  rubella

B.  German measles

C.  mumps

D.  measles

E. chickenpox  

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chickenpox
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A large, brick-shaped DNA virion is the responsible agent of 

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smallpox
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 The prospect for developing a vaccine for the common cold are not promising because

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many different viruses can cause the common cold
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  All the following characteristics apply to rhinoviruses except

A. they are DNA viruses with helical symmetry

B.  the belong to the Picornaviridae family of viruses.

C.  that take their name from the Greek rhinos meaning nose.

D.  they can cause head colds.

E.  they can be transmitted by hand-to-hand contact.  

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they are DNA viruses with helical symmetry
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The scientific name for measles is

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rubeola
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Each of the following diseases is caused by a member of the herpesviridae, except

A.  chickenpox

B.  shingles

C. smallpox

D.  cold sores

 

 

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smallpox
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All the following statements are associated with parainfluenza except:

A.  the parainfluenza virus is an RNA virus

B.  this is a disease associated with summer weather

C.  parainfluenza is generally a milder disease than influenza

D. parainfluenza is most often seen in children over the age of 6

 

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parainfluenza is most often seen in children over the age of 6
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The rotavirus and echovirus are both associated with

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gastrointestinal distress
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Yellow fever is so-named because

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it is accompanied by substantial jaundice 
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The adjectives western equine, La Cross, and California all apply to 

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forms of arboviral encephalitis 
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Vaccine are available for all of the following diseases, except

A.  yellow fever

B.  rabies

C. mononucleosis

D.  polio

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mononucleosis
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Infectious mononucleosis is caused by Epstein-Barr virus.  Another condition caused by this virus is 

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Burkett's Lymphoma
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If a woman has hepatitis B receive from an emergency blood transfusion, which of the following types of virus will be present?;

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a DNA virus
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Liver inflammation is a principal symptom of a disease transmitted by contaminated food and water as well as by contact, arthropods, and sexual intercourse.; This disease is;

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hepatitis A
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A woman with a fluctuating fever comes to a physician. She says that every bone in her body feels like it's breaking. Of the following, the patient is likely to be suffering from

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dengue fever
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All hepatitis infections are commonly associated with

 

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liver infections
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The Sabin polio vaccine consists of viruses inactivated with formaldehyde, whereas the Salk vaccine is made with attenuated viruses.

true or false?

 

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false
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Lassa fever and Marburg disease are typical of the viral diseases that affect the skin and cause severe pocklike lesions to form. 

true or false?

 

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false
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Ebola hemorrhagic fever is associated with a filovirus.

true or false?

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true
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A typical zoonosis

 

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rabies
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Symptoms for this hemorrhagic fever are fever, headache, joint and muscle aches, sore throat, and weakness. This followed by diarrhea, vomiting, and stomach pain. A rash, red eyes, hiccups and internal and external bleeding may be seen in some patients. What is this disease?

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ebola
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The virus of hepatitis A is

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very resistant to physical and chemical agents
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Once the symptoms have fully materialized in an individual, rabies has

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one of the highest mortality rates of any human disease
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The reason hepatitis C infections are often misdiagnosed is because

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symptoms develop slowly
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Rubor, calor, tumor and dolar are

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four characteristic signs of inflammation 
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All the following may be effects of complement activation except

A.  lysis of the cell through cytoplasmic leakage.

B.  attraction of phagocytes

C.  contraction of smooth muscles through histamine release

D. enhanced T-lymphocyte activity through thymus gland interaction

E.  formation of an attack complex. 

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enhanced T-lymphocyte activity through thymus gland interaction
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Which of the following exhibits the highest phagocytic activity in the blood?

A.  Neutrophils

B.  Erythocyytes

C.  Lymphocytes

D. Basophils

E.  Eosinophils

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neutrophils
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Normal microbiota provide protection from infection by 

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out-competing newcomers
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Chill is a sign that the body temperature is 
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rising
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The classical pathway for complement activation is initiated by 

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antigen-antibody reactions
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Macrophages arise from these. 

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lymphocytes
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A nonspecific resistance factor effective against viral infection is 

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interferon
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Which of the following is the best definition for innate immunity?

A.  resistance is a response to a particular microbe

B.  a response that is directed only against a particular microbe

C.  a system that protects us against trauma and disease

D. several nonspecific diseases present in all humans from the time of birth

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several nonspecific diseases present in all humans from the time of birth
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Neutrophils are those leukocytes that function
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as phagocytes in body resistance
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The link between macrophages and neutrophils is that both cells

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are phagocytes
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A nonspecific leukocyte effective against viral infection is

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NK cell
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Which of the following leukocytes are involved in acquired immunity?

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monocytes and macrophages
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Opsonins may be described as

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antibodies that enhance the efficiency of phagocytosis
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Natural killer (NK) cells can be describe by all of the following except

A.  NK cells have special receptors on the surface of their membrane.

B.  NK cells recognize the body’s cells and do not attack them.

C.  NK cells bind to the target cell and induce lysis.

D. NK cells rely on class II MHC proteins to separate normal cells from target cells

 

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NK cells rely on class II MHC proteins to separate normal cells from target cells
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 NK cells secrete two enzymes that attack foreign, virus infected or cancerous cells. What are they?

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perforin and granzymes
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All of the following statements are true about the complement except

A.  complement is a series of 15 proteins circulating in the lymphatic system.

B.  complement works in a nonspecific manner.

C.  C3 molecules activate other complement components

D.  complement components interact with phagocytes.

 

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complement is a series of 15 proteins circulating in the lymphatic system.
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The innate immune system recognizes pathogens by identifying unique microbial molecular sequences not found on host cells. This system of recognition is called  

 

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PAMP
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