USMLE Step 2CS Differential for Cases by Kaplan – Flashcards

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1. Ankle Pain
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Fracture, Ligament Injury, Infection, Gout/Psuedogout
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2. Back
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MSK, Infection, Tumor, Kidneys, Lungs, Abdominal Organs
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3. Sore throat
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Pharyngitis (Strep v Mono), URI, Epiglottitis, Abcess
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5. Left Arm Weakness
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Stroke, Radiculopathy, Thoracic Outlet, MSK
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10. 40 yo vaginal bleeding
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menstruation, DUB, ectopic, miscarriage, infections, endo cancer
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11. 60 yo vaginal bleeding
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endometrial cancer, atrophic vaginitis, cervical polyps, rectal or urinary bleeding
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13. HTN
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Heart Failure, CAD, Stroke, Kidney Failure, PVD, Retinopathy
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18. Adolescent Weight Loss
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Depression, Anorexia, Hyperthyroidism, Drugs, Diabetes, Cancer
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20. Pediatric Bed Wetting
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Recent Stressors, UTI, Constipation, Diabetes
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21. Pediatric SOB
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Pulmonary (Asthma, Croup, Pneumonia), Cardiac, Anemia
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22. Old Person Check Up
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CVD (Chest Pain, SOB, Orthopnea), Cancers (Eso, Lung, Colon, Breast/Prostate, Skin)
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24. Crying Baby
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Colic, Ear Infection, GI Infection, MSK Injury
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25. Mental Status Change in an Old Person
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Alzheimers, Depression, Stroke, Infection, Drugs
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26. Diabetes Check Up
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Diabetes, Retinopathy, CAD, CKD, PVD, Neuropathy/Ulcers
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28. Child with Vom & Diarrhea
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Infection (Bacterial, Viral, Parasitic), Medications, Allergies, Dehydration
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30. Obesity
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Diet/Exercise, Eating D/O, PCOS, Thyroid Dz
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35. Temper Tantrum
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Seizures, Arrythmia, Cyanosis, Self-harm, Punishment
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38. Diarrhea
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Infection (Travel, Pets, Sick Contacts), Medication, IBD, IBS, Pancreatic Dz
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40. Hearing Loss
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Sensoryneural, Conductive, Infection, Tumor, Medications
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Bandlike headache- bilat lasts for hours or days recurrent constant, not throbbing better with massage normal vital signs, normal neuro
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tension headache
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unilateral throbing headache photophobia sonophobia aura recurrent no fever, no weakness in extremities
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classic migraine
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throbbing, one-sided headache fevers jaw pain visual changes tender over temporal artery age over 50
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temoporal arteritis
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recent upper resp infection pain in cheek below eye dull, constant ache, worse leaning over nasal discharge nad stuffiness tenderness to palpation of maxillary sinus no weakness in extremities
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sinusitis
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pain centered over eye first episode red eye decreased visual acuity dilated pupil
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glaucoma (closed angle)
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hx of trauma on warfarin headache mental status changes ataxia focal weakness visual changes
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subdural hematoma
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unilateral sudden and intense headache pain behind eye lasts a couple hrs each day and gone recurrent time of day lacrimation blushing of face
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cluster headache
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headache syncope very severe intensity first episode vomiting mental status changes stiff neck
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subarachnoid bleed
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heavy substernal pressure feeling SOB Nausea diaphoresis lasts minutes to starting couple hours ago Diaphoretic abnormal vital signs no high fever
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acute coronary syndrome
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pleuritic chest pain sob unilateral swollen lower leg hx of DvT in past not on warfarin tachycardia tachypnea no pain to palpation of chest wall unilateral swollen leg
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pulmonary embolism
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pleuritic chest pain cough sputum production fever dullness to percussion abnormal breath sounds increased tactile fremitus
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PNA
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pleuritic unilateral chest pain sudden onset SOB increased HR increased RR Decreased unilateral breath sounds Decreased tactile fremitus
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Pneumothorax
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Ripping chest pain sudden onset pain may migrate to neck or back blood pressure difference between arms heart murmur (if aortic insufficiency) pulse differences between sides
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aortic dissection
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pain better sitting up and leaning forward. pleuritic started after viral URI Cardiac rub fever
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pericarditis
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sharp pain hurts with mvt and twisting point tenderness causing pain in chest
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costochondritis
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unilateral pain paresthesia of skin unilateral dermatome unilateral blistering rash on a dermatome fever
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herpes zoster
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heartburn sour taste coming up to mouth pregnant better with antacids no fever no pleuritic pain no abdominal pain
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esophageal reflux
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dyspnea on exertion pedal edema orthopnea hx of HTN, smoking, coronary disease rales in lungs gallop heart rhythm distended neck vein distneded liver
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heart failure
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dyspnea cough weight loss pursed lip breathing chronic condition, smoking hx tachypnea increased chest AP diameter clubbing of fingers decreased air entry prolonged expiratory phase
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COPD
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Recurrent attacks of dyspnea cough wheezing hx of asthma wheezing
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asthma
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fatigue generalized weakness pallor
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anemia
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sudden onset change in voice choked on food or denture stridor cyanosis
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airway obstruction
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substernal chest pain dyspnea nausea hx of smoking HTN Diaphoresis (list any abnormal vital signs)
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myocardial infarction
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acute shortness of breath wheezing hx of exposure to allergen hives hypotension tachypnea tachycardia
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anaphylaxis
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RUQ pain- intermittent can last several hours occurs after fatty meal no fever tender right upper quadrant
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biliary colic
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RUQ pain radiates to R scapula FEver + murphy's sign tender right upper quadrant
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cholecystitis
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epigastric RUQ pain taking aspirin or NSAIDs blood in stool pain may radiate to back epigastric and RUQ tenderness
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peptic ulcer disease
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epigastric and RUQ pain hx of alcoholism hx of gallstone epigastric and RUQ tenderness
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pancreatitis
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fever jaundice RUQ pain behavior that leads to hep virus exposure Jaundice tender enlarged liver - Murphy fever
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Hepatitis
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midabdominal pain migrating to RLQ anorexia feverish acute onset RLQ tenderness +obturator sign + psoas sign fever
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appendicitis
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LLQ pain fever diarrhea often vomiting fever LLQ tenderness
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diverticulitis
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Fever lower abd pain vaginal discharge sexually active fever low abd tenderness +pain with cervical motion tenderness shuffling gait
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Pelvic inflammatory disease
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lower abd pain may radiate to top of shoulder late period or known pregnant lower abd tenderness
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Ectopic pregnancy
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sudden onset unilateral lower pain nausea and vomiting can start with exercise lower abd tenderness
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ovarian torsion
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bright red blood streaks usually on stool or toilet paper hx of patient able to palpate hemorrhoid no abd tenderness no fever
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hemorrhoid
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pain with defacation bright red blood with straining at stool no fever no abd tenderness
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anal fissure
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abd cramps blood mixed with stool may be recurrent age > 40 pallor
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diverticulosis
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diarrhea prominent bloody stool vomiting others with same illness acute onset fever diffuse abd tenderness no rebound
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infectious diarrhea
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fever diarrhea chronic onset positive family history fever diffuse abd tenderness
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inflammatory bowel disease
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emotional, stressful situation quick recovery in minutes no seizure activity normal vital signs (when recovered)
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vasovagal
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palpations chest discomfort shortness of breath medication history abn heart rate irregular heartbeat
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arrhythmia
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alcohol ingestion medication as cause dehydration tachycardia hypotension when standing advanced age
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orthostatic hypotension
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shortness of breath anginal chest discomfort family history of same age 60 and up narrow pulse pressure displaced PMI
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aortic stenosis
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palpitations dizziness shortness of breath younger athlete family history occurs with exercise heart murmur
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hypertrophic cardiomyopathy
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previous arthritis of the knee red, swollen, tender calf swelling and fullness behind knee
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baker cyst rupture
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red, swollen, tender calf distal break in skin of leg fever inguinal adenopathy
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cellulitis
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chronic leg swelling chronic skin changes not red or tender no fever inguinal adenopathy lower abd mass
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lymphatic obstruction
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pain and swelling recently in leg risk factor for hypercoagulable state lower leg red, warm, swollen, tender
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DVT
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dyspnea on exertion pedal edema orthopnea hx of HTN, smoking, coronary disease rales in lungs gallop heart rhythm distended neck vein distended liver
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heart failure
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foamy urine weight gain edema also around face fatigue edema bilaterally
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nephrotic syndrome
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jaundice fatigue right upper quadrant pain jaundice ascites right upper quadrant tenderness mental status changes edema bilaterally
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liver failure
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pain, cramp, paresthesia in legs elevated bmi red legs and ankles with skin changes bilateral edema
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obesity/venous insufficiency
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temporal history of medications followed by vomiting no blood in emesis vomiting no fever abdomen soft, nontender
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medications (chemotherapy, general anesthesia, opioids)
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may be other people also sick abd cramps and pain diarrhea possible vomiting possible fever abd tenderness
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GI- rotavirus, norovirus, food poisoning, campylobacter
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hx of occurring on boat, moving car vertigo vomiting possible nystagmus
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vestibular system (motion sickness, benign paroxysmal vertigo)
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headache scotoma (for migraine) vomiting may have unilateral weakness mental status changes
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CNS migraine mass lesion bleeding arterovenous malformation seizure trauma pseudotumor cerebri
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vomiting possible blood in emesis anorexia fever abd tenderness possible rebound
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vomiting from abd organs appendicitis cholecystitis acute hepatitis peptic ulcer bowel obstruction torsion of gonads
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weakness fatigue dehydration darkening of skin vomiting dry mucous membranes
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endocrine and toxins (alcohol DKA)
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vomiting chest pain back pain SOB increased resp rate heart murmur unequal pulse
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acute cardiovascular illness Myocardial infarction pulmonary embolism aortic dissection
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