Home Page Flashcards Dave's: Nuclear Medicine Board Review 15 - Flashcards

Dave’s: Nuclear Medicine Board Review 15 – Flashcards

Deloris Connelly

7 July 2022

Unlock all answers in this set

Unlock answers

question

Indium 111 WBC scan

Indium 111 WBC scan

answer

Dose: 500 uCi Indium-111

question

Indium 111 WBC scan

Indium 111 WBC scan

answer

T1/2: 2.8 (3) days

question

Indium 111 WBC scan

Indium 111 WBC scan

answer

Photopeaks: 173 and 247 keV (20% windows)

question

Indium 111 WBC scan

Indium 111 WBC scan

answer

Imaging: planar +/- spect at ?4, 24, ?48 hr

question

Indium 111 WBC scan

Indium 111 WBC scan

answer

Critical organ: spleen 20 rads/500 uCi

question

I-123

I-123

answer

Surveillance of thyroid CA - thyroid hormone withdrawl vs Thyrogen

question

I-123

I-123

answer

Dose: 2-4 mCi Orally

question

I-123

I-123

answer

Energy: 159 keV. T1/2 = 13 hrs.

question

I-123

I-123

answer

Image: 24 hr +/- 48 hr planar WB + Hi-count neck/chest. ? Cobalt transmission

question

I-123

I-123

answer

Critical Organ: bladder

question

I-131

I-131

answer

Treatment & surveillance of thyroid CA

question

I-131

I-131

answer

D/c thyroid hormone vs thyrogen

question

I-131

I-131

answer

Dose: 4 mCi I-131 PO.

question

I-131

I-131

answer

T1/2 = 8 days.

question

I-131

I-131

answer

Energy: multiple, but image 364 keV

question

I-131

I-131

answer

Imaging: 48 hr planar WB + Hi-count neck/chest. ? Delayed images.

question

In-111 Octreoscan (pentetreotide)

In-111 Octreoscan (pentetreotide)

answer

Indications: Carcinoid, insulinoma, gastrinoma, glucagonoma, pheochromocytoma, paraganglionoma, medullary thyroid cancer, VIPoma, pituitary adenoma

question

In-111 Octreoscan (pentetreotide)

In-111 Octreoscan (pentetreotide)

answer

Dose: 5 mCi Indium-111 pentetreotide IV

question

In-111 Octreoscan (pentetreotide)

In-111 Octreoscan (pentetreotide)

answer

Energy: 173 & 247 keV, 20% photopeaks

question

In-111 Octreoscan (pentetreotide)

In-111 Octreoscan (pentetreotide)

answer

T ½ = 2.8 (3) days

question

In-111 Octreoscan (pentetreotide)

In-111 Octreoscan (pentetreotide)

answer

Patient Prep: good hydration and bowel prep. D/c octreotide 1 wk prior. (Octreotide immediate-release injection is also used to control diarrhea and flushing caused by carcinoid tumors (slow-growing tumors that release natural substances that can cause symptoms) and vasoactive intestinal peptide secreting adenomas (VIP-omas; tumors that form in the pancreas and release natural substances that can cause symptoms).

question

In-111 Octreoscan (pentetreotide)

In-111 Octreoscan (pentetreotide)

answer

Imaging: 24 +/- 48 hrs WB planar +/- spect with fusion.

question

In-111 Octreoscan (pentetreotide)

In-111 Octreoscan (pentetreotide)

answer

Critical Organ: kidney 1.8 rads/mCi, bladder 1.0 rads/mCi.

question

I-123 MIBG - Adrenomedullary Imaging

I-123 MIBG - Adrenomedullary Imaging

answer

Indications: pheochromocytoma, paraganglionoma, neuroblastoma.

question

I-123 MIBG - Adrenomedullary Imaging

I-123 MIBG - Adrenomedullary Imaging

answer

I-123: 159 keV

question

I-123 MIBG - Adrenomedullary Imaging

I-123 MIBG - Adrenomedullary Imaging

answer

13 hr T ½

question

I-123 MIBG - Adrenomedullary Imaging

I-123 MIBG - Adrenomedullary Imaging

answer

Dose: 10 mCi I-123 MIBG IV

question

I-123 MIBG - Adrenomedullary Imaging

I-123 MIBG - Adrenomedullary Imaging

answer

Imaging: Whole body planar +/- hi-count planar vs spect with fusion at 24 hrs, =/- 48 hrs.

question

I-123 MIBG - Adrenomedullary Imaging

I-123 MIBG - Adrenomedullary Imaging

answer

Protect the "critical organ" - the thyroid. Pretreat with Lugol's soln (6.3 mg I/drop). 1 gtt 2x/d for 1 day prior and 7 days post.

question

F-18 FDG

F-18 FDG

answer

Energy: 511 keV, coincident photons

question

F-18 FDG

F-18 FDG

answer

T 1/2: 109 min

question

F-18 FDG

F-18 FDG

answer

Dose: 10-20 mCi

question

F-18 FDG

F-18 FDG

answer

Imaging - PET/CT at 60 min post-injection, +/- delays in H;N, others.

question

GALLIUM-67

GALLIUM-67

answer

Indications: Tumor imaging, infection and inflammation imaging.

question

GALLIUM-67

GALLIUM-67

answer

Energy: 93, 185, 288, 394 keV (Think 100, 200, 300, 400 keV.)

question

GALLIUM-67

GALLIUM-67

answer

T ½ 78 hrs.

question

GALLIUM-67

GALLIUM-67

answer

Dose: 10 mCi.

question

GALLIUM-67

GALLIUM-67

answer

Critical Organ: Bone Marrow 0.6 rads/mCi

question

Quality Control of Radiopharmaceuticals

answer

Chemical purity Radiochemical purity Radionuclide purity

question

Causes of diffuse liver uptake on bone scan

Causes of diffuse liver uptake on bone scan

answer

Aluminum contamination (chemical purity) Colloid formation (radiochemical purity)

question

Chemical purity

Chemical purity

answer

Mostly refers to amount of aluminum contamination

question

Chemical purity

Chemical purity

answer

Legal limit of aluminum is 10 micrograms/ml

question

Radiochemical purity

Radiochemical purity

answer

Refers to the Tc based compounds other than the desired pharmaceutical ;TcO4 TcSC Other Tc Tc DMSA Tc HMPAO

question

Radiochemical purity

Radiochemical purity

answer

Tested with thin layer chromatography: free Tc04 migrates in saline and methanol Tc99m compounds migrate in saline only

question

Radionuclide purity

answer

Refers to molybdenum breakthrough

question

Radionuclide purity

answer

Test is based on greater energy of Moly HVL in lead is 6mm vs. 0.2 mm for Tc

question

Radionuclide purity

answer

Legal limit is 0.15 uCi Mo/mCi Tc

question

Radionuclide purity

answer

If there is too much moly then the dose to the patient especially the liver is increased Mo has a long t 1/2 and is a Beta emitter

question

Bone Scan Tc-99m MDP

Bone Scan Tc-99m MDP

answer

Energy: 140 keV

question

Bone Scan Tc-99m MDP

Bone Scan Tc-99m MDP

answer

T1/2: 6 hrs

question

Bone Scan Tc-99m MDP

Bone Scan Tc-99m MDP

answer

Dose: 25 mCi

question

Bone Scan Tc-99m MDP

Bone Scan Tc-99m MDP

answer

Normal biodistribution: bone, kidney, bladder

question

Bone Scan Tc-99m MDP

Bone Scan Tc-99m MDP

answer

Critical organ=bladder (2-8 rads)

question

Bone Scan Tc-99m MDP

Bone Scan Tc-99m MDP

answer

Timing: 2 hrs

Get an explanation on any task

Get unstuck with the help of our AI assistant in seconds

New