Skin cancer and ABCDE rule – Flashcards

Most common form of skin cancer. BCC appears as a PEARLY or WAXY skin lesion with an ULCERATED center that DOES NOT HEAL. Color: white, light pink, brown, or flesh colored.

Rough, scaly patches. May be tender on palpation. Prolonged sun exposure leads to damage of keratinocytes. This is a precancerous precursors to squamous cell carcinoma.

Derived from the epithelium of hair follicles. Caused by HPV and UV radiation exposure. Rapidly enlarging. Dome shaped, centrally plugged keratotic nodule. Sometimes with ulceration. Keratoacanthomas are rapidly growing nodules with a central depression. They mimic cancer, particularly squamous cell carcinoma, except keratoacanthomas have a "very rapid growth", usually over days to weeks. These lesions typically disappear spontaneously and require no treatment.

Early stage of SCC. Associated with HPV infection or over exposure to the sun or to ionizing radiation. Discrete, slowly enlarging thin plaque with irregular border often with scale or crust.

squamous cell carcinoma that has grown into the dermis & adjacent structures where it is able to then metastasize

60% of Actinic Keratoses lesions and 20% Cutaneous Horn develop into this cancer. More serious than basal cell carcinoma; often characterized by scaly red nodules.

Only form to exhibit considerable scaling. Erythematous, pink plaques, smooth with translucence.

Arises from nonkeratinizing basal cells in the deepest layer of the epidermis. Brown, blue, black color. Smooth with translucence. Can be eroded.

Subtype of nodular. Crusted with ulceration, rolled borders similar features to nodular.

Aggressive growth variant. Ivory white appearance, may resemble scar. can progress to nodular or invasive.

Most common form of cancer for young adults. Malignant proliferation of melanocytes at the dermal epidermal junction. Most frequently on trunk of men and legs of women. Begins in nevus or can arise de novo. Black/brown macule.

Malignant proliferation of melanocytes at the dermal epidermal junction. Blue, black, red nodule, ulceration, bleeding.

Most commonly on severely sun damaged skin. Face, nose, and cheek = most common. Slow enlarging, asymmetric brown or black patch.

Occurs on palms and soles. Black streaking in the nails. Always consider for all pigments nail bands in fair skinned individuals: Darkly pigmented and greater than 3mm in width. Higher morbidity.

ABCDEs of Melanoma The border is irregular in shape and one side of a mole or spot does not reflect the other

ABCDE / Border is fuzzy and irregular

ABCDE / Color is not even but multiple shades of tan, brown or black.

ABCDE / diameter is larger than 6mm or the end of a pencil eraser.

ABCDE / evolution: the suspicious mole has changed in color or size over time.

malignant neoplasm normally flat reddish purple to dark blue. most commonly occuring in aids patient

Assymetry, border ,color, diameter, evolution and what is F?